doxepin has been researched along with Thrombopenia in 1 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 46-year-old man suffering from neurotic depression complicated by alcohol and benzodiazepine dependence developed Coombs'-positive hemolytic anemia and thrombocytopenia with acute renal failure after 5 weeks of monotherapy with doxepin at a final dosage of 100 mg daily." | 7.67 | A case of immune complex hemolytic anemia, thrombocytopenia, and acute renal failure associated with doxepin use. ( Conradty, M; Grohmann, R; Londong, V; Rüther, E; Witzgall, H; Wolf, B, 1989) |
| "A 46-year-old man suffering from neurotic depression complicated by alcohol and benzodiazepine dependence developed Coombs'-positive hemolytic anemia and thrombocytopenia with acute renal failure after 5 weeks of monotherapy with doxepin at a final dosage of 100 mg daily." | 3.67 | A case of immune complex hemolytic anemia, thrombocytopenia, and acute renal failure associated with doxepin use. ( Conradty, M; Grohmann, R; Londong, V; Rüther, E; Witzgall, H; Wolf, B, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wolf, B | 1 |
| Conradty, M | 1 |
| Grohmann, R | 1 |
| Rüther, E | 1 |
| Witzgall, H | 1 |
| Londong, V | 1 |
1 other study available for doxepin and Thrombopenia
| Article | Year |
|---|---|
A case of immune complex hemolytic anemia, thrombocytopenia, and acute renal failure associated with doxepin use.
Topics: Acute Kidney Injury; Anemia, Hemolytic, Autoimmune; Depressive Disorder; Doxepin; Humans; Male; Midd | 1989 |