doxepin has been researched along with Poisoning in 3 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Suicidal self-poisoning with tricyclic antidepressants like doxepin is a major therapeutic problem in emergency medicine with a high fatality rate." | 3.70 | Is there a role for hemoperfusion/hemodialysis as a treatment option in severe tricyclic antidepressant intoxication? ( Frank, RD; Kierdorf, HP, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diltoer, MW | 1 |
| Poelmans, LW | 1 |
| Hubloue, I | 1 |
| Spapen, HD | 1 |
| Maes, V | 1 |
| Huyghens, LP | 1 |
| Frank, RD | 1 |
| Kierdorf, HP | 1 |
| Norheim, G | 1 |
3 other studies available for doxepin and Poisoning
| Article | Year |
|---|---|
Combined intoxication with a tricyclic antidepressive agent and a neuroleptic.
Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Blood Gas Analysis; Doxepin; Drug Syn | 1996 |
Is there a role for hemoperfusion/hemodialysis as a treatment option in severe tricyclic antidepressant intoxication?
Topics: Adult; Antidepressive Agents, Tricyclic; Doxepin; Heart Arrest; Hemoperfusion; Humans; Male; Poisoni | 2000 |
Determination of doxepin in autopsy material.
Topics: Adult; Autopsy; Chromatography, Gas; Chromatography, Thin Layer; Doxepin; Female; Humans; Liver; Mas | 1973 |