doxepin has been researched along with Dermatitis, Eczematous in 7 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To expand on our previous findings in atopic dermatitis, the present multicenter double-blind trial was conducted to evaluate the safety and antipruritic efficacy of 5% doxepin hydrochloride cream in patients with lichen simplex chronicus (n = 136), nummular eczema (n = 87), or contact dermatitis (n = 86)." | 9.08 | The antipruritic effect of 5% doxepin cream in patients with eczematous dermatitis. Doxepin Study Group. ( Drake, LA; Millikan, LE, 1995) |
| "The current study was undertaken to compare the efficacy and safety of topical 5% doxepin cream in relieving pruritus associated with atopic dermatitis." | 9.07 | Relief of pruritus in patients with atopic dermatitis after treatment with topical doxepin cream. The Doxepin Study Group. ( Drake, LA; Fallon, JD; Sober, A, 1994) |
| " To expand on our previous findings in atopic dermatitis, the present multicenter double-blind trial was conducted to evaluate the safety and antipruritic efficacy of 5% doxepin hydrochloride cream in patients with lichen simplex chronicus (n = 136), nummular eczema (n = 87), or contact dermatitis (n = 86)." | 5.08 | The antipruritic effect of 5% doxepin cream in patients with eczematous dermatitis. Doxepin Study Group. ( Drake, LA; Millikan, LE, 1995) |
| "The current study was undertaken to compare the efficacy and safety of topical 5% doxepin cream in relieving pruritus associated with atopic dermatitis." | 5.07 | Relief of pruritus in patients with atopic dermatitis after treatment with topical doxepin cream. The Doxepin Study Group. ( Drake, LA; Fallon, JD; Sober, A, 1994) |
| " She had recently developed a generalized eczematous rash for which she was prescribed doxepin hydrochloride 5% cream." | 3.70 | Doxepin toxicity in a child following topical administration. ( Negrusz, A; Spiegel, K; Toerne, TS; Zell-Kanter, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Hoyos, CL | 1 |
| Peñuelas Leal, R | 1 |
| Echevarría, AG | 1 |
| Esquembre, AC | 1 |
| Spröhnle, JL | 1 |
| Magdaleno Tapial, J | 1 |
| Zaragoza Ninet, V | 1 |
| Drake, LA | 2 |
| Millikan, LE | 1 |
| Vo, MY | 1 |
| Williamsen, AR | 1 |
| Wasserman, GS | 1 |
| Fallon, JD | 1 |
| Sober, A | 1 |
| Rapaport, MJ | 1 |
| Zell-Kanter, M | 1 |
| Toerne, TS | 1 |
| Spiegel, K | 1 |
| Negrusz, A | 1 |
2 trials available for doxepin and Dermatitis, Eczematous
| Article | Year |
|---|---|
The antipruritic effect of 5% doxepin cream in patients with eczematous dermatitis. Doxepin Study Group.
Topics: Administration, Cutaneous; Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Antipruritics; Chi | 1995 |
Relief of pruritus in patients with atopic dermatitis after treatment with topical doxepin cream. The Doxepin Study Group.
Topics: Administration, Cutaneous; Adult; Dermatitis, Atopic; Double-Blind Method; Doxepin; Eczema; Female; | 1994 |
5 other studies available for doxepin and Dermatitis, Eczematous
| Article | Year |
|---|---|
Systemic allergic dermatitis from doxepin: A case report.
Topics: Dermatitis, Allergic Contact; Dermatitis, Atopic; Doxepin; Eczema; Humans | 2023 |
Toxic reaction from topically applied doxepin in a child with eczema.
Topics: Administration, Cutaneous; Adrenergic Uptake Inhibitors; Antipruritics; Child, Preschool; Doxepin; E | 1995 |
Doxepin cream for pruritus.
Topics: Administration, Cutaneous; Controlled Clinical Trials as Topic; Doxepin; Eczema; Histamine H1 Antago | 1994 |
Allergic contact dermatitis from doxepin cream.
Topics: Administration, Cutaneous; Antipruritics; Dermatitis, Allergic Contact; Doxepin; Eczema; Humans; Oin | 1996 |
Doxepin toxicity in a child following topical administration.
Topics: Administration, Topical; Antipruritics; Child, Preschool; Doxepin; Eczema; Female; Humans; Sleep Sta | 2000 |