Page last updated: 2024-10-26

doxylamine and Abnormality, Heart

doxylamine has been researched along with Abnormality, Heart in 9 studies

Doxylamine: Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in PARKINSONISM.

Research Excerpts

ExcerptRelevanceReference
"One of twins was born with prune belly syndrome and congenital heart defect following exposure to Bendectin and Tigan."1.27Prune belly syndrome and heart defect in one of monozygotic twins, following exposure to Tigan and Bendectin. ( Greene, C; Shapira, E; Wilson, A, 1985)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Koren, G1
Eskenazi, B1
Bracken, MB1
Mitchell, AA1
Rosenberg, L1
Shapiro, S1
Slone, D1
Check, WA1
Shiono, PH1
Klebanoff, MA1
Zierler, S2
Rothman, KJ1
Hendrickx, AG1
Cukierski, M1
Prahalada, S1
Janos, G1
Rowland, J1
Greene, C1
Wilson, A1
Shapira, E1

Reviews

1 review available for doxylamine and Abnormality, Heart

ArticleYear
Maternal drugs and congenital heart disease.
    Obstetrics and gynecology, 1985, Volume: 65, Issue:2

    Topics: Amphetamines; Analgesics; Anticonvulsants; Demography; Disease Susceptibility; Doxylamine; Drug-Rela

1985

Other Studies

8 other studies available for doxylamine and Abnormality, Heart

ArticleYear
Treating morning sickness in the United States--changes in prescribing are needed.
    American journal of obstetrics and gynecology, 2014, Volume: 211, Issue:6

    Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Approval; Drug Combinations; Female; Heart Defects, Conge

2014
Bendectin (Debendox) as a risk factor for pyloric stenosis.
    American journal of obstetrics and gynecology, 1982, Dec-15, Volume: 144, Issue:8

    Topics: Abnormalities, Drug-Induced; Adult; Dicyclomine; Doxylamine; Drug Combinations; Female; Heart Defect

1982
Birth defects related to bendectin use in pregnancy. I. Oral clefts and cardiac defects.
    JAMA, 1981, Jun-12, Volume: 245, Issue:22

    Topics: Antiemetics; Cleft Lip; Cleft Palate; Dicyclomine; Doxylamine; Drug Combinations; Drug Evaluation; F

1981
CDC study: no evidence for teratogenicity of Bendectin.
    JAMA, 1979, Dec-07, Volume: 242, Issue:23

    Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Heart

1979
Bendectin and human congenital malformations.
    Teratology, 1989, Volume: 40, Issue:2

    Topics: Abnormalities, Drug-Induced; Central Nervous System; Dicyclomine; Digestive System Abnormalities; Do

1989
Congenital heart disease in relation to maternal use of Bendectin and other drugs in early pregnancy.
    The New England journal of medicine, 1985, Aug-08, Volume: 313, Issue:6

    Topics: Acetaminophen; Adult; Anti-Bacterial Agents; Antiemetics; Aspirin; Dicyclomine; Doxylamine; Drug Com

1985
Evaluation of bendectin embryotoxicity in nonhuman primates: I. Ventricular septal defects in prenatal macaques and baboon.
    Teratology, 1985, Volume: 32, Issue:2

    Topics: Animals; Dicyclomine; Dose-Response Relationship, Drug; Doxylamine; Drug Combinations; Female; Fetus

1985
Prune belly syndrome and heart defect in one of monozygotic twins, following exposure to Tigan and Bendectin.
    Acta geneticae medicae et gemellologiae, 1985, Volume: 34, Issue:1-2

    Topics: Benzamides; Dicyclomine; Doxylamine; Drug Combinations; Heart Defects, Congenital; Humans; Prune Bel

1985