doxepin has been researched along with Diffuse Myofascial Pain Syndrome in 2 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this review is to present relatively detailed information on the characteristics of tricyclic antidepressants, mainly amitriptyline hydrochloride and doxepin hydrochloride, for use as an integral part of the safe and effective management of fibromyalgia and, to a lesser extent, other chronic pain syndromes." | 4.79 | A guide to the understanding and use of tricyclic antidepressants in the overall management of fibromyalgia and other chronic pain syndromes. ( Godfrey, RG, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laske, C | 1 |
| Stransky, E | 1 |
| Eschweiler, GW | 1 |
| Klein, R | 1 |
| Wittorf, A | 1 |
| Leyhe, T | 1 |
| Richartz, E | 1 |
| Köhler, N | 1 |
| Bartels, M | 1 |
| Buchkremer, G | 1 |
| Schott, K | 1 |
| Godfrey, RG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Internet-Enhanced Management of Fibromyalgia[NCT00423631] | 118 participants (Actual) | Interventional | 2006-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for doxepin and Diffuse Myofascial Pain Syndrome
| Article | Year |
|---|---|
A guide to the understanding and use of tricyclic antidepressants in the overall management of fibromyalgia and other chronic pain syndromes.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chronic Disease; Doxepin; Fibromyalgia; Humans; Lif | 1996 |
1 other study available for doxepin and Diffuse Myofascial Pain Syndrome
| Article | Year |
|---|---|
Increased BDNF serum concentration in fibromyalgia with or without depression or antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Depressive Disorder, | 2007 |