doxepin has been researched along with Myocardial Infarction in 1 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Maprotiline was associated with decreased PVCs in patients with a "high" baseline rate, while doxepin was associated with increased PVCs in this group." | 2.65 | Comparative cardiac effects of maprotiline and doxepin in elderly depressed patients. ( Ahles, S; Gwirtsman, H; Halaris, A; Hill, MA; Schwarcz, G; Shah, P, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahles, S | 1 |
| Gwirtsman, H | 1 |
| Halaris, A | 1 |
| Shah, P | 1 |
| Schwarcz, G | 1 |
| Hill, MA | 1 |
1 trial available for doxepin and Myocardial Infarction
| Article | Year |
|---|---|
Comparative cardiac effects of maprotiline and doxepin in elderly depressed patients.
Topics: Aged; Angina Pectoris; Anthracenes; Blood Pressure; Cardiac Complexes, Premature; Clinical Trials as | 1984 |