doxepin has been researched along with Eczema, Atopic in 11 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The current study was undertaken to compare the efficacy and safety of topical 5% doxepin cream in relieving pruritus associated with atopic dermatitis." | 9.07 | Relief of pruritus in patients with atopic dermatitis after treatment with topical doxepin cream. The Doxepin Study Group. ( Drake, LA; Fallon, JD; Sober, A, 1994) |
| " Since efficient benefit on pruritus and excoriations has been demonstrated with tricyclic agents, we investigated how the topical treatment with doxepin (5%, Boehringer Standard, Mannheim, Germany), a tricyclic compound with anticholinergic properties, may influence ACH induced itch and cutaneous sensations (erythema, wheal, axonreflex flare)." | 5.09 | Doxepin affects acetylcholine induced cutaneous reactions in atopic eczema. ( Groene, D; Heyer, G; Martus, P, 2001) |
| "The current study was undertaken to compare the efficacy and safety of topical 5% doxepin cream in relieving pruritus associated with atopic dermatitis." | 5.07 | Relief of pruritus in patients with atopic dermatitis after treatment with topical doxepin cream. The Doxepin Study Group. ( Drake, LA; Fallon, JD; Sober, A, 1994) |
| "We evaluated the pharmacokinetic profile of doxepin and desmethyldoxepin after topical application of doxepin hydrochloride 5% cream alone or in combination with 0." | 2.69 | Pharmacokinetics of doxepin in subjects with pruritic atopic dermatitis. ( Cohen, L; Drake, LA; Flood, JG; Gillies, R; Phillips, SB; Riordan, AT; Stiller, MJ, 1999) |
| " Marked sedation occurred in three of the first 10 subjects treated with topical doxepin, necessitating a reduction in dosage for the remaining six subjects." | 2.68 | The effects of topical doxepin on responses to histamine, substance P and prostaglandin E2 in human skin. ( Archer, CB; Kennedy, CT; Sabroe, RA, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Hoyos, CL | 1 |
| Peñuelas Leal, R | 1 |
| Echevarría, AG | 1 |
| Esquembre, AC | 1 |
| Spröhnle, JL | 1 |
| Magdaleno Tapial, J | 1 |
| Zaragoza Ninet, V | 1 |
| Danarti, R | 1 |
| Waskito, F | 1 |
| Indrastuti, N | 1 |
| Kelsay, K | 1 |
| Drake, LA | 3 |
| Fallon, JD | 1 |
| Sober, A | 1 |
| Shelley, WB | 1 |
| Shelley, ED | 1 |
| Talanin, NY | 1 |
| Sabroe, RA | 1 |
| Kennedy, CT | 1 |
| Archer, CB | 1 |
| Berberian, BJ | 1 |
| Breneman, DL | 1 |
| Gratton, D | 1 |
| Raimir, SS | 1 |
| Phillips, S | 1 |
| Sulica, VI | 1 |
| Bernstein, JE | 1 |
| Cohen, L | 1 |
| Gillies, R | 1 |
| Flood, JG | 1 |
| Riordan, AT | 1 |
| Phillips, SB | 1 |
| Stiller, MJ | 1 |
| Groene, D | 1 |
| Martus, P | 1 |
| Heyer, G | 1 |
| Harris, BA | 1 |
| Sherertz, EF | 1 |
| Flowers, FP | 1 |
2 reviews available for doxepin and Eczema, Atopic
| Article | Year |
|---|---|
Management of sleep disturbance associated with atopic dermatitis.
Topics: Algorithms; Clonidine; Dermatitis, Atopic; Doxepin; Histamine H1 Antagonists; Humans; Hypnotics and | 2006 |
Doxepin cream for eczema?
Topics: Administration, Topical; Adult; Antipruritics; Child; Dermatitis, Atopic; Doxepin; Humans | 2000 |
6 trials available for doxepin and Eczema, Atopic
| Article | Year |
|---|---|
Onset and duration of action of topical antihistamine: a study of histamine skin test response.
Topics: Administration, Topical; Adolescent; Adult; Allergens; Cross-Over Studies; Dermatitis, Atopic; Doubl | 2008 |
Relief of pruritus in patients with atopic dermatitis after treatment with topical doxepin cream. The Doxepin Study Group.
Topics: Administration, Cutaneous; Adult; Dermatitis, Atopic; Double-Blind Method; Doxepin; Eczema; Female; | 1994 |
The effects of topical doxepin on responses to histamine, substance P and prostaglandin E2 in human skin.
Topics: Administration, Topical; Adult; Antipruritics; Dermatitis, Atopic; Dinoprostone; Double-Blind Method | 1997 |
The addition of topical doxepin to corticosteroid therapy: an improved treatment regimen for atopic dermatitis.
Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Adult; Antipruritics; Dermatitis, Atopic; Double | 1999 |
Pharmacokinetics of doxepin in subjects with pruritic atopic dermatitis.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Antipruritics; Dermatitis, Atopic; Double- | 1999 |
Doxepin affects acetylcholine induced cutaneous reactions in atopic eczema.
Topics: Acetylcholine; Administration, Cutaneous; Adult; Antipruritics; Area Under Curve; Cholinergic Antago | 2001 |
3 other studies available for doxepin and Eczema, Atopic
| Article | Year |
|---|---|
Systemic allergic dermatitis from doxepin: A case report.
Topics: Dermatitis, Allergic Contact; Dermatitis, Atopic; Doxepin; Eczema; Humans | 2023 |
Self-potentiating allergic contact dermatitis caused by doxepin hydrochloride cream.
Topics: Adult; Aged; Dermatitis, Allergic Contact; Dermatitis, Atopic; Dermatologic Agents; Doxepin; Drug Er | 1996 |
Improvement of chronic neurotic excoriations with oral doxepin therapy.
Topics: Administration, Oral; Aged; Chronic Disease; Depression; Dermatitis, Atopic; Doxepin; Female; Humans | 1987 |