doxepin has been researched along with Symptom Cluster in 7 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this review is to present relatively detailed information on the characteristics of tricyclic antidepressants, mainly amitriptyline hydrochloride and doxepin hydrochloride, for use as an integral part of the safe and effective management of fibromyalgia and, to a lesser extent, other chronic pain syndromes." | 4.79 | A guide to the understanding and use of tricyclic antidepressants in the overall management of fibromyalgia and other chronic pain syndromes. ( Godfrey, RG, 1996) |
| "Aromatic anticonvulsant agents such as carbamazepine and phenytoin can induce anticonvulsant hypersensitivity syndrome (AHS) at a frequency of 1 in 10,000 to 1 in 1,000 treated patients." | 3.73 | Anticonvulsant hypersensitivity syndrome: cross-reactivity with tricyclic antidepressant agents. ( Bröcker, EB; Pfeuffer, P; Raith, P; Seitz, CS; Trautmann, A, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Walloch, JE | 1 |
| Klauwer, C | 1 |
| Lanczik, M | 1 |
| Brockington, IF | 1 |
| Kornhuber, J | 1 |
| Seitz, CS | 1 |
| Pfeuffer, P | 1 |
| Raith, P | 1 |
| Bröcker, EB | 1 |
| Trautmann, A | 1 |
| Lindsay, PG | 1 |
| Wyckoff, M | 1 |
| Godfrey, RG | 1 |
| Granacher, RP | 1 |
| Baldessarini, RJ | 1 |
| Cunha, UV | 1 |
| Holowiecki, J | 1 |
| Hese, R | 1 |
| Stella, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Internet-Enhanced Management of Fibromyalgia[NCT00423631] | 118 participants (Actual) | Interventional | 2006-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for doxepin and Symptom Cluster
| Article | Year |
|---|---|
Delusional denial of pregnancy as a special form of Cotard's syndrome: case report and review of the literature.
Topics: Adrenergic Uptake Inhibitors; Antipsychotic Agents; Delusions; Denial, Psychological; Doxepin; Femal | 2007 |
A guide to the understanding and use of tricyclic antidepressants in the overall management of fibromyalgia and other chronic pain syndromes.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chronic Disease; Doxepin; Fibromyalgia; Humans; Lif | 1996 |
5 other studies available for doxepin and Symptom Cluster
| Article | Year |
|---|---|
Anticonvulsant hypersensitivity syndrome: cross-reactivity with tricyclic antidepressant agents.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Anticonvulsants; Antidepressive A | 2006 |
The depression-pain syndrome and its response to antidepressants.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Depression; Desipramine; Doxepin; Fem | 1981 |
Physostigmine. Its use in acute anticholinergic syndrome with antidepressant and antiparkinson drugs.
Topics: Acute Disease; Adult; Amitriptyline; Benztropine; Chemical Phenomena; Chemistry; Cholinesterase Inhi | 1975 |
Antidepressants: their uses in nonpsychiatric disorders of aging.
Topics: Affective Symptoms; Aged; Antidepressive Agents; Chronic Disease; Colonic Diseases, Functional; Depr | 1986 |
[Effectiveness of Sinequan (Doxepin) in the treatment of neurotic and pseudoneurotic syndromes].
Topics: Adolescent; Adult; Aged; Doxepin; Drug Evaluation; Female; Humans; Male; Middle Aged; Neurotic Disor | 1974 |