doxepin has been researched along with Drug Overdose in 12 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Doxepin is a tricyclic antidepressant from the group of dibenzoxepines." | 5.38 | [Prolonged toxic coma and anisocoria secondary to doxepin, lorazepam and phenobarbital poisoning--case study]. ( Kołodziej, M; Krajewska, A; Majewska, M; Szponar, J, 2012) |
| " Retrospectively, both subjects suffered from psychiatric disorders and in case 2, the subject was treated for depression with doxepin." | 3.81 | Sleep self-intoxication and sleep driving as rare zolpidem-induced complex behaviour. ( Paulke, A; Toennes, SW; Wunder, C, 2015) |
| "Doxepin is a tricyclic antidepressant from the group of dibenzoxepines." | 1.38 | [Prolonged toxic coma and anisocoria secondary to doxepin, lorazepam and phenobarbital poisoning--case study]. ( Kołodziej, M; Krajewska, A; Majewska, M; Szponar, J, 2012) |
| "Amitriptyline was used as internal standard." | 1.37 | [Determination of doxepin in whole blood by SPE-LC-MS/MS]. ( Gong, FJ; Wu, ZP; Yan, SM; Zhang, RS, 2011) |
| "This is a case report of a CPP treated by a pain physician." | 1.35 | Alleged breaches of "standards of medical care" in a patient overdose death possibly related to chronic opioid analgesic therapy, application of the controlled substances model guidelines: case report. ( Cole, B; Fishbain, DA; Gao, J; Lewis, JE; Rosomoff, RS, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, XY | 1 |
| Song, XT | 1 |
| Zhang, Y | 1 |
| Perza, MN | 1 |
| Schneider, LA | 1 |
| Rosini, JM | 1 |
| Magdalan, J | 1 |
| Zawadzki, M | 1 |
| Słoka, T | 1 |
| Sozański, T | 1 |
| Paulke, A | 1 |
| Wunder, C | 1 |
| Toennes, SW | 1 |
| Fishbain, DA | 1 |
| Lewis, JE | 1 |
| Gao, J | 1 |
| Cole, B | 1 |
| Rosomoff, RS | 1 |
| Gong, FJ | 1 |
| Yan, SM | 1 |
| Wu, ZP | 1 |
| Zhang, RS | 1 |
| Kołodziej, M | 1 |
| Majewska, M | 1 |
| Krajewska, A | 1 |
| Szponar, J | 1 |
| Bateman, DN | 1 |
| Chick, J | 1 |
| Good, AM | 1 |
| Kelly, CA | 1 |
| Masterton, G | 1 |
| Sakka, SG | 1 |
| Kuethe, F | 1 |
| Demme, U | 1 |
| Hüttemann, E | 1 |
| Retterstøl, N | 1 |
| Harrigan, RA | 1 |
| Brady, WJ | 1 |
| Wrenn, K | 1 |
| Smith, BA | 1 |
| Slovis, CM | 1 |
1 review available for doxepin and Drug Overdose
| Article | Year |
|---|---|
Death due to overdose of antidepressants: experiences from Norway.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Doxepin; Drug Overdose; Female; Human | 1993 |
11 other studies available for doxepin and Drug Overdose
| Article | Year |
|---|---|
Wide QRS Complex Tachycardia With a Dominant R-Wave in Lead aVR-Is It Ventricular Tachycardia?
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Diagnosis, Differential; Doxepin; Drug Overdose; El | 2020 |
Suspected tricyclic antidepressant overdose successfully treated with lipids.
Topics: Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Doxepin; Drug Overdose; Fat Em | 2013 |
Suicidal overdose with relapsing clomipramine concentrations due to a large gastric pharmacobezoar.
Topics: Adult; Antidepressive Agents, Tricyclic; Bezoars; Clomipramine; Delayed-Action Preparations; Doxepin | 2013 |
Sleep self-intoxication and sleep driving as rare zolpidem-induced complex behaviour.
Topics: Adult; Amnesia; Antidepressive Agents, Tricyclic; Automobile Driving; Depression; Doxepin; Drug Over | 2015 |
Alleged breaches of "standards of medical care" in a patient overdose death possibly related to chronic opioid analgesic therapy, application of the controlled substances model guidelines: case report.
Topics: Adult; Analgesics, Opioid; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Diazepam; Doxepin; | 2009 |
[Determination of doxepin in whole blood by SPE-LC-MS/MS].
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biomarkers; Chromatography, Liquid; Doxepin; Drug O | 2011 |
[Prolonged toxic coma and anisocoria secondary to doxepin, lorazepam and phenobarbital poisoning--case study].
Topics: Antidepressive Agents, Tricyclic; Coma; Complex Mixtures; Doxepin; Drug Overdose; Drug Synergism; Hu | 2012 |
Are selective serotonin re-uptake inhibitors associated with an increased risk of self-harm by antidepressant overdose?
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Doxepin; Drug Ove | 2004 |
[Intoxication with a tricyclic antidepressant].
Topics: Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Doxepin; Drug Overdose; Female; Hemope | 2007 |
ECG abnormalities in tricyclic antidepressant ingestion.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; An | 1999 |
Profound alkalemia during treatment of tricyclic antidepressant overdose: a potential hazard of combined hyperventilation and intravenous bicarbonate.
Topics: Adult; Aged; Alkalosis; Antidepressive Agents, Tricyclic; Bicarbonates; Critical Care; Doxepin; Drug | 1992 |