doxepin has been researched along with Tachycardia, Ventricular in 3 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vorinostat is a histone deacetylase inhibitor used in the treatment of recurrent or persistent cases of cutaneous T-cell lymphoma (CTCL)." | 4.88 | QT interval prolongation and torsades de pointes in a patient undergoing treatment with vorinostat: a case report and review of the literature. ( Lynch, DR; Newby, LK; Washam, JB, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, XY | 1 |
| Song, XT | 1 |
| Zhang, Y | 1 |
| Lynch, DR | 1 |
| Washam, JB | 1 |
| Newby, LK | 1 |
| Diltoer, MW | 1 |
| Poelmans, LW | 1 |
| Hubloue, I | 1 |
| Spapen, HD | 1 |
| Maes, V | 1 |
| Huyghens, LP | 1 |
1 review available for doxepin and Tachycardia, Ventricular
| Article | Year |
|---|---|
QT interval prolongation and torsades de pointes in a patient undergoing treatment with vorinostat: a case report and review of the literature.
Topics: Antineoplastic Agents; Doxepin; Electrocardiography; Histone Deacetylase Inhibitors; Humans; Hydroxa | 2012 |
2 other studies available for doxepin and Tachycardia, Ventricular
| Article | Year |
|---|---|
Wide QRS Complex Tachycardia With a Dominant R-Wave in Lead aVR-Is It Ventricular Tachycardia?
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Diagnosis, Differential; Doxepin; Drug Overdose; El | 2020 |
Combined intoxication with a tricyclic antidepressive agent and a neuroleptic.
Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Blood Gas Analysis; Doxepin; Drug Syn | 1996 |