doxepin has been researched along with Neurodermatitis in 2 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Neurodermatitis: An extremely variable eczematous skin disease that is presumed to be a response to prolonged vigorous scratching, rubbing, or pinching to relieve intense pruritus. It varies in intensity, severity, course, and morphologic expression in different individuals. Neurodermatitis is believed by some to be psychogenic. The circumscribed or localized form is often referred to as lichen simplex chronicus.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To expand on our previous findings in atopic dermatitis, the present multicenter double-blind trial was conducted to evaluate the safety and antipruritic efficacy of 5% doxepin hydrochloride cream in patients with lichen simplex chronicus (n = 136), nummular eczema (n = 87), or contact dermatitis (n = 86)." | 9.08 | The antipruritic effect of 5% doxepin cream in patients with eczematous dermatitis. Doxepin Study Group. ( Drake, LA; Millikan, LE, 1995) |
| " To expand on our previous findings in atopic dermatitis, the present multicenter double-blind trial was conducted to evaluate the safety and antipruritic efficacy of 5% doxepin hydrochloride cream in patients with lichen simplex chronicus (n = 136), nummular eczema (n = 87), or contact dermatitis (n = 86)." | 5.08 | The antipruritic effect of 5% doxepin cream in patients with eczematous dermatitis. Doxepin Study Group. ( Drake, LA; Millikan, LE, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Drake, LA | 1 |
| Millikan, LE | 1 |
| Thomson, KF | 1 |
| Highet, AS | 1 |
1 trial available for doxepin and Neurodermatitis
| Article | Year |
|---|---|
The antipruritic effect of 5% doxepin cream in patients with eczematous dermatitis. Doxepin Study Group.
Topics: Administration, Cutaneous; Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Antipruritics; Chi | 1995 |
1 other study available for doxepin and Neurodermatitis
| Article | Year |
|---|---|
5% doxepin cream to treat persistent lichenification in a child.
Topics: Doxepin; Histamine Antagonists; Humans; Infant; Male; Neurodermatitis; Recurrence; Treatment Outcome | 2001 |