doxylamine has been researched along with Abnormalities, Congenital in 8 studies
Doxylamine: Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in PARKINSONISM.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We re-analyzed the 24 primary studies cited in a 1997 meta-analysis that concluded antihistamine use for NVP was safe as they had been studied in more than 200,000 participating women and the pooled odds ratio for congenital malformations was 0." | 6.50 | Re-analysis of safety data supporting doxylamine use for nausea and vomiting of pregnancy. ( Chin, JW; Gregor, S; Persaud, N, 2014) |
| " The NVP Healthline enrolled two control groups of women with NVP treated with a doxylamine-pyridoxine combination for morning sickness." | 5.11 | Is lack of morning sickness teratogenic? A prospective controlled study. ( Boskovic, R; Danieliewska-Nikiel, B; Koren, G; Navioz, Y; Rudic, N, 2004) |
| " We re-analyzed the 24 primary studies cited in a 1997 meta-analysis that concluded antihistamine use for NVP was safe as they had been studied in more than 200,000 participating women and the pooled odds ratio for congenital malformations was 0." | 2.50 | Re-analysis of safety data supporting doxylamine use for nausea and vomiting of pregnancy. ( Chin, JW; Gregor, S; Persaud, N, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chin, JW | 1 |
| Gregor, S | 1 |
| Persaud, N | 1 |
| Slaughter, SR | 1 |
| Hearns-Stokes, R | 1 |
| van der Vlugt, T | 1 |
| Joffe, HV | 1 |
| Boskovic, R | 1 |
| Rudic, N | 1 |
| Danieliewska-Nikiel, B | 1 |
| Navioz, Y | 1 |
| Koren, G | 1 |
| Aselton, P | 1 |
| Jick, H | 1 |
| Milunsky, A | 1 |
| Hunter, JR | 1 |
| Stergachis, A | 1 |
| Danks, DM | 1 |
| Hocking, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prevalence and Burden of Nausea and Vomiting in Pregnant Women in Switzerland: Survey Purity 2022[NCT06055192] | 200 participants (Anticipated) | Observational | 2023-09-30 | Not yet recruiting | |||
| Feasibility and Efficacy of an Internet-delivered Cognitive-behavioral Intervention for Insomnia in a National Cohort of Danish Breast Cancer Survivors[NCT02444026] | 225 participants (Anticipated) | Interventional | 2014-12-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for doxylamine and Abnormalities, Congenital
| Article | Year |
|---|---|
Re-analysis of safety data supporting doxylamine use for nausea and vomiting of pregnancy.
Topics: Antiemetics; Congenital Abnormalities; Doxylamine; Female; Humans; Morning Sickness; Odds Ratio; Pre | 2014 |
1 trial available for doxylamine and Abnormalities, Congenital
| Article | Year |
|---|---|
Is lack of morning sickness teratogenic? A prospective controlled study.
Topics: Adult; Antiemetics; Congenital Abnormalities; Doxylamine; Female; Genetic Counseling; Humans; Matern | 2004 |
6 other studies available for doxylamine and Abnormalities, Congenital
| Article | Year |
|---|---|
FDA approval of doxylamine-pyridoxine therapy for use in pregnancy.
Topics: Antiemetics; Congenital Abnormalities; Dicyclomine; Doxylamine; Drug Approval; Drug Combinations; Fe | 2014 |
Sleep complaints: Whenever possible, avoid the use of sleeping pills.
Topics: Acupuncture Therapy; Adult; Aged; Behavior Therapy; Benzodiazepines; Clinical Trials as Topic; Conge | 2008 |
Congenital malformations.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Dicyclomine; Doxylamine; Drug Combinations; F | 1983 |
First-trimester drug use and congenital disorders.
Topics: Abnormalities, Drug-Induced; Brompheniramine; Congenital Abnormalities; Dicyclomine; Doxylamine; Dru | 1985 |
Blame, compensation and birth defects.
Topics: Abnormalities, Drug-Induced; Australia; Congenital Abnormalities; Dicyclomine; Doxylamine; Drug Comb | 1985 |
Debendox and birth defects.
Topics: Congenital Abnormalities; Dicyclomine; Doxylamine; Drug Combinations; Humans; Infant, Newborn; Pyrid | 1985 |