doxepin has been researched along with Peripheral Nerve Diseases in 4 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Overall pain was significantly reduced by doxepin, capsaicin and doxepin/capsaicin to a similar extent." | 9.09 | Topical application of doxepin hydrochloride, capsaicin and a combination of both produces analgesia in chronic human neuropathic pain: a randomized, double-blind, placebo-controlled study. ( McCleane, G, 2000) |
| "Overall pain was significantly reduced by doxepin, capsaicin and doxepin/capsaicin to a similar extent." | 5.09 | Topical application of doxepin hydrochloride, capsaicin and a combination of both produces analgesia in chronic human neuropathic pain: a randomized, double-blind, placebo-controlled study. ( McCleane, G, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dworsky, ZD | 1 |
| Bennett, R | 1 |
| Kim, JM | 1 |
| Kuo, DJ | 1 |
| Şavk, E | 1 |
| McCleane, G | 1 |
| Paladini, VA | 1 |
| Battigelli, D | 1 |
| Antonaglia, V | 1 |
| Benvegnù, M | 1 |
| Longo, A | 1 |
| Mocavero, G | 1 |
1 review available for doxepin and Peripheral Nerve Diseases
| Article | Year |
|---|---|
Neurologic Itch Management.
Topics: Acupuncture Therapy; Amines; Anesthetics, Local; Anticonvulsants; Antipruritics; Botulinum Toxins, T | 2016 |
2 trials available for doxepin and Peripheral Nerve Diseases
| Article | Year |
|---|---|
Topical application of doxepin hydrochloride, capsaicin and a combination of both produces analgesia in chronic human neuropathic pain: a randomized, double-blind, placebo-controlled study.
Topics: Administration, Topical; Adult; Antidepressive Agents, Tricyclic; Capsaicin; Chronic Disease; Double | 2000 |
[Doxepin in pain caused by peripheral neuropathy].
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Double-Blind Method; Doxepin; Drug Evaluation; Female; H | 1987 |
1 other study available for doxepin and Peripheral Nerve Diseases
| Article | Year |
|---|---|
Severe medication-induced peripheral neuropathy treated with topical doxepin cream in a paediatric patient with leukaemia.
Topics: Administration, Topical; Adolescent; Dosage Forms; Doxepin; Female; Humans; Mucormycosis; Peripheral | 2017 |