Page last updated: 2024-10-26

doxepin and Schizophrenia

doxepin has been researched along with Schizophrenia in 12 studies

Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
" A high proportion of affective disorders has been found among opioid-dependent patients; these are responsive to psychotherapy and to antidepressant treatment with doxepin."3.67Psychiatric disorders in opioid-dependent patients. ( McLellan, AT; O'Brien, CP; Woody, GE, 1984)
"Doctors' prescription and dosing behaviour was investigated using data from 9 clinical trials in 550 patients treated with psychotropics."1.29Correct titration of non-drugs and some other methodological issues. ( Beneke, M; Fritze, J; Rasmus, W; Rød, IS, 1994)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's2 (16.67)18.2507
2000's3 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Härtter, S1
Connemann, B1
Schönfeldt-Lecuona, C1
Sachse, J1
Hiemke, C1
Iwabuchi, K1
Ito, C1
Tashiro, M1
Kato, M1
Kano, M1
Itoh, M1
Iwata, R1
Matsuoka, H1
Sato, M1
Yanai, K1
Walloch, JE1
Klauwer, C1
Lanczik, M1
Brockington, IF1
Kornhuber, J1
O'Brien, CP1
Woody, GE1
McLellan, AT1
Falterman, CG1
Richardson, CJ1
Beneke, M1
Rasmus, W1
Rød, IS1
Fritze, J1
Diltoer, MW1
Poelmans, LW1
Hubloue, I1
Spapen, HD1
Maes, V1
Huyghens, LP1
Ketai, R1
Woggon, B1
Angst, J1
Ayd, FJ1
Ciurezu, T1
Timofte, G1
Murphy, HB1

Reviews

1 review available for doxepin and Schizophrenia

ArticleYear
Delusional denial of pregnancy as a special form of Cotard's syndrome: case report and review of the literature.
    Psychopathology, 2007, Volume: 40, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Antipsychotic Agents; Delusions; Denial, Psychological; Doxepin; Femal

2007

Trials

1 trial available for doxepin and Schizophrenia

ArticleYear
[Activity profile of carpipramine. Results of an open trial and a double-blind trial versus doxepin].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:12

    Topics: Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzodiazepines; Clinic

1976

Other Studies

10 other studies available for doxepin and Schizophrenia

ArticleYear
Elevated quetiapine serum concentrations in a patient treated concomitantly with doxepin, lorazepam, and pantoprazole.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agen

2004
Histamine H1 receptors in schizophrenic patients measured by positron emission tomography.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2005, Volume: 15, Issue:2

    Topics: Adult; Analysis of Variance; Brain; Doxepin; Humans; Male; Positron-Emission Tomography; Protein Bin

2005
Psychiatric disorders in opioid-dependent patients.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:12 Pt 2

    Topics: Counseling; Doxepin; Humans; Interview, Psychological; Mental Disorders; Mood Disorders; Opioid-Rela

1984
Small left colon syndrome associated with maternal ingestion of psychotropic drugs.
    The Journal of pediatrics, 1980, Volume: 97, Issue:2

    Topics: Benztropine; Biperiden; Chlorpromazine; Colonic Diseases, Functional; Doxepin; Female; Humans; Infan

1980
Correct titration of non-drugs and some other methodological issues.
    Neuropsychobiology, 1994, Volume: 30, Issue:1

    Topics: Administration, Oral; Amitriptyline; Anxiety Disorders; Benperidol; Depressive Disorder; Dose-Respon

1994
Combined intoxication with a tricyclic antidepressive agent and a neuroleptic.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 1996, Volume: 3, Issue:1

    Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Blood Gas Analysis; Doxepin; Drug Syn

1996
High-dosage and versatile drug therapy with treatment-resistant psychotic patients.
    Hospital & community psychiatry, 1976, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Chlorpromazine; Doxepin; Female; Hospitals, Psychiatric; Hu

1976
Maintenance doxepin (sinequan) therapy for depressive illness.
    Diseases of the nervous system, 1975, Volume: 36, Issue:3

    Topics: Adult; Aged; Bipolar Disorder; Chemical and Drug Induced Liver Injury; Chronic Disease; Depression;

1975
Doxepine therapy in outpatients with depressive anxious states.
    Revue roumaine de medecine (1974), 1974, Volume: 12, Issue:2

    Topics: Adjustment Disorders; Adult; Anxiety Disorders; Doxepin; Female; Humans; Male; Mental Disorders; Mid

1974
Differences between mental disorders of French Canadians and British Canadians.
    Canadian Psychiatric Association journal, 1974, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Alcoholism; Bipolar Disorder; Canada; Chlordiazepoxide; Cranio

1974
chemdatabank.com