doxepin has been researched along with Kidney Failure, Chronic in 1 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We suggest that doxepin, a tricyclic antidepressant with anti-H1 receptor effect, can help improve pruritus resistant to antihistamines in end-stage renal disease patients who undergo hemodialysis." | 9.12 | Low-dose doxepin for treatment of pruritus in patients on hemodialysis. ( Farrokhi, F; Firouzan, A; Nasli Esfahani, E; Nasrollahi, A; Pour-Reza-Gholi, F, 2007) |
| "We suggest that doxepin, a tricyclic antidepressant with anti-H1 receptor effect, can help improve pruritus resistant to antihistamines in end-stage renal disease patients who undergo hemodialysis." | 5.12 | Low-dose doxepin for treatment of pruritus in patients on hemodialysis. ( Farrokhi, F; Firouzan, A; Nasli Esfahani, E; Nasrollahi, A; Pour-Reza-Gholi, F, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pour-Reza-Gholi, F | 1 |
| Nasrollahi, A | 1 |
| Firouzan, A | 1 |
| Nasli Esfahani, E | 1 |
| Farrokhi, F | 1 |
1 trial available for doxepin and Kidney Failure, Chronic
| Article | Year |
|---|---|
Low-dose doxepin for treatment of pruritus in patients on hemodialysis.
Topics: Adult; Aged; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Doxepin; Fem | 2007 |