doxepin has been researched along with Xerostomia in 7 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Xerostomia: Decreased salivary flow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fluoxetine was compared to doxepin in geriatric out-patients with major depressive illness." | 6.66 | Double-blind comparative trials of fluoxetine and doxepin in geriatric patients with major depressive disorder. ( Cohn, JB; Feighner, JP, 1985) |
| "After a 1-week placebo washout, 25 depressed hospitalized patients were treated for 4 weeks with trimipramine or doxepin in a fixed equivalent dosage schedule ending in 150 mg h." | 2.66 | A comparative trial of the antidepressant, anxiolytic, and cardiovascular effects of trimipramine and doxepin in depressed hospitalized patients. ( Assalian, P; Phillips, R; Rosengarten, MD, 1985) |
| "Fluoxetine was compared to doxepin in geriatric out-patients with major depressive illness." | 2.66 | Double-blind comparative trials of fluoxetine and doxepin in geriatric patients with major depressive disorder. ( Cohn, JB; Feighner, JP, 1985) |
| " A significant positive correlation was obtained between dosage and blood levels of maprotiline and doxepin, but there was no correlation between blood levels and clinical response." | 2.65 | Therapeutic superiority of maprotiline versus doxepin in geriatric depression. ( Ahles, S; DeMet, E; Gwirtsman, HE; Halaris, A; Hill, MA, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gwirtsman, HE | 1 |
| Ahles, S | 1 |
| Halaris, A | 1 |
| DeMet, E | 1 |
| Hill, MA | 1 |
| Rickels, K | 2 |
| Csanalosi, I | 1 |
| Werblowsky, J | 1 |
| Weise, CC | 1 |
| Weinstock, R | 1 |
| Brown, AS | 1 |
| Winokur, A | 1 |
| Von Poelnitz, M | 1 |
| Guy, W | 1 |
| Ban, TA | 1 |
| McEvoy, JP | 1 |
| Petrie, WM | 1 |
| Wilson, WH | 1 |
| Schaffer, JD | 1 |
| Hetland, L | 1 |
| Woie, L | 1 |
| Assalian, P | 1 |
| Rosengarten, MD | 1 |
| Phillips, R | 1 |
| Feighner, JP | 2 |
| Smith, WT | 1 |
| Cohn, JB | 1 |
6 trials available for doxepin and Xerostomia
| Article | Year |
|---|---|
Therapeutic superiority of maprotiline versus doxepin in geriatric depression.
Topics: Anthracenes; Clinical Trials as Topic; Constipation; Depressive Disorder; Dizziness; Double-Blind Me | 1983 |
Amitriptyline-perphenazine and doxepin in depressed outpatients: a controlled double-blind study.
Topics: Adult; Ambulatory Care; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind M | 1982 |
A collaborative study of a new antidepressant, viloxazine, in neurotic and endogenous depressives.
Topics: Adolescent; Adult; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Dizziness; Doxepin; | 1982 |
A comparative trial of the antidepressant, anxiolytic, and cardiovascular effects of trimipramine and doxepin in depressed hospitalized patients.
Topics: Anorexia; Anti-Anxiety Agents; Clinical Trials as Topic; Depressive Disorder; Dibenzazepines; Dizzin | 1985 |
Alprazolam, amitriptyline, doxepin, and placebo in the treatment of depression.
Topics: Adult; Alcoholism; Alprazolam; Ambulatory Care; Amitriptyline; Anti-Anxiety Agents; Benzodiazepines; | 1985 |
Double-blind comparative trials of fluoxetine and doxepin in geriatric patients with major depressive disorder.
Topics: Age Factors; Aged; Anxiety; Blood Pressure; Body Weight; Clinical Trials as Topic; Depressive Disord | 1985 |
1 other study available for doxepin and Xerostomia
| Article | Year |
|---|---|
[Diseases of teeth, periodontium and oral mucosa as side effects of anticholinergic drugs].
Topics: Adult; Dental Caries; Doxepin; Female; Gingival Diseases; Humans; Male; Methotrimeprazine; Middle Ag | 1975 |