doxepin has been researched along with Weight Gain in 3 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Weight Gain: Increase in BODY WEIGHT over existing weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although these clinical actions are classically attributed to blockade of the H1 receptor, recent findings with H1 selective agents and H1 selective dosing of older agents are challenging these notions and suggest that some of the clinical limitations of current H1-blocking agents at their currently utilized doses could be attributable to other properties of these drugs, especially to their simultaneous actions on muscarinic, cholinergic, and adrenergic receptors." | 2.44 | Selective histamine H1 antagonism: novel hypnotic and pharmacologic actions challenge classical notions of antihistamines. ( Stahl, SM, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stahl, SM | 1 |
| Sachs, DP | 1 |
| Leischow, SJ | 1 |
| Edwards, NB | 1 |
| Murphy, JK | 1 |
| Downs, AD | 1 |
| Ackerman, BJ | 1 |
| Rosenthal, TL | 1 |
2 reviews available for doxepin and Weight Gain
| Article | Year |
|---|---|
Selective histamine H1 antagonism: novel hypnotic and pharmacologic actions challenge classical notions of antihistamines.
Topics: Doxepin; Histamine Antagonists; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Hu | 2008 |
Pharmacologic approaches to smoking cessation.
Topics: Clonidine; Doxepin; Humans; Nicotine; Smoking; Smoking Cessation; Weight Gain | 1991 |
1 trial available for doxepin and Weight Gain
| Article | Year |
|---|---|
Doxepin as an adjunct to smoking cessation: a double-blind pilot study.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Doxepin; Drug Administration Schedule; Humans; | 1989 |