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doxepin and Tourette Syndrome

doxepin has been researched along with Tourette Syndrome in 1 studies

Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.

Tourette Syndrome: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rzesnitzek, L1
Wächter, T1
Krüger, R1
Gharabaghi, A1
Plewnia, C1

Other Studies

1 other study available for doxepin and Tourette Syndrome

ArticleYear
Suppression of extrapyramidal side effects of doxepin by thalamic deep brain stimulation for Tourette syndrome.
    Neurology, 2011, Nov-01, Volume: 77, Issue:18

    Topics: Adult; Antidepressive Agents, Tricyclic; Deep Brain Stimulation; Doxepin; Humans; Male; Tourette Syn

2011