doxorubicin hydrochloride and Neoplasms

doxorubicin hydrochloride has been researched along with Neoplasms in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's23 (69.70)24.3611
2020's10 (30.30)2.80

Authors

AuthorsStudies
Jahng, Y; Jung, MJ; Karki, R; Kwon, Y; Lee, ES; Na, Y; Nam, JM; Thapa, P; Thapa, U1
Cho, HJ; Jung, MJ; Kim, J; Kwon, Y; Lee, ES; Na, Y; Woo, S1
Agrawal, SK; Rani, R; Roy, P; Saxena, AK; Singh, J; Sondhi, SM1
Kamiie, K; Kidachi, Y; Noshita, T; Ryoyama, K; Umetsu, H; Yamaguchi, H; Yu, T1
Li, J; Wu, X; Zhang, D1
Kamal, A; Kumar, BA; Kumar, MS; Shankaraiah, N; Suresh, P1
Cao, R; Chen, Z; Fan, W; Guo, L; Ma, Q; Shi, B; Song, H; Sun, J1
Gerasimova, Ts; Iliev, I; Kraicheva, I; Kril, A; Tashev, E; Topashka-Ancheva, M; Tosheva, T; Troev, K; Tsacheva, I; Vodenicharova, E1
Hua, WY; Shi, LY; Tang, Y; Wang, K; Wu, JQ; Wu, XM; Wu, YC; Zeng, YF; Zhang, DY; Zhou, B1
Jee, JG; Jun, KY; Kadayat, TM; Karki, R; Kwon, Y; Lee, ES; Lee, JH; Park, C; Thapa, P1
Cheng, K; Gao, P; Li, H; Liao, W; Sun, Q; Wang, X; Xu, G; Zeng, L; Zhang, J1
Chen, Y; Ding, YH; Gao, X; Kuang, BJ; Long, J; Zhang, Q1
Cui, J; Dai, Y; Huang, W; Liu, B; Pan, M; Qian, H; Qiu, Q; Shi, W; Wu, Y1
Arthur, G; Idowu, T; Ogunsina, M; Samadder, P; Schweizer, F1
Cui, J; Dai, Y; Huang, W; Li, Z; Pan, M; Qian, H; Qiu, Q; Shi, W; Zhang, B1
Ding, J; Han, G; Liu, Y; Meng, C; Meng, LH; Qing, L; Shi, J; Wang, Q; Wang, Y; Wang, Z; Yang, Y1
Bist, G; Kwon, Y; Lee, ES; Park, S; Shrestha, A; Song, C; Thapa Magar, TB1
Kumar, K; Kumar, S; Kumar, V; Singh, A1
Bist, G; Kadayat, TM; Kwon, Y; Lee, ES; Lee, HJ; Park, S; Shrestha, A; Thapa Magar, TB1
Chen, J; Feng, D; Gu, X; Jiang, Y; Li, C; Qu, Y; Yin, X1
Kharkar, PS; Shah, CP1
Cai, B; Cui, CB; Li, CW; Wang, N; Xu, LL; Zhu, HJ1
Bi, Y; Li, W; Ma, C; Shuai, W; Sun, H; Xu, F; Xu, J; Xu, S; Yao, H; Zhu, Z1
Dhiman, N; Jaitak, V; Kaur, K1
Ji, A; Li, L; Li, X; Liu, J; Liu, Z; Lou, H; Qian, L; Qiao, Y; Sun, Y; Wang, X; Xu, Y; Zhao, X1
Cheng, K; Fang, Y; Hua, H; Ji, B; Li, D; Li, H; Li, Z; Wu, B; Zheng, C1
Chen, ZS; Li, W; Liu, Y; Shuai, W; Tan, Y; Xu, J; Xu, S; Yang, DH; Yang, L; Yao, H; Zheng, T; Zhu, H; Zhu, Z1
Aaghaz, S; Jain, R; Kamal, A; Sharma, K1
Chen, G; Huang, G; Zhou, S1
Bai, P; Chen, L; Fu, S; Han, K; He, W; Li, J; Li, Y; Liu, J; Liu, Y; Shi, M; Tang, M; Xie, L; Yan, W; Yang, J; Yang, Z; Ye, H; Zhang, C; Zhu, Z1
Cai, Z; Ghaleb, H; Huang, W; Jiang, Y; Liu, Y; Qian, H; Qiu, Q; Shi, W; Yin, Z; Zhang, P; Zhou, J; Zou, F1
Li, X; Lin, H; OuYang, F; Pang, Y; Yan, J; Zhang, W; Zhou, J1
Valipour, M1

Reviews

6 review(s) available for doxorubicin hydrochloride and Neoplasms

ArticleYear
Recent insights into synthetic β-carbolines with anti-cancer activities.
    European journal of medicinal chemistry, 2017, Dec-15, Volume: 142

    Topics: Animals; Antineoplastic Agents; Carbolines; Chemistry Techniques, Synthetic; Drug Discovery; Humans; Neoplasms; Structure-Activity Relationship

2017
Tetrazoles as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies.
    Bioorganic & medicinal chemistry, 2020, 08-01, Volume: 28, Issue:15

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Molecular Structure; Neoplasms; Structure-Activity Relationship; Tetrazoles

2020
Renieramycin-type alkaloids from marine-derived organisms: Synthetic chemistry, biological activity and structural modification.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Alkaloids; Anti-Infective Agents; Antibiotics, Antineoplastic; Antiprotozoal Agents; Biological Products; Molecular Structure; Neoplasms; Tetrahydroisoquinolines

2021
β-Carbolines as potential anticancer agents.
    European journal of medicinal chemistry, 2021, Apr-15, Volume: 216

    Topics: Antineoplastic Agents; Carbolines; Cyclin-Dependent Kinases; DNA Topoisomerases; Humans; Intercalating Agents; Neoplasms; Plants; Proto-Oncogene Proteins B-raf; Tubulin

2021
Synthesis and anti-tumor activity of marine alkaloids.
    Bioorganic & medicinal chemistry letters, 2021, 06-01, Volume: 41

    Topics: Alkaloids; Antineoplastic Agents; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms

2021
Recent advances of antitumor shikonin/alkannin derivatives: A comprehensive overview focusing on structural classification, synthetic approaches, and mechanisms of action.
    European journal of medicinal chemistry, 2022, May-05, Volume: 235

    Topics: Antineoplastic Agents; Apoptosis; Humans; Naphthoquinones; Neoplasms

2022

Other Studies

27 other study(ies) available for doxorubicin hydrochloride and Neoplasms

ArticleYear
2-Thienyl-4-furyl-6-aryl pyridine derivatives: synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Neoplasms; Pyrimidines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2010
New benzoxanthone derivatives as topoisomerase inhibitors and DNA cross-linkers.
    Bioorganic & medicinal chemistry, 2010, Volume: 18, Issue:3

    Topics: Antineoplastic Agents; Benzene Derivatives; Cell Line, Tumor; Cell Proliferation; DNA; DNA Topoisomerases; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topoisomerase Inhibitors; Xanthones

2010
Solvent free synthesis, anti-inflammatory and anticancer activity evaluation of tricyclic and tetracyclic benzimidazole derivatives.
    Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Benzimidazoles; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Microwaves; Neoplasms; Ovarian Neoplasms

2010
Novel effects of glycyrrhetinic acid on the central nervous system tumorigenic progenitor cells: induction of actin disruption and tumor cell-selective toxicity.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:7

    Topics: Actins; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Central Nervous System; Genes, myc; Genes, ras; Glycyrrhetinic Acid; Humans; Mice; Neoplasms; Stem Cells; Transfection

2010
Synthesis and biological evaluation of novel exo-methylene cyclopentanone tetracyclic diterpenoids as antitumor agents.
    Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cyclopentanes; Diterpenes; Diterpenes, Kaurane; Drug Screening Assays, Antitumor; Humans; Neoplasms

2011
An efficient one-pot synthesis of benzothiazolo-4β-anilino-podophyllotoxin congeners: DNA topoisomerase-II inhibition and anticancer activity.
    Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1

    Topics: Antineoplastic Agents; Benzothiazoles; Cell Line, Tumor; Chlorides; DNA Topoisomerases, Type II; Halogenation; Humans; Neoplasms; Podophyllotoxin; Topoisomerase II Inhibitors; Zirconium

2011
Synthesis and biological evaluation of 1,9-disubstituted β-carbolines as potent DNA intercalating and cytotoxic agents.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:10

    Topics: Antineoplastic Agents; Carbolines; Cell Line, Tumor; Cytotoxins; DNA; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Intercalating Agents; Neoplasms

2011
Synthesis, antiproliferative activity and genotoxicity of novel anthracene-containing aminophosphonates and a new anthracene-derived Schiff base.
    Bioorganic & medicinal chemistry, 2012, Jan-01, Volume: 20, Issue:1

    Topics: Animals; Anthracenes; Antineoplastic Agents; Cell Line; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Mice; Neoplasms; Organophosphonates; Schiff Bases

2012
Synthesis and evaluation of cytotoxic effects of novel α-methylenelactone tetracyclic diterpenoids.
    Bioorganic & medicinal chemistry letters, 2012, Mar-01, Volume: 22, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Diterpenes; Humans; Lactones; Neoplasms; Structure-Activity Relationship

2012
Synthesis, antitumor activity, and structure-activity relationship study of trihydroxylated 2,4,6-triphenyl pyridines as potent and selective topoisomerase II inhibitors.
    European journal of medicinal chemistry, 2014, Sep-12, Volume: 84

    Topics: Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Molecular Docking Simulation; Molecular Structure; Neoplasms; Phenols; Pyridines; Structure-Activity Relationship; Topoisomerase II Inhibitors

2014
Synthesis and biological evaluation of a novel class of coumarin derivatives.
    Bioorganic & medicinal chemistry letters, 2014, Nov-15, Volume: 24, Issue:22

    Topics: Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; Cell Survival; Circular Dichroism; Coumarins; DNA; Doxorubicin; Humans; Mice; Neoplasms; Transplantation, Heterologous

2014
Dispirocyclopropyldehydrocostus lactone selectively inhibits acute myelogenous leukemia cells.
    Bioorganic & medicinal chemistry letters, 2016, Feb-15, Volume: 26, Issue:4

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Humans; Lactones; Leukemia, Myeloid, Acute; Mice; Mice, SCID; Neoplasms; Poly(ADP-ribose) Polymerases; Prodrugs; Sesquiterpenes; Transplantation, Heterologous; Up-Regulation

2016
Design, synthesis and biological evaluation of LBM-A5 derivatives as potent P-glycoprotein-mediated multidrug resistance inhibitors.
    Bioorganic & medicinal chemistry, 2016, 05-15, Volume: 24, Issue:10

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzamides; Click Chemistry; Doxorubicin; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; K562 Cells; Neoplasms; Structure-Activity Relationship; Tetrahydroisoquinolines

2016
Replacing d-Glucosamine with Its l-Enantiomer in Glycosylated Antitumor Ether Lipids (GAELs) Retains Cytotoxic Effects against Epithelial Cancer Cells and Cancer Stem Cells.
    Journal of medicinal chemistry, 2017, 03-09, Volume: 60, Issue:5

    Topics: Epithelium; Glucosamine; Glycosylation; Humans; Neoplasms; Neoplastic Stem Cells; Stereoisomerism

2017
Exploration of 2-((Pyridin-4-ylmethyl)amino)nicotinamide Derivatives as Potent Reversal Agents against P-Glycoprotein-Mediated Multidrug Resistance.
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Doxorubicin; Drug Discovery; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; K562 Cells; Neoplasms; Niacinamide

2017
6-OH-Phenanthroquinolizidine Alkaloid and Its Derivatives Exert Potent Anticancer Activity by Delaying S Phase Progression.
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Neoplasms; Phenanthrolines; Quinolizines; S Phase

2017
Dihydroxylated 2,6-diphenyl-4-chlorophenylpyridines: Topoisomerase I and IIα dual inhibitors with DNA non-intercalative catalytic activity.
    European journal of medicinal chemistry, 2017, Jun-16, Volume: 133

    Topics: Antineoplastic Agents; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; Halogenation; Humans; Neoplasms; Pyridines; Topoisomerase II Inhibitors

2017
2-Chlorophenyl-substituted benzofuro[3,2-b]pyridines with enhanced topoisomerase inhibitory activity: The role of the chlorine substituent.
    Bioorganic & medicinal chemistry letters, 2017, 08-01, Volume: 27, Issue:15

    Topics: Antineoplastic Agents; Benzofurans; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Halogenation; Humans; Neoplasms; Pyridines; Topoisomerase Inhibitors

2017
Synthesis and biological evaluation of bifendate derivatives bearing 6,7-dihydro-dibenzo[c,e]azepine scaffold as potential P-glycoprotein and tumor metastasis inhibitors.
    European journal of medicinal chemistry, 2018, Feb-10, Volume: 145

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azepines; Biphenyl Compounds; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; K562 Cells; Molecular Structure; Neoplasms; Structure-Activity Relationship

2018
Discovery of novel human inosine 5'-monophosphate dehydrogenase 2 (hIMPDH2) inhibitors as potential anticancer agents.
    European journal of medicinal chemistry, 2018, Oct-05, Volume: 158

    Topics: Animals; Antineoplastic Agents; Benzene Derivatives; Cell Line, Tumor; Cell Survival; Drug Discovery; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Mice; Molecular Docking Simulation; Neoplasms; NIH 3T3 Cells; Small Molecule Libraries; Structure-Activity Relationship

2018
Four new antitumor metabolites isolated from a mutant 3-f-31 strain derived from Penicillium purpurogenum G59.
    European journal of medicinal chemistry, 2018, Oct-05, Volume: 158

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Products; Cell Line, Tumor; HCT116 Cells; Humans; Mice; Models, Molecular; Mutation; Neoplasms; Penicillium

2018
Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site.
    European journal of medicinal chemistry, 2019, Feb-01, Volume: 163

    Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Colchicine; Drug Design; Drug Screening Assays, Antitumor; Heterografts; Humans; Indoles; K562 Cells; Neoplasms; Quinolines; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2019
Discovery of lysosome-targeted covalent anticancer agents based on isosteviol skeleton.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: A549 Cells; Antineoplastic Agents; Cell Death; Diterpenes, Kaurane; Drug Design; Humans; Lysosomes; Neoplasms

2021
Discovery of novel N-benzylbenzamide derivatives as tubulin polymerization inhibitors with potent antitumor activities.
    European journal of medicinal chemistry, 2021, Apr-15, Volume: 216

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Binding Sites; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Design; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Inbred ICR; Molecular Docking Simulation; Neoplasms; Neovascularization, Physiologic; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2021
Structure-Based Design and Synthesis of N-Substituted 3-Amino-β-Carboline Derivatives as Potent αβ-Tubulin Degradation Agents.
    Journal of medicinal chemistry, 2022, 02-10, Volume: 65, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Binding Sites; Carbolines; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; G2 Phase Cell Cycle Checkpoints; Humans; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms; Protein Binding; Rats; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Xenograft Model Antitumor Assays

2022
Exploration of novel phthalazinone derivatives as potential efflux transporter inhibitors for reversing multidrug resistance and improving the oral absorption of paclitaxel.
    European journal of medicinal chemistry, 2022, Apr-05, Volume: 233

    Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasm Proteins; Neoplasms; Paclitaxel

2022
Discovery of a Novel Stilbene Derivative as a Microtubule Targeting Agent Capable of Inducing Cell Ferroptosis.
    Journal of medicinal chemistry, 2022, 03-24, Volume: 65, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Ferroptosis; Humans; Microtubules; Neoplasms; Stilbenes

2022