doxepin has been researched along with Neoplasms in 5 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This research expands on our prior study, in which we assessed pain reduction after topical doxepin rinse in patients with oral mucositis resulting from cancer and cancer therapy." | 7.73 | Oral doxepin rinse: the analgesic effect and duration of pain reduction in patients with oral mucositis due to cancer therapy. ( Epstein, JB; Epstein, JD; Epstein, MS; Oien, H; Truelove, EL, 2006) |
| "To provide an effective continuum of the relief of severe carcinomatous pain with minimal side reactions, we initiated treatment with piroxicam (60 to 120 mg per day) and doxepin hydrochloride (25 to 225 mg per day)." | 7.67 | Piroxicam and doxepin--an alternative to narcotic analgesics in managing advanced cancer pain. ( Bier, R; Cohn, M; Cohn, ML; Machado, AF, 1988) |
| " In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
| "This research expands on our prior study, in which we assessed pain reduction after topical doxepin rinse in patients with oral mucositis resulting from cancer and cancer therapy." | 3.73 | Oral doxepin rinse: the analgesic effect and duration of pain reduction in patients with oral mucositis due to cancer therapy. ( Epstein, JB; Epstein, JD; Epstein, MS; Oien, H; Truelove, EL, 2006) |
| "To provide an effective continuum of the relief of severe carcinomatous pain with minimal side reactions, we initiated treatment with piroxicam (60 to 120 mg per day) and doxepin hydrochloride (25 to 225 mg per day)." | 3.67 | Piroxicam and doxepin--an alternative to narcotic analgesics in managing advanced cancer pain. ( Bier, R; Cohn, M; Cohn, ML; Machado, AF, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tukey, RH | 1 |
| Strassburg, CP | 1 |
| Kastrinsky, DB | 1 |
| Sangodkar, J | 1 |
| Zaware, N | 1 |
| Izadmehr, S | 1 |
| Dhawan, NS | 1 |
| Narla, G | 1 |
| Ohlmeyer, M | 1 |
| Epstein, JB | 1 |
| Epstein, JD | 1 |
| Epstein, MS | 1 |
| Oien, H | 1 |
| Truelove, EL | 1 |
| Storey, P | 1 |
| Trumble, M | 1 |
| Cohn, ML | 1 |
| Machado, AF | 1 |
| Bier, R | 1 |
| Cohn, M | 1 |
1 review available for doxepin and Neoplasms
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
4 other studies available for doxepin and Neoplasms
| Article | Year |
|---|---|
Reengineered tricyclic anti-cancer agents.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Dibenzazepines; Heterocyclic Compou | 2015 |
Oral doxepin rinse: the analgesic effect and duration of pain reduction in patients with oral mucositis due to cancer therapy.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Doxepin; Female; Humans; Male; Mid | 2006 |
Rectal doxepin and carbamazepine therapy in patients with cancer.
Topics: Administration, Rectal; Carbamazepine; Doxepin; Humans; Neoplasms | 1992 |
Piroxicam and doxepin--an alternative to narcotic analgesics in managing advanced cancer pain.
Topics: Adult; Aged; Aged, 80 and over; Doxepin; Drug Therapy, Combination; Female; Humans; Male; Middle Age | 1988 |