doxepin has been researched along with Peptic Ulcer in 6 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Peptic Ulcer: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Doxepin hydrochloride was given to 12 patients with duodenal ulcer and one patient with an anastomotic ulcer." | 3.66 | Tricyclic antidepressants in the treatment of peptic ulcer disease. ( Mangla, JC; Pereira, M, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Richelson, E | 1 |
| Mangla, JC | 1 |
| Pereira, M | 1 |
| Haggerty, JJ | 1 |
| Drossman, DA | 1 |
| Nanivadekar, A | 1 |
| Cunha, UV | 1 |
| Tripathi, BM | 1 |
| Misra, NP | 1 |
| Rao, S | 1 |
2 reviews available for doxepin and Peptic Ulcer
| Article | Year |
|---|---|
The use of tricyclic antidepressants in chronic gastrointestinal pain.
Topics: Abdomen; Antidepressive Agents, Tricyclic; Chronic Disease; Cimetidine; Doxepin; Humans; Pain; Pepti | 1982 |
Use of psychotropic drugs in patients with peptic ulcer.
Topics: Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Cimetidine; Doxepin; Drug Interact | 1985 |
4 other studies available for doxepin and Peptic Ulcer
| Article | Year |
|---|---|
Tricyclic antidepressants in the treatment of peptic ulcer disease.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Cimetidine; Doxepin; Duodenal Ulcer; Female; Histamin | 1982 |
Antidepressants in peptic ulcer.
Topics: Dibenzazepines; Doxepin; Humans; Peptic Ulcer; Trimipramine | 1986 |
Antidepressants: their uses in nonpsychiatric disorders of aging.
Topics: Affective Symptoms; Aged; Antidepressive Agents; Chronic Disease; Colonic Diseases, Functional; Depr | 1986 |
Clinical status of tricyclic antidepressants in peptic ulcer.
Topics: Adult; Dibenzazepines; Doxepin; Female; Humans; Male; Middle Aged; Peptic Ulcer; Trimipramine | 1986 |