doxepin has been researched along with Opioid-Related Disorders in 5 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Opioid-Related Disorders: Disorders related to or resulting from abuse or misuse of OPIOIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A high proportion of affective disorders has been found among opioid-dependent patients; these are responsive to psychotherapy and to antidepressant treatment with doxepin." | 3.67 | Psychiatric disorders in opioid-dependent patients. ( McLellan, AT; O'Brien, CP; Woody, GE, 1984) |
| "Doxepin was superior to placebo on Clinical Global Impressions and several factors of the Hamilton Rating Scale for Depression and the Profile of Mood States." | 2.65 | Doxepin as adjunctive therapy for depressed methadone maintenance patients: a double-blind study. ( Barranco, M; Kyle, EM; Seco, G; Titievsky, J, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dickmann, JR | 1 |
| Eversheim, F | 1 |
| McCaul, ME | 1 |
| Stitzer, ML | 1 |
| Bigelow, GE | 1 |
| Liebson, IA | 1 |
| O'Brien, CP | 2 |
| Woody, GE | 2 |
| McLellan, AT | 2 |
| Marcovici, M | 1 |
| Evans, BD | 1 |
| Titievsky, J | 1 |
| Seco, G | 1 |
| Barranco, M | 1 |
| Kyle, EM | 1 |
1 trial available for doxepin and Opioid-Related Disorders
| Article | Year |
|---|---|
Doxepin as adjunctive therapy for depressed methadone maintenance patients: a double-blind study.
Topics: Adult; Depressive Disorder; Double-Blind Method; Doxepin; Drug Therapy, Combination; Female; Humans; | 1982 |
4 other studies available for doxepin and Opioid-Related Disorders
| Article | Year |
|---|---|
Steroid responsive psychotic depression.
Topics: Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Ataxia; Benzodiaze | 2009 |
Outpatient methadone detoxification: effects of diazepam and doxepin as adjunct medications.
Topics: Adult; Diazepam; Doxepin; Humans; Methadone; Narcotics; Opioid-Related Disorders | 1984 |
Psychiatric disorders in opioid-dependent patients.
Topics: Counseling; Doxepin; Humans; Interview, Psychological; Mental Disorders; Mood Disorders; Opioid-Rela | 1984 |
The use of antidepressants with methadone in depressed maintenance patients.
Topics: Depressive Disorder; Doxepin; Female; Humans; Imipramine; Male; Methadone; Middle Aged; Opioid-Relat | 1982 |