Page last updated: 2024-08-22

doxifluridine and Colonic Neoplasms

doxifluridine has been researched along with Colonic Neoplasms in 91 studies

Research

Studies (91)

Timeframe	Studies, this research(%)	All Research%
pre-1990	38 (41.76)	18.7374
1990's	31 (34.07)	18.2507
2000's	19 (20.88)	29.6817
2010's	3 (3.30)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Abe, H; Edamatsu, T; Fujieda, A; Fujioka, M; Mekata, E; Murata, S; Naka, S; Shimizu, T; Shiomi, H; Sonoda, H; Tani, T; Umeda, T; Wada, T; Yamamoto, H	1
Gao, Q; Liu, J; Liu, Y; Wang, QW; Ye, DJ; Zhang, JM	1
Wang, QW; Xia, Q; Zhang, JM	1
Kabashima, A; Kajiyama, K; Kuma, S; Sakaguchi, Y	1
Fujiwara, S; Kikuchi, R; Noguchi, T; Suehiro, S; Uchida, Y	1
Kitami, C; Maruyama, S; Nihei, K; Tamiya, Y	1
Creer, S; Ishii, H; Kuroki, T; Mimori, K; Mori, M; Shiraishi, T; Taylor, S; Ueo, H	1
Hayakawa, K; Miyake, K; Morimoto, T; Mukaihara, S; Nishino, M	1
Fujio, N; Fukuda, Y; Ihara, T; Koyama, I; Osugi, H; Takatori, H; Tsukazaki, T; Tsukazaki, Y	1
Ebisui, C; Fujimoto, T; Fujiwara, S; Fukuchi, S; Hasuike, Y; Hayashi, N; Kida, H; Sakita, I; Tsujie, M; Yoshida, T	1
Hiro, J; Inoue, Y; Kusunoki, M; Miki, C; Nakatani, K; Nobori, T; Ojima, E; Toiyama, Y; Watanabe, H	1
Cricca, S; de Bruin, M; Laan, AC; Peters, GJ; Temmink, OH; Turksma, AW	1
Peters, GJ; Prins, HJ; Temmink, OH; van Gelderop, E	1
Ishizu, K; Makuuchi, H; Sadahiro, S; Sunose, N; Tsuruo, T; Yamazaki, K; Yamori, T	1
Aubert, C; Cano, JP; Gouveia, J; Mathé, G; Ribaud, P; Sommadossi, JP	1
Armstrong, RD; Cadman, E	1
Armstrong, RD; Cadman, E; Gesmonde, J; Wu, T	1
Abele, R; Alberto, P; Cavalli, F; Hartmann, D; Hofmann, V; Holdener, EE; Kaplan, S; Ryssel, HJ; Siegenthaler, P	1
Fujita, F; Fujita, M; Taguchi, T	1
Hara, Y; Kono, A; Tanaka, M	1
Cooper, AJ; Goeting, N; Morgan, GR; Taylor, I; Trotter, GA	1
Fujioka, A; Nakano, K; Okabe, H; Saito, H; Takeda, S; Toko, T; Unemi, N	1
Cao, S; Durrani, FA; Mayhew, EG; Peters, GJ; Rustum, YM; Van Laar, JA	1
Fujimoto, T; Iihara, K; Kitada, M; Murotani, M; Okumura, Y; Shibata, T; Takada, T; Takami, M; Tsukahara, Y; Watanabe, T	1
Eliason, JF; Givel, JC; Laurent, PL; Odartchenko, N; Tevaearai, HT	1
De Bruijn, EA; Eggermont, A; Gheuens, E; Van Bockstaele, D; van de Vrie, W; van der Heyden, S; Van Oosterom, A	1
Jin, H; Kano, M; Kinugasa, A; Nishigami, T; Sawada, K; Shimoyama, T; Shintani, S; Wada, M; Yamamura, M; Yamashita, M	1
Eda, H; Fujimoto, K; Hino, A; Ishitsuka, H; Tanaka, Y; Ura, M; Wada, K; Watanabe, S	1
Fukuda, I; Irie, K; Iwanaga, T; Kikkawa, N; Okumura, S; Sakai, K; Shimoyama, T; Taguchi, T; Terasawa, T; Yasutake, K	1
Eda, H; Fujimoto, K; Ishikawa, T; Ishitsuka, H; Ohiwa, T; Tanaka, Y; Tatsuno, K; Watanabe, S	1
Hirano, M; Kato, A; Kikkawa, H; Kitagawa, K; Masuda, S; Mori, H; Murakami, N; Oosawa, T; Saito, H; Watanabe, S	1
Taguchi, T	1
Andou, T; Hori, K; Kimura, S; Koumoto, T; Takagaki, M; Tsuji, K	1
Arano, Y; Hirano, M; Ishikawa, N; Kikuchi, T; Kitsukawa, H; Kurokawa, M; Murakami, N; Nagao, S; Saito, H	1
Fujiwara, K; Gotoh, K; Houkan, T; Midoro, K; Ootsu, K; Yukishige, K	1
Fujimaki, M; Katuyama, S; Kuroki, Y; Okamoto, M; Sakamoto, T; Tazawa, K; Yamashita, I	1
Asano, K; Fujita, H; Izumi, R; Kanno, M; Kojima, Y; Konishi, K; Matsuki, N; Miyata, R; Miyazaki, I; Mura, T; Nishimura, G; Ooto, T; Sasaki, T; Sawa, T; Syouji, M; Takada, M; Takeyama, S; Takigawa, Y; Takita, Y; Ueda, H; Ueno, K; Yamazaki, H	1
Henmi, K; Ishida, Y; Iwai, N; Kaneko, I; Matsumoto, S; Nabeyama, A; Nakamoto, M; Ohtoshi, M; Ono, S; Shibagaki, F; Soda, M; Takao, K; Yamasaki, T; Yamasaki, Y	1
Cano, JP; Cuq, P; Evrard, A; Pèlegrin, A; Robert, B; Vian, L	1
Ishikawa, S; Miyazaki, M; Morimoto, Y; Nagai, I; Sumimura, J	1
Fujiwara, Y; Kanyama, H; Miyoshi, Y; Monden, M; Ohue, M; Sakita, I; Sekimoto, M; Tamaki, Y; Tomita, N; Yamano, T	1
Field, WN; Hussey, HJ; Inagaki, N; Ishitsuka, H; Tanaka, Y; Tisdale, MJ; Todorov, PT	1
Ashino, Y; Kanno, A; Kanzaki, N; Kashimura, S; Kawahara, Y; Miyazawa, M; Muto, A; Sato, M	1
Aoki, S; Hamamatsu, C; Hirata, K; Hirayama, T; Kawasaki, H; Matsunaga, T; Nakagawa, N; Nakayama, I; Oono, K; Sasaki, K; Shibata, K; Takaoka, A; Takasaka, H; Yabana, T; Yamamoto, Y	1
Chazal, M; Dubreuil, A; Etienne, MC; Fischel, JL; Marchetti, S; Milano, G	1
Araki, Y; Hayashi, A; Ishibashi, N; Kishimoto, Y; Konishi, J; Matono, K; Mituoka, M; Miyagi, Y; Nakagawa, M; Nozoe, Y; Ogata, Y; Sasatomi, T; Shirouzu, K	1
Aoyagi, K; Basaki, Y; Chikahisa, L; Hashimoto, A; Miyadera, K; Okabe, S; Wierzba, K; Yamada, Y; Yonekura, K	1
Iwahashi, M; Nagata, T; Nakamori, M; Yamaue, H	1
Hotokezaka, M; Ishimitsu, T; Matsumoto, S; Nakamura, K; Takeda, S	1
Cloos, J; Noordhuis, P; Peters, GJ; Pinedo, HM; Smid, K; van der Wilt, CL	1
Eda, H; Fujimoto, K; Ishikawa, T; Ishitsuka, H; Tanaka, T; Tanaka, Y	1
Fukuda, S; Iwasaki, Y; Kawai, Y; Miyamoto, H; Nozue, M; Todoroki, T; Ueda, H	1
Maeda, H; Miyamoto, T; Mochinaga, N; Tsunoda, T	1
Fujimaki, M; Kurokawa, M; Kuroki, Y; Ochiai, H; Okamoto, M; Tazawa, K; Yamashita, I	1
Kawahara, T; Kikkawa, N; Kobayakawa, K; Tsuchiya, Y; Tsumura, I	1
Eda, H; Ishitsuka, H; Tanaka, Y	1
De Clercq, E; Iigo, M; Miwa, M	1
Arima, S; Fukamura, T; Haruta, J; Hashimoto, M; Jyozaki, H; Okamoto, K; Shimura, H; Umeno, T	1
Inaba, M; Mitsuhashi, J; Ozawa, S	1
Adachi, I; Douden, K; Hayashi, H; Hikishima, H; Iwa, T; Munemoto, Y; Okada, Y; Omura, K; Watanabe, Y	1
Braakhuis, BJ; de Bruijn, EA; Laurensse, EJ; Peters, GJ; Pinedo, HM; van Walsum, M	1
Araki, E; Hoshi, A; Iigo, M; Nakajima, Y	1
Baba, T; Furukohri, N; Itoh, T; Munakata, A; Ogasawara, H; Saitoh, S; Sakata, Y; Tamura, Y; Tsushima, K; Yoshida, Y	1
Imamura, Y; Matsusita, K; Okutani, T; Ono, S; Oya, M; Tokisue, M; Yasutake, K; Yoshimura, Y	1
Ishikawa, T; Ishitsuka, H; Ohkawa, T; Tanaka, Y	1
Decoster, G; Heim, ME; Queisser, W; Schuster, D	1
Braakhuis, BJ; Laurensse, EJ; Peters, GJ; Pinedo, HM	1
Furue, H; Kanamaru, R; Kimura, K; Komita, T; Murakami, M; Nakao, I; Ohta, K; Saito, T; Wakui, A; Yokoyama, M	1
Abe, O; Kimura, K; Kimura, T; Kurihara, M; Nakao, I; Niitani, H; Ohta, K; Saito, T; Urushizaki, I; Yoshida, Y	1
Hayashi, K; Kitamura, M; Kosaki, G; Takahashi, I; Tominaga, T	1
Irie, K; Kawahara, T; Okajima, K; Sakai, K; Satomi, T; Taguchi, T; Terasawa, T; Tomita, K; Yamaguchi, A; Yamamoto, M	1
Okumura, T	1
Fosså, SD; Heier, MS	2
Armand, JP; Bastit, P; Cappelaere, P; Fargeot, P; Fumoleau, P; Hurteloup, P; Keiling, R; Kerbrat, P; Metz, R; Schraub, S	1
Faure, F; Hollande, E; Malet-Martino, MC; Martino, R; Palevody, C; Vialaneix, JP	1
Hachisuka, K; Hiraiwa, K; Hoshino, A; Kamiya, O; Kinoshita, T; Murakami, M; Ota, K; Yamada, M; Yamaguchi, A; Yasue, M	1
Lankelma, J; Laurensse, EJ; Leyva, A; Peters, GJ; Pinedo, HM; van Dijk, J; van Groeningen, C	1
Fujita, F; Fujita, M; Shimozuma, K; Taguchi, T	1
Aas, M; Flokkmann, A; Fosså, SD; Heier, M; Heintz, R; Linder-Ciccolunghi, S; Moe, B	1
Au, JL; Canobbio, L; Rustum, YM; Trave, F	1
Fujita, F; Fujita, M; Inaba, H; Sakamoto, Y; Shimozuma, K; Taguchi, T	1
Fujita, F; Fujita, M; Inaba, H; Sakamoto, Y; Shimozuma, K; Taguchi, T; Yamauchi, T	1
Berger, MR; Garzon, FT; Keppler, BK; Schmähl, D	1
Armand, JP; Bernadou, J; Malet-Martino, MC; Martino, R; Roché, H	1
Eda, H; Fukuda, H; Ishikawa, T; Ishitsuka, H; Matsuura, N; Miwa, M; Ninomiya, Y; Tanaka, Y	1
Eda, H; Fujimoto, K; Fukuda, H; Ishitsuka, H; Miwa, M	1
Alberto, P; Cavalli, F; Germano, G; Joss, R; Kaplan, S; Martz, G; Mermillod, B; Spati, B; Weber, W	1
Alley, PA; Choong, YS; Lee, SP	1
Almersjö, O; Berne, M; Gustavsson, B; Spears, P; Sundström, E	1
Gocho, Y; Ishitani, K; Kogo, Y; Kouda, K; Koyama, R; Matsuda, M; Nagai, T; Niitsu, Y; Saijo, N; Urushizaki, I	1

Reviews

1 review(s) available for doxifluridine and Colonic Neoplasms

Article

Year

[Survival and changes of clinical laboratory data in phase II study with 5'-DFUR].

Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:8

Topics: Administration, Oral; Animals; Antineoplastic Agents; Blood Cell Count; Breast Neoplasms; Cachexia; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Humans; Male; Neoplasms, Experimental; Rectal Neoplasms; Remission Induction; Stomach Neoplasms; Survival Rate

1996

Trials

7 trial(s) available for doxifluridine and Colonic Neoplasms

Article	Year
[Survival and changes of clinical laboratory data in phase II study with 5'-DFUR]. Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:8 Topics: Administration, Oral; Animals; Antineoplastic Agents; Blood Cell Count; Breast Neoplasms; Cachexia; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Humans; Male; Neoplasms, Experimental; Rectal Neoplasms; Remission Induction; Stomach Neoplasms; Survival Rate	1996
[Significance of 5'-deoxy-5-fluorouridine (5'-DFUR) administration before surgery for advanced gastric and colonic cancers--activity of pyrimidine nucleoside phosphorylase (PyNPase) and serum immunosuppressive acidic protein (IAP)]. Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:14 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Humans; Immunosuppressive Agents; Male; Middle Aged; Neoplasm Proteins; Pentosyltransferases; Preoperative Care; Pyrimidine Phosphorylases; Stomach Neoplasms	1996
[Comparative study of 5'-DFUR administration in patients with elderly cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:11 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Colonic Neoplasms; Female; Floxuridine; Humans; Male; Pilot Projects; Stomach Neoplasms	1998
[Clinical trial of 5'-DFUR against various malignant tumors]. Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:12 Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasms; Stomach Neoplasms	1985
Wernicke-Korsakoff-like syndrome in patients with colorectal carcinoma treated with high-dose doxifluridine (5'-dFUrd). Acta neurologica Scandinavica, 1986, Volume: 73, Issue:5 Topics: Adult; Aged; Brain Diseases; Carcinoid Tumor; Carcinoma; Cerebellar Diseases; Colonic Neoplasms; Electroencephalography; Electromyography; Female; Floxuridine; Humans; Male; Middle Aged; Nervous System Diseases; Neural Conduction; Neurologic Examination; Rectal Neoplasms; Time Factors; Wernicke Encephalopathy	1986
Phase I/II tolerability/pharmacokinetic study with one-hour intravenous infusion of doxifluiridine (5'-dFUrd) 3 g/m2 VS 5 g/m2 QD x 5 per month. Cancer chemotherapy and pharmacology, 1986, Volume: 18, Issue:3 Topics: Adenocarcinoma; Antineoplastic Agents; Cecal Neoplasms; Colonic Neoplasms; Drug Evaluation; Drug Tolerance; Female; Floxuridine; Humans; Infusions, Intravenous; Male; Middle Aged; Random Allocation; Rectal Neoplasms; Sigmoid Neoplasms; Time Factors	1986
A randomized comparison of doxifluridine and fluorouracil in colorectal carcinoma. European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:3 Topics: Adenocarcinoma; Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Humans; Male; Middle Aged; Random Allocation; Rectal Neoplasms	1988

Other Studies

84 other study(ies) available for doxifluridine and Colonic Neoplasms

Article	Year
Protein-bound polysaccharide-K augments the anticancer effect of fluoropyrimidine derivatives possibly by lowering dihydropyrimidine dehydrogenase expression in gastrointestinal cancers. Oncology reports, 2013, Volume: 30, Issue:6 Topics: Antineoplastic Agents; Cell Proliferation; Colonic Neoplasms; Dihydrouracil Dehydrogenase (NADP); Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Leukocytes, Mononuclear; Polysaccharides; Protein Binding; Thymidylate Synthase	2013
[Enhanced anticancer effects of 5'-DFUR on colorectal cancer cell lines SW480 and LOVO by transfection with thymidine phosphorylase cDNA]. Zhonghua wai ke za zhi [Chinese journal of surgery], 2013, Volume: 51, Issue:7 Topics: Cell Line, Tumor; Colonic Neoplasms; Floxuridine; Fluorouracil; Humans; Thymidine Phosphorylase; Transcription, Genetic; Transfection	2013
[Influence of interferon-α2a on thymidine phosphorylase expression and anticancer activity of 5'-deoxy-fluorouridine in human colon carcinoma cell lines LOVO and SW480]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2012, Volume: 15, Issue:7 Topics: Cell Line, Tumor; Colonic Neoplasms; Floxuridine; Humans; Interferon alpha-2; Interferon-alpha; Recombinant Proteins; Thymidine Phosphorylase	2012
[A case of liver metastasis of colon cancer demonstrating complete remission with combination chemotherapy of 5'-DFUR and MMC]. Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:6 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Floxuridine; Hepatectomy; Humans; Liver Neoplasms; Male; Mitomycin; Remission Induction	2003
[A case of multiple lung metastases of colon cancer with long-term survival following 5'-DFUR and cimetidine therapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:8 Topics: Adenocarcinoma; Adjuvants, Immunologic; Aged; Antimetabolites, Antineoplastic; Cimetidine; Colonic Neoplasms; Drug Therapy, Combination; Female; Floxuridine; Histamine H2 Antagonists; Humans; Lung Neoplasms	2003
[A case of multiple liver metastases of colon cancer with PyNPase-positive successfully treated with 5'-DFUR]. Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:10 Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Floxuridine; Humans; Liver Neoplasms; Male; Pentosyltransferases; Pyrimidine Phosphorylases; Remission Induction	2003
Prediction of 5'-deoxy-5-fluorouridine sensitivity in colorectal cancer cases by thymidine phosphorylase activity and preliminary identification of susceptibility related genes. Oncology reports, 2004, Volume: 12, Issue:1 Topics: Aged; Antimetabolites, Antineoplastic; Cell Division; Cell Line, Tumor; Colonic Neoplasms; Colorectal Neoplasms; Female; Floxuridine; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Male; Middle Aged; RNA, Messenger; Thymidine Phosphorylase	2004
Effects of oral 5-fluorouracil drugs on hepatic fat content in patients with colon cancer. Academic radiology, 2005, Volume: 12, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Chi-Square Distribution; Colonic Neoplasms; Fatty Liver; Female; Floxuridine; Fluorouracil; Humans; Male; Middle Aged; Retrospective Studies; Tegafur; Tomography, X-Ray Computed; Uracil	2005
[A case of advanced gastric cancer with direct invasion of the transverse colon responding to paclitaxel/5'-DFUR combined therapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:12 Topics: Adenocarcinoma, Scirrhous; Antineoplastic Combined Chemotherapy Protocols; Colon, Transverse; Colonic Neoplasms; Drug Administration Schedule; Floxuridine; Humans; Ileus; Male; Middle Aged; Neoplasm Invasiveness; Paclitaxel; Peritoneal Neoplasms; Quality of Life; Stomach Neoplasms	2005
[A case of metastatic colon cancer treated with oxaliplatin combination chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:11 Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Floxuridine; Humans; Irinotecan; Liver Neoplasms; Male; Organoplatinum Compounds; Oxaliplatin; Quality of Life	2005
Irinotecan cytotoxicity does not necessarily depend on the UGT1A1 polymorphism but on fluoropyrimidine: a molecular case report. Oncology reports, 2006, Volume: 16, Issue:5 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Glucuronosyltransferase; Humans; Irinotecan; Polymorphism, Genetic	2006
Activity and substrate specificity of pyrimidine phosphorylases and their role in fluoropyrimidine sensitivity in colon cancer cell lines. The international journal of biochemistry & cell biology, 2007, Volume: 39, Issue:3 Topics: Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhibitors; Floxuridine; Humans; Kinetics; Pyrimidines; Substrate Specificity; Thymidine Phosphorylase; Uridine; Uridine Phosphorylase	2007
The Hollow Fibre Assay as a model for in vivo pharmacodynamics of fluoropyrimidines in colon cancer cells. British journal of cancer, 2007, Jan-15, Volume: 96, Issue:1 Topics: Administration, Oral; Animals; Apoptosis; Capecitabine; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Deoxycytidine; Drug Combinations; Drug Synergism; Enzyme Inhibitors; Flow Cytometry; Floxuridine; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Pyrrolidines; Sensitivity and Specificity; Thymidine Phosphorylase; Thymine; Treatment Outcome; Trifluridine; Tumor Cells, Cultured; Uracil; Xenograft Model Antitumor Assays	2007
Development and characterization of a model of liver metastasis using human colon cancer HCT-116 cells. Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:9 Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Adhesion; Cell Line, Tumor; Collagen Type II; Colonic Neoplasms; Female; Fibronectins; Floxuridine; Fluorouracil; Humans; Irinotecan; Laminin; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mice, Nude; Models, Biological; Neoplasm Metastasis; Paclitaxel	2007
Kinetics and metabolism of a new fluoropyrimidine, 5'-deoxy-5-fluorouridine, in humans. Cancer research, 1983, Volume: 43, Issue:2 Topics: Colonic Neoplasms; Drug Evaluation; Floxuridine; Humans; Isomerism; Kinetics; Neoplasm Metastasis; Pancreatic Neoplasms	1983
5'-Deoxy-5-fluorouridine selective toxicity for human tumor cells compared to human bone marrow. Cancer research, 1983, Volume: 43, Issue:6 Topics: Antineoplastic Agents; Bone Marrow; Breast Neoplasms; Cell Survival; Colonic Neoplasms; Floxuridine; Fluorouracil; Humans; Leukemia, Myeloid, Acute; Neoplasms; Osteosarcoma	1983
Cytotoxic activity of 5'-deoxy-5-fluorouridine in cultured human tumors. Cancer treatment reports, 1983, Volume: 67, Issue:6 Topics: Breast Neoplasms; Cell Line; Cell Survival; Colonic Neoplasms; Drug Evaluation, Preclinical; Female; Floxuridine; Humans; Lethal Dose 50; Leukemia, Myeloid, Acute; Neoplasms; Osteosarcoma; Pancreatic Neoplasms	1983
Phase II study of doxifluridine in advanced colorectal adenocarcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:12 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Chemical Phenomena; Chemistry; Colonic Neoplasms; Drug Eruptions; Drug Evaluation; Female; Floxuridine; Heart; Humans; Leukopenia; Male; Middle Aged; Nausea; Rectal Neoplasms; Thrombocytopenia; Vomiting	1983
[Effects of 5'-deoxy-5-fluorouridine on human gastrointestinal and breast cancers xenografted to nude mice]. Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:8 Topics: Adenocarcinoma; Administration, Oral; Animals; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Floxuridine; Humans; Male; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Rectal Neoplasms; Stomach Neoplasms; Tegafur	1984
[Measurement of 5'-deoxy-5-fluorouridine (5'-DFUR) by high-performance liquid chromatography and studies on pharmacokinetics of 5'-DFUR and 5-fluorouracil by oral and intravenous administration]. Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:10 Topics: Administration, Oral; Aged; Chromatography, High Pressure Liquid; Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Humans; Injections, Intravenous; Kinetics; Male; Middle Aged; Stomach Neoplasms	1984
Prognostic factors and in vitro cytotoxic sensitivity in colorectal cancer. The British journal of surgery, 1984, Volume: 71, Issue:12 Topics: Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Colonic Neoplasms; Floxuridine; Fluorouracil; Humans; Neoplasm Staging; Prognosis; Rectal Neoplasms; Thymidine; Tumor Stem Cell Assay	1984
[Augmentation of chemotherapeutic efficaciousness of UFT by oral l-leucovorin--growth-inhibitory activity of combination against human tumor xenograft]. Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:13 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Floxuridine; Humans; Leucovorin; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Tegafur; Transplantation, Heterologous; Uracil	1995
Modulation of the antitumour activity of cisplatin alone and in combination with 5-fluoro-2'-deoxyuridine by N-phosphonacetyl-L-aspartate in murine colon carcinoma no. 26. European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:6 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cisplatin; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Interactions; Female; Floxuridine; Mice; Mice, Inbred BALB C; Phosphonoacetic Acid; Tumor Cells, Cultured	1995
[A case of pulmonary metastasis from colon cancer successfully treated with high-dose 5'-DFUR]. Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:1 Topics: Adenocarcinoma; Antineoplastic Agents; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Floxuridine; Humans; Lung Neoplasms; Male; Middle Aged; Pneumonectomy; Remission Induction	1995
Interferon alpha and 5'-deoxy-5-fluorouridine in colon cancer: effects as single agents and in combination on growth of xenograft tumours. European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:12 Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Floxuridine; Fluorouracil; Humans; Interferon Type I; Male; Mice; Mice, Nude; Neoplasm Transplantation; Pentosyltransferases; Prodrugs; Pyrimidine Phosphorylases; Recombinant Proteins; Transplantation, Heterologous	1994
5'-Deoxy-5-fluorouridine increases daunorubicin uptake in multidrug-resistant cells and its activity is related with P-gp 170 expression. Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma; Carrier Proteins; Colonic Neoplasms; Daunorubicin; Drug Resistance; Flow Cytometry; Floxuridine; Membrane Glycoproteins; Prodrugs; Rats; Tumor Cells, Cultured	1994
Simultaneous occurrence of adenomas in stomach, duodenal bulb, and colon: disappearance of gastric and duodenal adenomas during oral administration of 5'-deoxy-5-fluorouridine. The American journal of gastroenterology, 1994, Volume: 89, Issue:11 Topics: Adenoma; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Colonic Neoplasms; Duodenal Neoplasms; Floxuridine; Humans; Isomerism; Liver Neoplasms; Male; Neoplasms, Multiple Primary; Stomach Neoplasms	1994
Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5'-deoxy-5-fluorouridine. Cancer chemotherapy and pharmacology, 1993, Volume: 32, Issue:5 Topics: Antineoplastic Agents; Blotting, Northern; Cell Division; Colonic Neoplasms; Cytokines; Depression, Chemical; Drug Synergism; Enzyme Induction; Floxuridine; Fluorouracil; Humans; Interferon-gamma; Interleukin-1; RNA, Messenger; Stomach Neoplasms; Thymidine Phosphorylase; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	1993
[Combination therapy of high dose doxifluridine (5'-DFUR)+mitomycin C (MMC) for advanced or recurrent colorectal cancer. Joint Research Group in the Osaka Area for Combination Therapy of 5'-DFUR with Other Drugs]. Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:1 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Follow-Up Studies; Humans; Injections, Intravenous; Male; Middle Aged; Mitomycin; Neoplasm Recurrence, Local; Rectal Neoplasms; Survival Rate	1993
Cytokines induce uridine phosphorylase in mouse colon 26 carcinoma cells and make the cells more susceptible to 5'-deoxy-5-fluorouridine. Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:3 Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Cytokines; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Fibroblast Growth Factor 2; Floxuridine; Fluorouracil; Interferon-gamma; Interleukin-1; Mice; RNA, Neoplasm; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Uridine; Uridine Phosphorylase	1993
[A case of recurrent colon cancer treated markedly effective with 5'-DFUR]. Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:8 Topics: Administration, Oral; Aged; Antineoplastic Agents; Colonic Neoplasms; Floxuridine; Humans; Liver Neoplasms; Lymphatic Metastasis; Male	1993
[A case of effective chemotherapy by combination of 5'-DFUR and MMC for recurrent colon cancer with multiple liver metastasis]. Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:8 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Colonic Neoplasms; Drug Administration Schedule; Floxuridine; Humans; Liver Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Middle Aged; Mitomycin; Postoperative Period	1996
Antitumor effects of 5'-deoxy-5-fluorouridine in combination with recombinant human interleukin 2 on murine colon carcinoma 26. Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:3 Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Colonic Neoplasms; Drug Therapy, Combination; Female; Floxuridine; Humans; Interleukin-2; Isomerism; Mice; Mice, Inbred BALB C; Recombinant Proteins	1997
Inhibitory effects of fluorinated pyrimidines, 5'-DFUR, UFT and T-506, in a model of hepatic metastasis of mouse colon 26 adenocarcinoma-assessment of inhibitory activity and adverse reactions at the maximum tolerated dose. Clinical & experimental metastasis, 1997, Volume: 15, Issue:3 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Body Weight; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Combinations; Female; Floxuridine; Fluorodeoxyuridylate; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Tegafur; Uracil	1997
[Effect on 5'-deoxy-5-fluorouridine (5'-DFUR) of pyrimidine nucleoside phosphorylase (PyNPase), matrix metalloprotease and serum IAP values. Hokuriku Colorectal Cancer Chemotherapy Study Group]. Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:13 Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Extracellular Matrix; Female; Floxuridine; Humans; Lymphatic Metastasis; Male; Metalloendopeptidases; Middle Aged; Neoplasm Invasiveness; Neoplasm Proteins; Pentosyltransferases; Pyrimidine Phosphorylases; Rectal Neoplasms	1997
Enhancement of 5-fluorouracil cytotoxicity by human thymidine-phosphorylase expression in cancer cells: in vitro and in vivo study. International journal of cancer, 1999, Jan-29, Volume: 80, Issue:3 Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma; Colonic Neoplasms; Drug Synergism; Floxuridine; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Thymidine Phosphorylase; Transfection	1999
[Comparative study of 5'-deoxy-5-fluorouridine between older cancer patients versus younger cancer patients]. Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:4 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Humans; Male; Middle Aged; Stomach Neoplasms	1999
Enhancement of the anti-tumor effect of 5'-deoxy-5-fluorouridine by transfection of thymidine phosphorylase gene into human colon cancer cells. Japanese journal of cancer research : Gann, 1999, Volume: 90, Issue:4 Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Feasibility Studies; Floxuridine; Genetic Therapy; Humans; Mice; Mice, Nude; Thymidine Phosphorylase; Transfection; Tumor Cells, Cultured	1999
Effect of a fluorinated pyrimidine on cachexia and tumour growth in murine cachexia models: relationship with a proteolysis inducing factor. British journal of cancer, 2000, Volume: 83, Issue:1 Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Appetite Stimulants; Blood Proteins; Body Weight; Cachexia; Clone Cells; Colonic Neoplasms; Female; Floxuridine; Humans; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Nude; Muscle Proteins; Neoplasm Proteins; Neoplasm Transplantation; Proteoglycans; Transplantation, Heterologous; Tumor Cells, Cultured; Uterine Cervical Neoplasms	2000
[A patient with multiple pulmonary metastases from colonic cancer who survived for 5 years by effectual administration of 5'-DFUR]. Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:7 Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Carcinoembryonic Antigen; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Humans; Lung Neoplasms	2000
[Weekly low dose CPT-11 for multiple lung metastases of colon cancer on an out-patient treatment: a case report]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2001, Volume: 98, Issue:2 Topics: Adult; Ambulatory Care; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Humans; Irinotecan; Lung Neoplasms	2001
Impact of thymidine phosphorylase surexpression on fluoropyrimidine activity and on tumour angiogenesis. British journal of cancer, 2001, Aug-03, Volume: 85, Issue:3 Topics: Animals; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Resistance, Neoplasm; Floxuridine; Fluorouracil; Formazans; Neoplasm Transplantation; Neovascularization, Pathologic; Pentosyltransferases; Pyrimidine Phosphorylases; Rats; Tetrazolium Salts; Thymidine Phosphorylase; Transfection; Tumor Cells, Cultured	2001
[A case of lung metastasis from colon cancer treated successfully with combined chemotherapy of CPT-11 and 5'-DFUR]. Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:12 Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Middle Aged	2001
gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor. Angiogenesis, 2001, Volume: 4, Issue:3 Topics: Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Carcinoma; Carcinoma, Renal Cell; Chemotaxis; Colonic Neoplasms; DNA Replication; Drug Combinations; Endothelial Growth Factors; Endothelium, Vascular; Female; Fibroblast Growth Factor 2; Floxuridine; Fluorouracil; Humans; Intercellular Signaling Peptides and Proteins; Kidney Neoplasms; Lung Neoplasms; Lymphokines; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Neoplasm Proteins; Neovascularization, Pathologic; Prodrugs; Prostheses and Implants; Recombinant Proteins; Sodium Oxybate; Stomach Neoplasms; Tegafur; Tumor Cells, Cultured; Uracil; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Xenograft Model Antitumor Assays	2001
Overexpression of pyrimidine nucleoside phosphorylase enhances the sensitivity to 5'-deoxy-5-fluorouridine in tumour cells in vitro and in vivo. European journal of cancer (Oxford, England : 1990), 2002, Volume: 38, Issue:5 Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Cell Survival; Colonic Neoplasms; Combined Modality Therapy; DNA, Complementary; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Floxuridine; Fluorouracil; Genetic Therapy; Humans; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Pentosyltransferases; Prodrugs; Pyrimidine Phosphorylases; Transfection; Tumor Cells, Cultured	2002
[A case of colon cancer with multiple liver metastases and lymph nodes metastases successfully treated by 5'-deoxy-5-fluorouridine]. Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:6 Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Administration Schedule; Floxuridine; Hepatectomy; Humans; Liver Neoplasms; Lymphatic Metastasis; Male	2002
Effect of folinic acid on fluorouracil activity and expression of thymidylate synthase. Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3 Topics: Animals; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Leucovorin; Mice; Mice, Inbred BALB C; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured; Uridine Monophosphate	1992
Anticachectic activity of 5'-deoxy-5-fluorouridine in a murine tumor cachexia model, colon 26 adenocarcinoma. Cancer research, 1990, Aug-01, Volume: 50, Issue:15 Topics: Acute-Phase Proteins; Adenocarcinoma; Animals; Antineoplastic Agents; Biomarkers, Tumor; Cachexia; Colonic Neoplasms; Floxuridine; Isomerism; Male; Mice; Mice, Inbred Strains	1990
[5-fluorouracil concentration in gastroenterological tumor tissues, in adjacent normal tissues, and in serum after preoperative oral administration of 5'-deoxy-5-fluorouridine (5'-DFUR)]. Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:3 Topics: Administration, Oral; Colonic Neoplasms; Floxuridine; Fluorouracil; Gallbladder Neoplasms; Humans; Stomach Neoplasms	1991
[5-Fluorouracil level and pyrimidine nucleoside phosphorylase activity in cancer patients after oral administration of doxifluridine (5'-DFUR)]. Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:6 Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Colonic Neoplasms; Enzyme Activation; Female; Floxuridine; Fluorouracil; Humans; Male; Middle Aged; Pentosyltransferases; Pyrimidine Phosphorylases; Stomach Neoplasms	1991
[Antitumor activity of T-506, a novel synthetic FUDR derivative, on murine colon cancer and its hepatic metastasis]. Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:8 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Floxuridine; Fluorodeoxyuridylate; Liver Neoplasms; Mice; Mice, Inbred BALB C; Tegafur; Uracil	1991
[A case of pulmonary metastasis from colon cancer responding completely to high-dose 5'-DFUR plus MMC combination chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:13 Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Humans; Infusions, Intravenous; Lung Neoplasms; Mitomycin	1991
5'-Deoxy-5-fluorouridine improves cachexia by a mechanism independent of its antiproliferative action in colon 26 adenocarcinoma-bearing mice. Cancer chemotherapy and pharmacology, 1991, Volume: 29, Issue:1 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cachexia; Cell Division; Colonic Neoplasms; Drug Resistance; Drug Screening Assays, Antitumor; Floxuridine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasm Transplantation; Time Factors; Tumor Cells, Cultured	1991
Optimal treatment regimens for 5'-deoxy-5-fluorouridine, with or without (E)-5-(2-bromovinyl)-2'-deoxyuridine, against various tumors in mice. Japanese journal of cancer research : Gann, 1990, Volume: 81, Issue:4 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antiviral Agents; Bromodeoxyuridine; Colonic Neoplasms; Drug Therapy, Combination; Floxuridine; Fluorouracil; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Inbred BALB C; Pentosyltransferases; Prodrugs; Pyrimidine Phosphorylases	1990
[Study of tissue drug concentration of fluorinated pyrimidine anticancer drugs--comparison of 5'DFUR and UFT]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:9 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colon; Colonic Neoplasms; Drug Administration Schedule; Floxuridine; Humans; Lymph Nodes; Tegafur; Uracil	1990
Kinetic analysis of 5-fluorouracil action against various cancer cells. Japanese journal of cancer research : Gann, 1990, Volume: 81, Issue:10 Topics: Animals; Antineoplastic Agents; Cell Cycle; Colonic Neoplasms; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Humans; Kidney Neoplasms; Leukemia P388; Mice; RNA, Ribosomal; S Phase; Time Factors; Uridine	1990
[A study on pre-operative administration of 5'-DFUR in carcinomas of the gastric, breast, thyroid and colon]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:12 Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Colonic Neoplasms; Combined Modality Therapy; Female; Floxuridine; Fluorouracil; Humans; Lymph Nodes; Pentosyltransferases; Preoperative Care; Pyrimidine Phosphorylases; Stomach Neoplasms; Thyroid Neoplasms; Tissue Distribution	1990
Enhanced therapeutic efficacy of 5'deoxy-5-fluorouridine in 5-fluorouracil resistant head and neck tumours in relation to 5-fluorouracil metabolising enzymes. British journal of cancer, 1989, Volume: 59, Issue:3 Topics: Animals; Antineoplastic Agents; Carcinoma; Colonic Neoplasms; Drug Resistance; Female; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Isomerism; Mice; Mice, Nude; Neoplasm Transplantation; Pentosyltransferases; Pyrimidine Phosphorylases	1989
Enhanced antitumor effect of 5'-deoxy-5-fluorouridine by oral administration with L-cysteine. Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:2 Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cysteine; Drug Synergism; Floxuridine; Fluorouracil; Humans; Injections, Intravenous; Lung Neoplasms; Male; Mice	1989
[Two cases of gastrointestinal cancers with major responses to sequential methotrexate 5-FU plus 5'-DFUR]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:5 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Stomach Neoplasms	1989
[A study of combined chemotherapy with MMC, ADM, CDDP, VP-16 and 5'DFUR (MAC-VD) in advanced cancers of digestive organs]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:7 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Floxuridine; Gallbladder Neoplasms; Humans; Infusions, Intravenous; Male; Middle Aged; Mitomycin; Mitomycins; Splenic Neoplasms; Stomach Neoplasms	1989
Comparative antitumor activity of 5-fluorouracil and 5'-deoxy-5-fluorouridine in combination with radiation therapy in mice bearing colon 26 adenocarcinoma. Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:6 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bone Marrow; Colonic Neoplasms; Combined Modality Therapy; Female; Floxuridine; Fluorouracil; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Spleen; Thymus Gland; Weight Gain	1989
Phase I-II trial of doxifluridine (5'DFUR) administered as long-term continuous infusion using a portable infusion pump for advanced colorectal cancer. European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:11 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Drug Evaluation; Female; Floxuridine; Humans; Infusion Pumps; Isomerism; Male; Middle Aged; Rectal Neoplasms; Time Factors	1989
Fluoropyrimidine metabolism in human head and neck cancer xenografts and murine colon tumors. Advances in experimental medicine and biology, 1989, Volume: 253B Topics: Animals; Colonic Neoplasms; Drug Screening Assays, Antitumor; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Mice; Neoplasm Transplantation; Orotate Phosphoribosyltransferase; Pentosyltransferases; Pyrimidine Phosphorylases; Tumor Cells, Cultured	1989
[Phase I study of 5'-deoxy-5-fluorouridine (5'-DFUR)]. Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:10 Topics: Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Agents; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Floxuridine; Humans; Leukocyte Count; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasms	1985
[Phase II study of 5'-deoxy-5-fluorouridine (5'-DFUR) in patients with malignant cancer--a multi-institutional cooperative study]. Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:10 Topics: Anorexia; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Diarrhea; Drug Administration Schedule; Drug Evaluation; Female; Floxuridine; Humans; Leukopenia; Male; Nausea; Neoplasms; Stomach Neoplasms	1985
[Phase II study of 5'-DFUR in gastrointestinal and breast cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:11 Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Diarrhea; Drug Administration Schedule; Drug Evaluation; Female; Floxuridine; Humans; Leukopenia; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Nausea; Rectal Neoplasms; Stomach Neoplasms	1985
[Phase II study of 5'-DFUR (5'-deoxy-5-fluorouridine) by the Cooperative Study Group]. Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:11 Topics: Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Diarrhea; Drug Administration Schedule; Drug Evaluation; Female; Floxuridine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nausea; Neoplasms; Rectal Neoplasms; Stomach Neoplasms	1985
Phase II clinical evaluation of doxifluridine. Cancer treatment reports, 1986, Volume: 70, Issue:6 Topics: Adult; Aged; Alopecia; Antineoplastic Agents; Breast Neoplasms; Central Nervous System Diseases; Colonic Neoplasms; Drug Evaluation; Female; Floxuridine; Heart Diseases; Hematologic Diseases; Humans; Infusions, Parenteral; Kidney Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Nausea; Neoplasms; Rectal Neoplasms	1986
Noninvasive fluorine-19 NMR study of fluoropyrimidine metabolism in cell cultures of human pancreatic and colon adenocarcinoma. Cancer chemotherapy and pharmacology, 1986, Volume: 18, Issue:1 Topics: Adenocarcinoma; Cells, Cultured; Colonic Neoplasms; Floxuridine; Fluorine; Fluorouracil; Humans; Macromolecular Substances; Magnetic Resonance Spectroscopy; Pancreatic Neoplasms; Spectrum Analysis	1986
[Clinical trial of 5'-deoxy-5-fluorouridine in malignant tumors under cooperative study (phase II study)]. Nihon Gan Chiryo Gakkai shi, 1986, Jun-20, Volume: 21, Issue:5 Topics: Aged; Aged, 80 and over; Breast Neoplasms; Colonic Neoplasms; Drug Evaluation; Female; Floxuridine; Humans; Lung Neoplasms; Male; Rectal Neoplasms; Stomach Neoplasms	1986
Toxicity and antitumor effect of 5-fluorouracil and its rescue by uridine. Advances in experimental medicine and biology, 1986, Volume: 195 Pt B Topics: Animals; Body Temperature Regulation; Carcinoma; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Floxuridine; Fluorouracil; Hematopoiesis; Leukocyte Count; Mice; Uridine	1986
[Combination chemotherapy of human gastrointestinal and breast cancer xenografts in nude mice with 5'-deoxy-5-fluorouridine and mitomycin C]. Nihon Gan Chiryo Gakkai shi, 1986, Aug-20, Volume: 21, Issue:7 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Female; Floxuridine; Humans; Male; Mice; Mice, Nude; Mitomycin; Mitomycins; Neoplasm Transplantation; Stomach Neoplasms	1986
Role of administration route in the therapeutic efficacy of doxifluridine. Journal of the National Cancer Institute, 1987, Volume: 78, Issue:3 Topics: Administration, Oral; Animals; Biological Availability; Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Infusions, Intravenous; Injections, Intravenous; Kinetics; Neoplasm Transplantation; Rats; Rats, Inbred F344	1987
[Combination chemotherapy with 3 or 4 drugs on human breast and gastrointestinal cancer xenografts in nude mice (II)]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:5 Pt 1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Colonic Neoplasms; Cyclophosphamide; Doxorubicin; Female; Floxuridine; Fluorouracil; Humans; Methotrexate; Mice; Mice, Nude; Mitomycin; Mitomycins; Neoplasm Transplantation; Stomach Neoplasms; Tegafur; Vindesine	1987
[Effects of alternating chemotherapy with 2 non-cross-resistant drug combinations on human alimentary and breast cancer xenografts in nude mice]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:5 Pt 1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Humans; Male; Mice; Mice, Nude; Mitomycin; Mitomycins; Neoplasm Transplantation; Pancreatic Neoplasms; Vindesine	1987
Comparative antitumor activity of ruthenium derivatives with 5'-deoxy-5-fluorouridine in chemically induced colorectal tumors in SD rats. Cancer chemotherapy and pharmacology, 1987, Volume: 19, Issue:4 Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylnitrosamine; Floxuridine; Imidazoles; Male; Organometallic Compounds; Rats; Rats, Inbred Strains; Rectal Neoplasms; Ruthenium	1987
Excretion of doxifluridine catabolites in human bile assessed by 19F NMR spectrometry. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1987, Volume: 41, Issue:2 Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Bile; Colonic Neoplasms; Floxuridine; Humans; Magnetic Resonance Spectroscopy; Male	1987
[Antitumor effects of 5'-deoxy-5-fluorouridine (5'-DFUR) against various murine tumors in combination with recombinant interferon alpha or cytostatics]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:12 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Floxuridine; Interferon Type I; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Recombinant Proteins	1987
[Comparative studies on the antitumor activity of the fluorinated pyrimidines 5'-DFUR, tegafur, UFT and FUra on various murine tumors]. Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:5 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Floxuridine; Fluorouracil; Leukemia P388; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Neoplasms, Experimental; Sarcoma 180; Tegafur; Uracil	1988
Comparison of the pyrimidine nucleoside phosphorylase activity in human tumors and normal tissues. Experimental pathology, 1988, Volume: 33, Issue:1 Topics: Colonic Neoplasms; Floxuridine; Fluorouracil; Humans; In Vitro Techniques; Pentosyltransferases; Prodrugs; Pyrimidine Phosphorylases; Spectrophotometry; Stomach Neoplasms	1988
Inhibition of thymidylate synthase after administration of doxifluridine in a transplantable colon carcinoma in the rat. Cancer investigation, 1988, Volume: 6, Issue:4 Topics: Animals; Carcinoma; Colonic Neoplasms; Female; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Male; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Thymidylate Synthase	1988
Neurological manifestations in a phase 2 study of 13 patients treated with doxyfluridine. Acta neurologica Scandinavica, 1985, Volume: 72, Issue:2 Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Body Weight; Brain Diseases; Cerebellar Diseases; Colonic Neoplasms; Female; Floxuridine; Humans; Middle Aged; Nervous System Diseases; Peripheral Nervous System Diseases; Rectal Neoplasms	1985
[Clinical phase II study of 5'-DFUR for cancer of the digestive organs by a cooperative study group]. Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:12 Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Floxuridine; Humans; Male; Middle Aged; Stomach Neoplasms	1985