doxepin has been researched along with Innate Inflammatory Response in 1 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We found the treatment of C6-glioma cells with LPS results in deleterious effects, including the augmentation of inflammatory cytokine levels (tumor necrosis factor-α, interleukin-1β), and suppresses the Akt phosphorylation." | 5.56 | Anti-inflammatory effects of doxepin hydrochloride against LPS-induced C6-glioma cell inflammatory reaction by PI3K-mediated Akt signaling. ( Bo, J; Duan, L; Tao, F; Wu, J; Yao, K; Zhang, J; Zhu, J; Zu, H, 2020) |
| "We found the treatment of C6-glioma cells with LPS results in deleterious effects, including the augmentation of inflammatory cytokine levels (tumor necrosis factor-α, interleukin-1β), and suppresses the Akt phosphorylation." | 1.56 | Anti-inflammatory effects of doxepin hydrochloride against LPS-induced C6-glioma cell inflammatory reaction by PI3K-mediated Akt signaling. ( Bo, J; Duan, L; Tao, F; Wu, J; Yao, K; Zhang, J; Zhu, J; Zu, H, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tao, F | 1 |
| Zhu, J | 1 |
| Duan, L | 1 |
| Wu, J | 1 |
| Zhang, J | 1 |
| Yao, K | 1 |
| Bo, J | 1 |
| Zu, H | 1 |
1 other study available for doxepin and Innate Inflammatory Response
| Article | Year |
|---|---|
Anti-inflammatory effects of doxepin hydrochloride against LPS-induced C6-glioma cell inflammatory reaction by PI3K-mediated Akt signaling.
Topics: Animals; Anti-Inflammatory Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Doxepin; Glioma | 2020 |