Page last updated: 2024-10-26

doxepin and Depressive Disorder

doxepin has been researched along with Depressive Disorder in 124 studies

Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.

Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.

Research Excerpts

ExcerptRelevanceReference
" Forty patients with major depressive disorder (according to DSM-III-R criteria) were enrolled in a 6-week double-blind parallel group study of fluoxetine (N = 20) or doxepin (N = 20)."9.08Electrocardiographic effects of fluoxetine and doxepin in patients with major depressive disorder. ( Baker, B; Dorian, P; Irvine, MJ; Mitchell, J; Sandor, P; Schell, C; Shapiro, C, 1997)
"Sixty patients with chronic pain of the low back or cervical spine concomitant with clinical depression were studied in a 6-week, randomized, double-blind comparison of doxepin and placebo."9.05Doxepin's effects on chronic pain and depression: a controlled study. ( Cork, RC; Crago, BR; Davis, TP; Hameroff, SR; Lerman, JC; Neuman, CP; Watts, KS; Weiss, JL; Womble, JR, 1984)
"Doxepin and desipramine at final doses of 188 and 173 mg/day, respectively, were compared in 36 volunteers with major affective or dysthymic disorder and chronic back pain."9.05Antidepressants in concomitant chronic back pain and depression: doxepin and desipramine compared. ( Benedetti, C; Bokan, JA; Butler, S; Phillips, M; Spengler, D; Ward, N, 1984)
"A 46-year-old man suffering from neurotic depression complicated by alcohol and benzodiazepine dependence developed Coombs'-positive hemolytic anemia and thrombocytopenia with acute renal failure after 5 weeks of monotherapy with doxepin at a final dosage of 100 mg daily."7.67A case of immune complex hemolytic anemia, thrombocytopenia, and acute renal failure associated with doxepin use. ( Conradty, M; Grohmann, R; Londong, V; Rüther, E; Witzgall, H; Wolf, B, 1989)
"A group of patients with both depression and chronic pain were treated with doxepin for 4 weeks."7.66Urinary 3-methoxy-4-hydroxyphenethylene glycol in the prediction of pain and depression relief with doxepin: preliminary findings. ( Bloom, VL; Fawcett, J; Friedel, RO; Ward, NG, 1983)
"A 66-year-old woman had tinnitus while receiving a conventional dose of doxepin."7.66Doxepin and tinnitus. ( Evans, DL; Golden, RN; Nau, CH, 1983)
"A case is described of ventricular arrhythmias associated with doxepin and amitriptyline treatment in a patient with preexisting heart disease."7.66Ventricular arrhythmias induced by doxepin and amitriptyline: case report. ( Faber, R; Todd, RD, 1983)
"Average maximum daily dosage was 83 mg/d in the control and 95 mg/d in the intervention group (F=19."6.73A randomized controlled clinical trial comparing "guideline exposed" and "guideline naive" physicians in respect to dosage selection and treatment outcome with doxepin in depressive disorders. ( Linden, M; Schotte, K, 2007)
"Fluoxetine was compared to doxepin in geriatric out-patients with major depressive illness."6.66Double-blind comparative trials of fluoxetine and doxepin in geriatric patients with major depressive disorder. ( Cohn, JB; Feighner, JP, 1985)
" Forty patients with major depressive disorder (according to DSM-III-R criteria) were enrolled in a 6-week double-blind parallel group study of fluoxetine (N = 20) or doxepin (N = 20)."5.08Electrocardiographic effects of fluoxetine and doxepin in patients with major depressive disorder. ( Baker, B; Dorian, P; Irvine, MJ; Mitchell, J; Sandor, P; Schell, C; Shapiro, C, 1997)
"After controlled treatment with either imipramine or doxepin with additional psychotherapy, 30 patients with pure panic disorder and 20 with concomitant depression were followed under ordinary treatment conditions over a 5-year period."5.08Fluctuation of symptoms and social functioning in panic disorder with or without concomitant depression. A 5-year prospective follow-up. ( Albus, M; Scheibe, G; Scherer, J, 1995)
"50 patients with panic disorder (30 without and 20 with concomitant depression) were enrolled in a controlled treatment study using either imipramine or doxepin in addition to supportive psychotherapy and were then studied under naturalistic treatment conditions over a 5-year period."5.08Panic disorder with or without concomitant depression 5 years after treatment: a prospective follow-up. ( Albus, M; Scheibe, G; Scherer, J, 1995)
"Patients with chronic low-back pain and depression were treated double blind with desipramine or doxepin."5.06Tricyclic antidepressants for chronic low-back pain. Mechanisms of action and predictors of response. ( Ward, NG, 1986)
"The efficacy of low doses (10 to 20 mg daily) of doxepin in the treatment of depressive disorders in elderly inpatients was assessed by a double-blind study in 24 patients."5.06Effective low dose tricyclic antidepressant treatment for depressed geriatric rehabilitation patients. A double-blind study. ( Frengley, JD; Lakshmanan, M; Mion, LC, 1986)
"Sixty patients with chronic pain of the low back or cervical spine concomitant with clinical depression were studied in a 6-week, randomized, double-blind comparison of doxepin and placebo."5.05Doxepin's effects on chronic pain and depression: a controlled study. ( Cork, RC; Crago, BR; Davis, TP; Hameroff, SR; Lerman, JC; Neuman, CP; Watts, KS; Weiss, JL; Womble, JR, 1984)
"Doxepin and desipramine at final doses of 188 and 173 mg/day, respectively, were compared in 36 volunteers with major affective or dysthymic disorder and chronic back pain."5.05Antidepressants in concomitant chronic back pain and depression: doxepin and desipramine compared. ( Benedetti, C; Bokan, JA; Butler, S; Phillips, M; Spengler, D; Ward, N, 1984)
"To address this issue, the authors studied the cardiovascular effects of doxepin in 32 depressed patients with preexisting left ventricular impairment, ventricular arrhythmias, and/or conduction disease."3.68Is doxepin a safer tricyclic for the heart? ( Dalack, GW; Giardina, EG; Glassman, AH; Roose, SP; Walsh, BT; Woodring, S, 1991)
"A 46-year-old man suffering from neurotic depression complicated by alcohol and benzodiazepine dependence developed Coombs'-positive hemolytic anemia and thrombocytopenia with acute renal failure after 5 weeks of monotherapy with doxepin at a final dosage of 100 mg daily."3.67A case of immune complex hemolytic anemia, thrombocytopenia, and acute renal failure associated with doxepin use. ( Conradty, M; Grohmann, R; Londong, V; Rüther, E; Witzgall, H; Wolf, B, 1989)
"A 66-year-old woman had tinnitus while receiving a conventional dose of doxepin."3.66Doxepin and tinnitus. ( Evans, DL; Golden, RN; Nau, CH, 1983)
"A case is described of ventricular arrhythmias associated with doxepin and amitriptyline treatment in a patient with preexisting heart disease."3.66Ventricular arrhythmias induced by doxepin and amitriptyline: case report. ( Faber, R; Todd, RD, 1983)
"A group of patients with both depression and chronic pain were treated with doxepin for 4 weeks."3.66Urinary 3-methoxy-4-hydroxyphenethylene glycol in the prediction of pain and depression relief with doxepin: preliminary findings. ( Bloom, VL; Fawcett, J; Friedel, RO; Ward, NG, 1983)
"Average maximum daily dosage was 83 mg/d in the control and 95 mg/d in the intervention group (F=19."2.73A randomized controlled clinical trial comparing "guideline exposed" and "guideline naive" physicians in respect to dosage selection and treatment outcome with doxepin in depressive disorders. ( Linden, M; Schotte, K, 2007)
" Patients were treated with either amitriptyline (n = 69) or doxepin (n = 15); the mean dosage at endpoint was 126 +/- 35 mg and 155 +/- 47 mg, respectively."2.71Therapeutic drug monitoring of tricyclic antidepressants: how does it work under clinical conditions? ( Dragicevic, A; Fric, M; Gaertner, I; Grasmäder, K; Härtter, S; Hermann, E; Hiemke, C; Kuss, HJ; Laux, G; Müller, MJ; Oehl, W; Rao, ML; Rollmann, N; Weber-Labonte, M; Weigmann, H, 2003)
"In the treatment of depressive disorders the onset of action can be accelerated if the antidepressant drug is initially administered by intravenous infusion."2.68On the problems of switching from intravenous to oral administration in drug treatment of endogenous depression--a placebo-controlled double-blind trial with doxepin. ( Adler, L; Böke, J; Hajak, G; Hoffmann, G; Huether, G; Issinger, J; Kunert, HJ; Lehmann, K; Rüther, E, 1997)
"Placebo for 1 week, 2 weeks of titration with either drug in the dosage range of 75 mg/day up to a maximum of 200 mg/day."2.67A comparison of the cardiac safety and therapeutic efficacy of trimipramine versus doxepin in geriatric depressed patients. ( Amin, M; Dastoor, D; MacDonald, C; Mirmiran, J; Nair, NP; Phillips, R; Schwartz, G; Thavundayil, JX, 1993)
" Two groups of 22 patients each received amitriptylinoxide and doxepine respectively at a daily dosage of 120-360 mg for a period of 4 weeks."2.67A double-blind comparison of amitriptylinoxide versus doxepine in the treatment of severe depression. ( Diehl, B; Heinrich, T; König, W, 1994)
"Paroxetine is an antidepressant that acts through selective inhibition of serotonin reuptake."2.67Two combined, multicenter double-blind studies of paroxetine and doxepin in geriatric patients with major depression. ( Cohn, CK; Cohn, JB; Dunner, DL; Feighner, JP; Fieve, RR; Halikas, JP; Hartford, JT; Hearst, ED; Settle, EC; Walshe, T, 1992)
"The increased orthostatic hypotension occurred early in treatment and at low doses of imipramine."2.66Orthostatic effect of imipramine and doxepin in depressed geriatric outpatients. ( Aldrich, J; Conolly, ME; Gerner, R; Hill, M; Jarvik, LF; Joseph, J; Linde, S; Mintz, J; Neshkes, RE; Rosen, R, 1985)
"After a 1-week placebo washout, 25 depressed hospitalized patients were treated for 4 weeks with trimipramine or doxepin in a fixed equivalent dosage schedule ending in 150 mg h."2.66A comparative trial of the antidepressant, anxiolytic, and cardiovascular effects of trimipramine and doxepin in depressed hospitalized patients. ( Assalian, P; Phillips, R; Rosengarten, MD, 1985)
"Fluoxetine was compared to doxepin in geriatric out-patients with major depressive illness."2.66Double-blind comparative trials of fluoxetine and doxepin in geriatric patients with major depressive disorder. ( Cohn, JB; Feighner, JP, 1985)
"Doxepin was superior to placebo on Clinical Global Impressions and several factors of the Hamilton Rating Scale for Depression and the Profile of Mood States."2.65Doxepin as adjunctive therapy for depressed methadone maintenance patients: a double-blind study. ( Barranco, M; Kyle, EM; Seco, G; Titievsky, J, 1982)
"Clomipramine was effective, safe, and well tolerated as compared to doxepin in the treatment of outpatients with neurotic depression."2.65A comparison of clomipramine and doxepin in neurotic depression. ( Horwitz, IM; Kornhaber, A, 1984)
"Maprotiline was associated with decreased PVCs in patients with a "high" baseline rate, while doxepin was associated with increased PVCs in this group."2.65Comparative cardiac effects of maprotiline and doxepin in elderly depressed patients. ( Ahles, S; Gwirtsman, H; Halaris, A; Hill, MA; Schwarcz, G; Shah, P, 1984)
" A significant positive correlation was obtained between dosage and blood levels of maprotiline and doxepin, but there was no correlation between blood levels and clinical response."2.65Therapeutic superiority of maprotiline versus doxepin in geriatric depression. ( Ahles, S; DeMet, E; Gwirtsman, HE; Halaris, A; Hill, MA, 1983)
"Treatment with imipramine and doxepin, but not placebo, was associated with significant improvement (P less than 0."2.65Cardiovascular effects of tricyclic antidepressants in depressed patients with chronic heart disease. ( Barnes, RF; Caldwell, JH; Gumbrecht, G; Raskind, MA; Ritchie, JL; Veith, RC, 1982)
" The plasma concentration of both doxepin and nordoxepin correlated significantly with the oral dosage of doxepin (doxepin: r = +0."1.37Doxepin concentrations in plasma and cerebrospinal fluid. ( Fassbender, K; Maurer, HH; Remane, D; Schomburg, R; Spiegel, J, 2011)
"Doctors' prescription and dosing behaviour was investigated using data from 9 clinical trials in 550 patients treated with psychotropics."1.29Correct titration of non-drugs and some other methodological issues. ( Beneke, M; Fritze, J; Rasmus, W; Rød, IS, 1994)
"Doxepin has gained favour for use in the geriatric population due to claims of low cardiovascular side effects."1.28Comparative plasma levels of doxepin and desipramine in the elderly. ( Ancill, RJ; Gosselin, C, 1989)
" Mean DMD t1/2 was not significantly affected by multiple dosing (34."1.27Multiple-dose doxepin kinetics in depressed patients. ( Fann, WE; Faulkner, RD; Lee, CS; Lewis, WA; Pitts, WM, 1983)
" Regardless of the reason for use, nonpsychiatric physicians were found to use relatively low dosages, rarely plan or effect dosage increases, and rarely discontinue medication."1.27Antidepressant treatment of medical-surgical inpatients by nonpsychiatric physicians. ( Callies, AL; Popkin, MK, 1987)
"Cerebrotendinous xanthomatosis is a genetically transmitted disease that is associated with deposition of cholestanol in the central nervous system and Achilles tendons."1.27Depression in a patient with dementia secondary to cerebrotendinous xanthomatosis. ( Shapiro, S, 1983)
"Desipramine was associated with a much higher frequency of jitteriness than was imipramine."1.27The jitteriness syndrome in panic disorder patients treated with antidepressants. ( Balon, R; Lycaki, H; Pohl, R; Yeragani, VK, 1988)

Research

Studies (124)

TimeframeStudies, this research(%)All Research%
pre-199079 (63.71)18.7374
1990's34 (27.42)18.2507
2000's8 (6.45)29.6817
2010's2 (1.61)24.3611
2020's1 (0.81)2.80

Authors

AuthorsStudies
Hashmi, HZ1
Kaur, J1
Stout, SC1
Drake, T1
Sun, Y1
Liang, Y1
Jiao, Y1
Lin, J1
Qu, H1
Xu, J1
Zhao, C1
Schomburg, R1
Remane, D1
Fassbender, K1
Maurer, HH1
Spiegel, J1
Müller, MJ1
Dragicevic, A1
Fric, M1
Gaertner, I1
Grasmäder, K1
Härtter, S2
Hermann, E1
Kuss, HJ1
Laux, G3
Oehl, W1
Rao, ML2
Rollmann, N1
Weigmann, H1
Weber-Labonte, M1
Hiemke, C2
Labbate, LA1
Croft, HA1
Oleshansky, MA1
Bajbouj, M1
Gallinat, J1
Lang, UE1
Hellen, F1
Vesper, J1
Lisanby, SH1
Danker-Hopfe, H1
Neu, P1
Linden, M1
Schotte, K1
Kiev, A1
Feighner, JP4
Ansseau, M1
Ansoms, C1
Beckers, G1
Bogaerts, M1
Botte, L1
De Buck, R1
Diricq, S1
Dumortier, A1
Jansegers, E1
Owieczka, J1
Ward, NG3
Bloom, VL2
Dworkin, S1
Fawcett, J2
Narasimhachari, N1
Friedel, RO3
Ahles, S2
Gwirtsman, H1
Halaris, A2
Shah, P1
Schwarcz, G1
Hill, MA2
Hameroff, SR1
Weiss, JL1
Lerman, JC1
Cork, RC1
Watts, KS1
Crago, BR1
Neuman, CP1
Womble, JR1
Davis, TP1
Ward, N1
Bokan, JA1
Phillips, M1
Benedetti, C1
Butler, S1
Spengler, D1
Luchins, DJ1
Jarvik, LF3
Read, SL1
Mintz, J3
Neshkes, RE2
Gwirtsman, HE1
DeMet, E1
Ayd, FJ2
Kornhaber, A1
Horwitz, IM1
de Montigny, C1
Cournoyer, G1
Morissette, R1
Langlois, R1
Caillé, G1
Schwab, JJ1
Golden, RN1
Evans, DL1
Nau, CH1
Faulkner, RD1
Pitts, WM1
Lee, CS1
Lewis, WA1
Fann, WE1
Todd, RD1
Faber, R1
Freinhar, J1
Rickels, K4
Csanalosi, I1
Werblowsky, J1
Weise, CC2
Weinstock, R1
Brown, AS1
Winokur, A1
Von Poelnitz, M1
Asnis, GM1
Halbreich, U1
Nathan, RS1
Ostrow, L1
Novacenko, H1
Endicott, J1
Sachar, EJ1
Khan, MC1
Bennie, EH1
Stulemeijer, SM1
Ravens, MA1
Pishkin, V1
Shurley, JT1
Veith, RC2
Raskind, MA2
Barnes, RF2
Gumbrecht, G2
Ritchie, JL2
Halter, JB1
Dilsaver, SC2
Domino, L1
Hekimian, LJ1
Friedhoff, AJ1
Brunswick, DJ1
Amsterdam, JD2
Potter, L2
Caroff, S2
Shapiro, S1
Friedman, J1
McCallum, P1
Meares, R1
Woody, GE1
O'Brien, CP1
McLellan, AT1
Marcovici, M1
Evans, BD1
McEvoy, JP2
Sheridan, WF1
Stewart, WR1
Ban, TA2
Wilson, WH2
Guy, W2
Schaffer, JD2
Caldwell, JH1
Brunswick, D1
Conn, JW1
Petrie, WM1
Aronoff, GM1
Evans, WO1
Nasrallah, HA1
Lyskowksi, J1
Schroeder, D1
Roth, T1
Zorick, F1
Wittig, R1
McLenaghan, A1
Roehrs, T1
Steuer, J1
Gerner, R2
Titievsky, J1
Seco, G1
Barranco, M1
Kyle, EM1
Linnoila, M2
Jobson, KO1
Gilliam, JH1
Paine, RL1
Finnerty, RJ1
Goldberg, HL1
Seppala, T1
Mattila, MJ1
Vihko, R1
Pakarinen, A1
Skinner, T1
Lingjaerde, O1
Jørgensen, J1
Støren, R1
Thomle, S1
Wendt Raeder, L1
Ruud, LE1
Schetelig, E1
Sveaas, HK1
Leivestad, O1
Albus, M3
Scheibe, G3
Scherer, J2
Nair, NP1
Amin, M1
Schwartz, G1
Dastoor, D1
Thavundayil, JX1
Mirmiran, J1
MacDonald, C1
Phillips, R3
Rechlin, T1
Beneke, M1
Rasmus, W1
Rød, IS1
Fritze, J1
Ferguson, JM1
Mendels, J1
Manowitz, NR1
König, W2
Heinrich, T1
Diehl, B1
Curran, S1
Cheung, P1
Philipp, M3
Kohnen, R1
Benkert, O1
Deister, A1
Staberock, U1
Höflich, G1
Möller, HJ1
Marttila, M1
Jääskeläinen, J1
Järvi, R1
Romanov, M1
Miettinen, E1
Sorri, P1
Ahlfors, U1
Zivkov, M1
Baker, B3
Dorian, P3
Sandor, P3
Shapiro, C2
Schell, C1
Mitchell, J1
Irvine, MJ1
Hrdina, PD4
Bakish, D4
Ravindran, A1
Chudzik, J1
Cavazzoni, P1
Lapierre, YD4
Adler, L1
Hajak, G1
Lehmann, K1
Kunert, HJ1
Hoffmann, G1
Issinger, J1
Böke, J1
Huether, G1
Rüther, E2
Deuschle, M2
Schmider, J1
Weber, B1
Standhardt, H2
Körner, A1
Lammers, CH1
Schweiger, U1
Hartmann, A1
Heuser, I2
Khaykin, Y1
Mironov, D1
Irvine, J2
Newman, D1
McKessok, D1
Mendlowitz, S1
Nuijten, MJ1
Hardens, M1
Souêtre, E1
Slomski, AJ1
Koskentausta, T1
Sobanski, E1
Schmidt, MH1
Gorelick, DA1
Leucht, S1
Steimer, W1
Kreuz, S1
Abraham, D1
Orsulak, PJ1
Kissling, W1
Barańczyk-Kuźma, A1
Sawicki, J1
Kuźma, M1
Jagiełło, J1
Dunner, DL1
Cohn, JB2
Walshe, T1
Cohn, CK1
Fieve, RR1
Halikas, JP1
Hartford, JT1
Hearst, ED1
Settle, EC1
Shafey, H1
Leinonen, E1
Lillsunde, P1
Laukkanen, V1
Ylitalo, P1
Roose, SP2
Dalack, GW2
Glassman, AH2
Woodring, S1
Walsh, BT1
Giardina, EG1
Swenson, S2
Deptula, D1
Pomara, N1
Lazarus, A1
Meador-Woodruff, JH1
Majchrzak, MJ1
Lesch, KP1
Stein, A1
Gosselin, C1
Ancill, RJ1
Sachdev, PS1
Small, GW1
Assalian, P2
Rosengarten, MD2
Churchill, CM1
Pariser, SF1
Larson, CN1
Tamminen, TT1
Lehtinen, VV1
Smith, WT1
Wolf, B1
Conradty, M1
Grohmann, R1
Witzgall, H1
Londong, V1
Feighner, J1
Hendrickson, G1
Miller, L1
Stern, W1
el-Yazigi, A1
Chaleby, K1
Horn, E1
Browne, M1
Maier, W2
Pohl, R1
Yeragani, VK1
Balon, R1
Lycaki, H1
Marshall, ZT1
Lippmann, SB1
Lee, HK1
Geeze, DS1
Wise, MG1
Stigelman, WH1
Tollison, CD1
Kriegel, ML1
Lieff, S1
Herrmann, N1
Light, RW1
Merrill, EJ1
Despars, J1
Gordon, GH1
Mutalipassi, LR1
Lodge, GJ1
Freeman, HL1
True, BL1
Perry, PJ1
Burns, EA1
Biedermann, HJ1
Lapeer, GL1
Mauri, M1
McGhie, A1
Lennhoff, M1
Lakshmanan, M1
Mion, LC1
Frengley, JD1
Callies, AL1
Popkin, MK1
Harris, SJ1
Parent, M1
Lyons, JS1
Rosen, AJ1
Dysken, MW1
Joseph, J1
Linde, S1
Aldrich, J1
Conolly, ME1
Rosen, R1
Hill, M1
Kemp, J1
Ilett, KF1
Booth, J1
Hackett, LP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study of Antidepressants in Parkinson's Disease[NCT00086190]Phase 3115 participants (Actual)Interventional2005-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Beck Depression Inventory II (BDI-II)

Beck Depression Inventory II ranges from 0-63. Higher score indicates more severe depression. 0-13 minimal depression, 14-19 mild depression, 20-28 moderate depression, 29-63 severe depression. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in BDI-II score (Mean)
Paroxetine-9.7
Venlafaxine Extended Release-9.6
Placebo-5.2

Change in Brief Psychiatric Rating Scale (BPRS)

Brief Psychiatric Rating Scale. Maximum score 126. Higher score indicates greater psychiatric difficulties. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in BPRS score (Mean)
Paroxetine-9.0
Venlafaxine Extended Release-9.8
Placebo-4.4

Change in Geriatric Depression Rating Scale (GDS)

Geriatric Depression Scale ranges from 0-30. Higher score indicates more severe depression. 0-9 normal, 10-19 mild depression, 20-30 severe depression. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in GDS score (Mean)
Paroxetine-6.9
Venlafaxine Extended Release-6.9
Placebo-2.8

Change in Hamilton Depression Rating Scale (HAM-D) Scores

Change in Hamilton Rating Scale for Depression over 12 weeks. Hamilton Depression Rating Scale ranges from 0-50. Higher scores represent more significant depression. Mild depression ranges from 8-13, moderate depression from 14-18, severe 19-22 and very severe any score over 23. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in HAM-D score (Mean)
Paroxetine-13.0
Venlafaxine Extended Release-11.0
Placebo-6.8

Change in Montgomery-Asberg Depression Rating Scale (MADRS)

Montgomery-Asberg Depression Rating Scale ranges from 0-60. Higher score indicates more severe depression. 0-6 normal, 7-19 mild depression, 20-34 moderate depression, greater than 34 severe depression. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in MADRS score (Mean)
Paroxetine-13.6
Venlafaxine Extended Release-10.9
Placebo-6.6

Change in Parkinson's Disease Questionnaire (PDQ) - 39 - Emotional Well-Being

Parkinson's Disease Questionnaire (PDQ-39) - Emotional Well-Being maximum score 24, minimum score of 0.Lower score indicates a better perceived health status. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in PDQ-39 Emotional score (Mean)
Paroxetine-21.4
Venlafaxine Extended Release-20.7
Placebo-10.9

Change in Parkinson's Disease Questionnaire (PDQ) - 39 - Overall

Parkinson's Disease Questionnaire (PDQ-39) Total. Range 0-100. Lower score indicates a better perceived health status. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in PDQ-39 score (Mean)
Paroxetine-8.0
Venlafaxine Extended Release-8.4
Placebo-5.3

Change in Pittsburgh Sleep Quality Index (PSQI)

Pittsburgh Sleep Quality Index scores range from 0-21, with higher scores indicating severe sleep difficulties. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in PQSI score (Mean)
Paroxetine-2.1
Venlafaxine Extended Release-2.6
Placebo-1.1

Change in Short Form 36 Health Survey - Mental Component Summary

Short Form 36 Health Survey. Range 0-100. Higher score indicates a better perceived quality of life. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in SF-36 mental score (Mean)
Paroxetine11.4
Venlafaxine Extended Release9.5
Placebo4.8

Change in Short Form 36 Health Survey - Mental Health

Short Form 36 Health Survey - Mental Health subscale ranges from 0-100. Higher score indicates a better perceived quality of life. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in SF-36 Mental Health score (Mean)
Paroxetine16.7
Venlafaxine Extended Release17.4
Placebo9.7

Change in Short Form 36 Health Survey - Role-Emotional

Short Form 36 Health Survey - Emotional subscale ranges from 0-100. Higher score indicates a better perceived quality of life. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in SF-36 Role score (Mean)
Paroxetine39.5
Venlafaxine Extended Release26.9
Placebo12.7

Change in Short Form 36 Health Survey - Vitality

Short Form 36 Health Survey - Vitality subscale ranges from 0-100. Higher score indicates a better perceived quality of life. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in SF-36 vitality score (Mean)
Paroxetine13.5
Venlafaxine Extended Release9.1
Placebo4.7

Change in Snaith Clinical Anxiety Scale (CAS)

Snaith Clinical Anxiety Scale. Range 0-21. Higher scores indicate increased anxiety. Score greater than 8 indicates clinical anxiety. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in CAS score (Mean)
Paroxetine-3.6
Venlafaxine Extended Release-3.2
Placebo-2.4

Change in Unified Parkinson's Disease Rating Scale (UPDRS)

Unified Parkinson's Disease Rating Scale. Higher score indicates more severe Parkinson's disease symptoms. Total maximum = 176. Mental maximum = 52, Activities of Daily Living maximum = 52, Motor maximum = 72. Minimum = 0. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in UPDRS score (Mean)
Paroxetine-8.7
Venlafaxine Extended Release-7.0
Placebo-4.3

Change in Unified Parkinson's Disease Rating Scale (UPDRS) - Bulbar

Unified Parkinson's Disease Rating Scale - Bulbar maximum score 24, minimum score of 0. Higher score indicates more severe Parkinson's disease symptoms. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in UPDRS-Bulbar score (Mean)
Paroxetine-1.4
Venlafaxine Extended Release-1.4
Placebo-0.5

Change in Unified Parkinson's Disease Rating Scale (UPDRS) - Motor

Unified Parkinson's Disease Rating Scale - Motor has a maximum score of 72, minimum score of 0. Higher score indicates more severe Parkinson's disease symptoms. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in UPDRS-motor score (Mean)
Paroxetine-4.3
Venlafaxine Extended Release-2.0
Placebo-1.0

Change in Unified Parkinson's Disease Rating Scale (UPDRS) - Tremor

Unified Parkinson's Disease Rating Scale - Tremor subscale ranges from 0-23. Higher score indicates more severe Parkinson's disease symptoms. (NCT00086190)
Timeframe: from the beginning (0 weeks) to end (12 weeks) of the double-blind phase

InterventionChange in UPDRS-tremor score (Mean)
Paroxetine0.4
Venlafaxine Extended Release0.5
Placebo-0.6

Reviews

6 reviews available for doxepin and Depressive Disorder

ArticleYear
Antidepressant-related erectile dysfunction: management via avoidance, switching antidepressants, antidotes, and adaptation.
    The Journal of clinical psychiatry, 2003, Volume: 64 Suppl 10

    Topics: Antidepressive Agents; Bupropion; Controlled Clinical Trials as Topic; Depressive Disorder; Doxepin;

2003
Antidepressant-related erectile dysfunction: management via avoidance, switching antidepressants, antidotes, and adaptation.
    The Journal of clinical psychiatry, 2003, Volume: 64 Suppl 10

    Topics: Antidepressive Agents; Bupropion; Controlled Clinical Trials as Topic; Depressive Disorder; Doxepin;

2003
Review of clinical and animal studies comparing the cardiovascular effects of doxepin and other tricyclic antidepressants.
    The American journal of psychiatry, 1983, Volume: 140, Issue:8

    Topics: Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Blood Pressure; Cardiovascular Syst

1983
Review of clinical and animal studies comparing the cardiovascular effects of doxepin and other tricyclic antidepressants.
    The American journal of psychiatry, 1983, Volume: 140, Issue:8

    Topics: Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Blood Pressure; Cardiovascular Syst

1983
Doxepin as an adjunct in the treatment of chronic pain.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:8 Pt 2

    Topics: Chronic Disease; Clinical Trials as Topic; Depression; Depressive Disorder; Doxepin; Humans; Hydroxy

1982
Doxepin as an adjunct in the treatment of chronic pain.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:8 Pt 2

    Topics: Chronic Disease; Clinical Trials as Topic; Depression; Depressive Disorder; Doxepin; Humans; Hydroxy

1982
Effects of antidepressants on human performance: a review.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:2

    Topics: Age Factors; Amitriptyline; Antidepressive Agents; Depressive Disorder; Doxepin; Humans; Imipramine;

1990
Effects of antidepressants on human performance: a review.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:2

    Topics: Age Factors; Amitriptyline; Antidepressive Agents; Depressive Disorder; Doxepin; Humans; Imipramine;

1990
Tricyclic antidepressants for medically ill geriatric patients.
    The Journal of clinical psychiatry, 1989, Volume: 50 Suppl

    Topics: Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Doxepin; Geriatrics; Human

1989
Tricyclic antidepressants for medically ill geriatric patients.
    The Journal of clinical psychiatry, 1989, Volume: 50 Suppl

    Topics: Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Doxepin; Geriatrics; Human

1989
Steady-state kinetics of doxepin and imipramine in Saudi patients with interethnic comparison.
    Psychopharmacology, 1988, Volume: 95, Issue:1

    Topics: Adolescent; Adult; Depressive Disorder; Doxepin; Europe; Female; Humans; Imipramine; Male; Middle Ag

1988
Steady-state kinetics of doxepin and imipramine in Saudi patients with interethnic comparison.
    Psychopharmacology, 1988, Volume: 95, Issue:1

    Topics: Adolescent; Adult; Depressive Disorder; Doxepin; Europe; Female; Humans; Imipramine; Male; Middle Ag

1988

Trials

59 trials available for doxepin and Depressive Disorder

ArticleYear
Therapeutic drug monitoring of tricyclic antidepressants: how does it work under clinical conditions?
    Pharmacopsychiatry, 2003, Volume: 36, Issue:3

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Drug Monitoring; Fema

2003
Therapeutic drug monitoring of tricyclic antidepressants: how does it work under clinical conditions?
    Pharmacopsychiatry, 2003, Volume: 36, Issue:3

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Drug Monitoring; Fema

2003
Motor cortex excitability after vagus nerve stimulation in major depression.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Adult; Benzodiazepines; Citalopram; Clomipramine; Clozapine; Depressive Disorder; Doxepin; Drug Ther

2007
Motor cortex excitability after vagus nerve stimulation in major depression.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Adult; Benzodiazepines; Citalopram; Clomipramine; Clozapine; Depressive Disorder; Doxepin; Drug Ther

2007
A randomized controlled clinical trial comparing "guideline exposed" and "guideline naive" physicians in respect to dosage selection and treatment outcome with doxepin in depressive disorders.
    Pharmacopsychiatry, 2007, Volume: 40, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Depressive Disorder; D

2007
A randomized controlled clinical trial comparing "guideline exposed" and "guideline naive" physicians in respect to dosage selection and treatment outcome with doxepin in depressive disorders.
    Pharmacopsychiatry, 2007, Volume: 40, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Depressive Disorder; D

2007
The role of chemotherapy in managing potentially suicidal patients.
    Diseases of the nervous system, 1974, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Crisis Intervention; Depressive

1974
The role of chemotherapy in managing potentially suicidal patients.
    Diseases of the nervous system, 1974, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Crisis Intervention; Depressive

1974
Benzodiazepines as antidepressants. A triazolobenzodiazepine used to treat depression.
    Modern problems of pharmacopsychiatry, 1982, Volume: 18

    Topics: Alprazolam; Amitriptyline; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Depressiv

1982
Benzodiazepines as antidepressants. A triazolobenzodiazepine used to treat depression.
    Modern problems of pharmacopsychiatry, 1982, Volume: 18

    Topics: Alprazolam; Amitriptyline; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Depressiv

1982
Double-blind clinical study comparing alprazolam and doxepin in primary unipolar depression.
    Journal of affective disorders, 1984, Volume: 7, Issue:3-4

    Topics: Adolescent; Adult; Aged; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic;

1984
Double-blind clinical study comparing alprazolam and doxepin in primary unipolar depression.
    Journal of affective disorders, 1984, Volume: 7, Issue:3-4

    Topics: Adolescent; Adult; Aged; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic;

1984
Comparative cardiac effects of maprotiline and doxepin in elderly depressed patients.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:11

    Topics: Aged; Angina Pectoris; Anthracenes; Blood Pressure; Cardiac Complexes, Premature; Clinical Trials as

1984
Comparative cardiac effects of maprotiline and doxepin in elderly depressed patients.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:11

    Topics: Aged; Angina Pectoris; Anthracenes; Blood Pressure; Cardiac Complexes, Premature; Clinical Trials as

1984
Doxepin's effects on chronic pain and depression: a controlled study.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:3 Pt 2

    Topics: beta-Endorphin; Chronic Disease; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method;

1984
Doxepin's effects on chronic pain and depression: a controlled study.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:3 Pt 2

    Topics: beta-Endorphin; Chronic Disease; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method;

1984
Antidepressants in concomitant chronic back pain and depression: doxepin and desipramine compared.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:3 Pt 2

    Topics: Adult; Anxiety Disorders; Back Pain; beta-Endorphin; Chronic Disease; Clinical Trials as Topic; Depr

1984
Antidepressants in concomitant chronic back pain and depression: doxepin and desipramine compared.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:3 Pt 2

    Topics: Adult; Anxiety Disorders; Back Pain; beta-Endorphin; Chronic Disease; Clinical Trials as Topic; Depr

1984
Pretreatment orthostatic hypotension in geriatric depression: predictor of response to imipramine and doxepin.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:6

    Topics: Aged; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans; H

1983
Pretreatment orthostatic hypotension in geriatric depression: predictor of response to imipramine and doxepin.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:6

    Topics: Aged; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans; H

1983
Therapeutic superiority of maprotiline versus doxepin in geriatric depression.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:12

    Topics: Anthracenes; Clinical Trials as Topic; Constipation; Depressive Disorder; Dizziness; Double-Blind Me

1983
Therapeutic superiority of maprotiline versus doxepin in geriatric depression.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:12

    Topics: Anthracenes; Clinical Trials as Topic; Constipation; Depressive Disorder; Dizziness; Double-Blind Me

1983
Long-term treatment of chronic depression: 15-year experience with doxepin HCl.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:3 Pt 2

    Topics: Adult; Aged; Ambulatory Care; Chronic Disease; Clinical Trials as Topic; Depressive Disorder; Doxepi

1984
Long-term treatment of chronic depression: 15-year experience with doxepin HCl.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:3 Pt 2

    Topics: Adult; Aged; Ambulatory Care; Chronic Disease; Clinical Trials as Topic; Depressive Disorder; Doxepi

1984
A comparison of clomipramine and doxepin in neurotic depression.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:8

    Topics: Adolescent; Adult; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method;

1984
A comparison of clomipramine and doxepin in neurotic depression.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:8

    Topics: Adolescent; Adult; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method;

1984
Lithium carbonate addition in tricyclic antidepressant-resistant unipolar depression. Correlations with the neurobiologic actions of tricyclic antidepressant drugs and lithium ion on the serotonin system.
    Archives of general psychiatry, 1983, Volume: 40, Issue:12

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive D

1983
Lithium carbonate addition in tricyclic antidepressant-resistant unipolar depression. Correlations with the neurobiologic actions of tricyclic antidepressant drugs and lithium ion on the serotonin system.
    Archives of general psychiatry, 1983, Volume: 40, Issue:12

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive D

1983
Amitriptyline-perphenazine and doxepin in depressed outpatients: a controlled double-blind study.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:10

    Topics: Adult; Ambulatory Care; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind M

1982
Amitriptyline-perphenazine and doxepin in depressed outpatients: a controlled double-blind study.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:10

    Topics: Adult; Ambulatory Care; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind M

1982
Mianserin and doxepin in the treatment of outpatient depression with anxiety.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 2

    Topics: Adult; Aged; Anxiety Disorders; Depressive Disorder; Dibenzazepines; Doxepin; Electrocardiography; F

1983
Mianserin and doxepin in the treatment of outpatient depression with anxiety.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 2

    Topics: Adult; Aged; Anxiety Disorders; Depressive Disorder; Dibenzazepines; Doxepin; Electrocardiography; F

1983
Doxepin and hydroxyzine in treating anxiety: effects of failure and motivation on cognitive performance.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:2

    Topics: Adult; Anxiety Disorders; Cognition; Depressive Disorder; Doxepin; Humans; Hydroxyzine; Male; Middle

1983
Doxepin and hydroxyzine in treating anxiety: effects of failure and motivation on cognitive performance.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:2

    Topics: Adult; Anxiety Disorders; Cognition; Depressive Disorder; Doxepin; Humans; Hydroxyzine; Male; Middle

1983
Onset of action of amoxapine and doxepin in outpatients with "mixed anxiety/depression".
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:7

    Topics: Adult; Ambulatory Care; Amoxapine; Anxiety Disorders; Constipation; Depressive Disorder; Dibenzoxaze

1983
Onset of action of amoxapine and doxepin in outpatients with "mixed anxiety/depression".
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:7

    Topics: Adult; Ambulatory Care; Amoxapine; Anxiety Disorders; Constipation; Depressive Disorder; Dibenzoxaze

1983
Stimulus intensity control in depression: a study of the comparative effect of doxepin and amitriptyline on cortical evoked potentials.
    The Australian and New Zealand journal of psychiatry, 1980, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Aged; Amitriptyline; Auditory Perception; Depressive Disorder; Doxepin; Electroen

1980
Stimulus intensity control in depression: a study of the comparative effect of doxepin and amitriptyline on cortical evoked potentials.
    The Australian and New Zealand journal of psychiatry, 1980, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Aged; Amitriptyline; Auditory Perception; Depressive Disorder; Doxepin; Electroen

1980
Viloxazine in the treatment of depressive neurosis: a controlled clinical study with doxepin and placebo.
    The British journal of psychiatry : the journal of mental science, 1980, Volume: 137

    Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans;

1980
Viloxazine in the treatment of depressive neurosis: a controlled clinical study with doxepin and placebo.
    The British journal of psychiatry : the journal of mental science, 1980, Volume: 137

    Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans;

1980
Cardiovascular effects of tricyclic antidepressants in depressed patients with chronic heart disease.
    The New England journal of medicine, 1982, Apr-22, Volume: 306, Issue:16

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Blood Pressure; Chronic Disease

1982
Cardiovascular effects of tricyclic antidepressants in depressed patients with chronic heart disease.
    The New England journal of medicine, 1982, Apr-22, Volume: 306, Issue:16

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Blood Pressure; Chronic Disease

1982
Double-blind comparison of doxepin and desipramine in patients with primary affective disorder.
    Acta psychiatrica Scandinavica, 1982, Volume: 65, Issue:4

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blin

1982
Double-blind comparison of doxepin and desipramine in patients with primary affective disorder.
    Acta psychiatrica Scandinavica, 1982, Volume: 65, Issue:4

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blin

1982
A collaborative study of a new antidepressant, viloxazine, in neurotic and endogenous depressives.
    International pharmacopsychiatry, 1982, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Dizziness; Doxepin;

1982
A collaborative study of a new antidepressant, viloxazine, in neurotic and endogenous depressives.
    International pharmacopsychiatry, 1982, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Dizziness; Doxepin;

1982
Doxepin as an adjunct in the treatment of chronic pain.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:8 Pt 2

    Topics: Chronic Disease; Clinical Trials as Topic; Depression; Depressive Disorder; Doxepin; Humans; Hydroxy

1982
Doxepin as an adjunct in the treatment of chronic pain.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:8 Pt 2

    Topics: Chronic Disease; Clinical Trials as Topic; Depression; Depressive Disorder; Doxepin; Humans; Hydroxy

1982
Doxepin as adjunctive therapy for depressed methadone maintenance patients: a double-blind study.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:11

    Topics: Adult; Depressive Disorder; Double-Blind Method; Doxepin; Drug Therapy, Combination; Female; Humans;

1982
Doxepin as adjunctive therapy for depressed methadone maintenance patients: a double-blind study.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:11

    Topics: Adult; Depressive Disorder; Double-Blind Method; Doxepin; Drug Therapy, Combination; Female; Humans;

1982
Specific responses to imipramine and doxepin in psychoneurotic depressed patients with sleep disturbance.
    The Journal of clinical psychiatry, 1981, Volume: 42, Issue:7

    Topics: Adult; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans; Imipramine; Male; Random A

1981
Specific responses to imipramine and doxepin in psychoneurotic depressed patients with sleep disturbance.
    The Journal of clinical psychiatry, 1981, Volume: 42, Issue:7

    Topics: Adult; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans; Imipramine; Male; Random A

1981
Clomipramine and doxepin in depressive neurosis. Plasma levels and therapeutic response.
    Archives of general psychiatry, 1980, Volume: 37, Issue:11

    Topics: Adult; Clomipramine; Depressive Disorder; Doxepin; Female; Humans; Male; Reaction Time; Tryptophan

1980
Clomipramine and doxepin in depressive neurosis. Plasma levels and therapeutic response.
    Archives of general psychiatry, 1980, Volume: 37, Issue:11

    Topics: Adult; Clomipramine; Depressive Disorder; Doxepin; Female; Humans; Male; Reaction Time; Tryptophan

1980
A double-blind comparison of moclobemide and doxepin in depressed general practice patients.
    Acta psychiatrica Scandinavica, 1995, Volume: 92, Issue:2

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzamides; Depressive Disorder; Dose-Respo

1995
A double-blind comparison of moclobemide and doxepin in depressed general practice patients.
    Acta psychiatrica Scandinavica, 1995, Volume: 92, Issue:2

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzamides; Depressive Disorder; Dose-Respo

1995
Panic disorder with or without concomitant depression 5 years after treatment: a prospective follow-up.
    Journal of affective disorders, 1995, May-17, Volume: 34, Issue:2

    Topics: Adult; Agoraphobia; Combined Modality Therapy; Comorbidity; Depressive Disorder; Doxepin; Female; Fo

1995
Panic disorder with or without concomitant depression 5 years after treatment: a prospective follow-up.
    Journal of affective disorders, 1995, May-17, Volume: 34, Issue:2

    Topics: Adult; Agoraphobia; Combined Modality Therapy; Comorbidity; Depressive Disorder; Doxepin; Female; Fo

1995
A comparison of the cardiac safety and therapeutic efficacy of trimipramine versus doxepin in geriatric depressed patients.
    Journal of the American Geriatrics Society, 1993, Volume: 41, Issue:8

    Topics: Age Factors; Aged; Analysis of Variance; Blood Pressure; Cardiac Complexes, Premature; Cognition; De

1993
A comparison of the cardiac safety and therapeutic efficacy of trimipramine versus doxepin in geriatric depressed patients.
    Journal of the American Geriatrics Society, 1993, Volume: 41, Issue:8

    Topics: Age Factors; Aged; Analysis of Variance; Blood Pressure; Cardiac Complexes, Premature; Cognition; De

1993
The effect of amitriptyline, doxepin, fluvoxamine, and paroxetine treatment on heart rate variability.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:6

    Topics: Adult; Aged; Amitriptyline; Depressive Disorder; Dose-Response Relationship, Drug; Doxepin; Drug Adm

1994
The effect of amitriptyline, doxepin, fluvoxamine, and paroxetine treatment on heart rate variability.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:6

    Topics: Adult; Aged; Amitriptyline; Depressive Disorder; Dose-Response Relationship, Drug; Doxepin; Drug Adm

1994
Dothiepin versus doxepin in major depression: results of a multicenter, placebo-controlled trial. Prothiaden Collaborative Study Group.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:6

    Topics: Adult; Aged; Ambulatory Care; Depressive Disorder; Dothiepin; Double-Blind Method; Doxepin; Drug Adm

1994
Dothiepin versus doxepin in major depression: results of a multicenter, placebo-controlled trial. Prothiaden Collaborative Study Group.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:6

    Topics: Adult; Aged; Ambulatory Care; Depressive Disorder; Dothiepin; Double-Blind Method; Doxepin; Drug Adm

1994
A double-blind comparison of amitriptylinoxide versus doxepine in the treatment of severe depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:3

    Topics: Adult; Aged; Amitriptyline; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans; Male;

1994
A double-blind comparison of amitriptylinoxide versus doxepine in the treatment of severe depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:3

    Topics: Adult; Aged; Amitriptyline; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans; Male;

1994
Outcome of panic disorder with or without concomitant depression: A 2-year prospective follow-up study.
    The American journal of psychiatry, 1993, Volume: 150, Issue:12

    Topics: Adult; Ambulatory Care; Antidepressive Agents; Combined Modality Therapy; Comorbidity; Depressive Di

1993
Outcome of panic disorder with or without concomitant depression: A 2-year prospective follow-up study.
    The American journal of psychiatry, 1993, Volume: 150, Issue:12

    Topics: Adult; Ambulatory Care; Antidepressive Agents; Combined Modality Therapy; Comorbidity; Depressive Di

1993
A comparison study of moclobemide and doxepin in major depression with special reference to effects on sexual dysfunction.
    International clinical psychopharmacology, 1993, Volume: 7, Issue:3-4

    Topics: Adult; Benzamides; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Doxep

1993
A comparison study of moclobemide and doxepin in major depression with special reference to effects on sexual dysfunction.
    International clinical psychopharmacology, 1993, Volume: 7, Issue:3-4

    Topics: Adult; Benzamides; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Doxep

1993
Fluctuation of symptoms and social functioning in panic disorder with or without concomitant depression. A 5-year prospective follow-up.
    Psychopathology, 1995, Volume: 28, Issue:5

    Topics: Agoraphobia; Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder; Doxepin; Follow-Up

1995
Fluctuation of symptoms and social functioning in panic disorder with or without concomitant depression. A 5-year prospective follow-up.
    Psychopathology, 1995, Volume: 28, Issue:5

    Topics: Agoraphobia; Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder; Doxepin; Follow-Up

1995
Low serum levels of tricyclic antidepressants in amitriptyline- and doxepin-treated inpatients with depressive syndromes are associated with nonresponse.
    Pharmacopsychiatry, 1996, Volume: 29, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Amitriptyline; Antidepressive Agents, Tricyclic; Body Mass In

1996
Low serum levels of tricyclic antidepressants in amitriptyline- and doxepin-treated inpatients with depressive syndromes are associated with nonresponse.
    Pharmacopsychiatry, 1996, Volume: 29, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Amitriptyline; Antidepressive Agents, Tricyclic; Body Mass In

1996
A double-blind study comparing the efficacy and tolerability of mirtazapine and doxepin in patients with major depression.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1995, Volume: 5, Issue:4

    Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Doxep

1995
A double-blind study comparing the efficacy and tolerability of mirtazapine and doxepin in patients with major depression.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1995, Volume: 5, Issue:4

    Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Doxep

1995
Electrocardiographic effects of fluoxetine and doxepin in patients with major depressive disorder.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disord

1997
Electrocardiographic effects of fluoxetine and doxepin in patients with major depressive disorder.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disord

1997
On the problems of switching from intravenous to oral administration in drug treatment of endogenous depression--a placebo-controlled double-blind trial with doxepin.
    Pharmacopsychiatry, 1997, Volume: 30, Issue:2

    Topics: Administration, Oral; Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Met

1997
On the problems of switching from intravenous to oral administration in drug treatment of endogenous depression--a placebo-controlled double-blind trial with doxepin.
    Pharmacopsychiatry, 1997, Volume: 30, Issue:2

    Topics: Administration, Oral; Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Met

1997
Pulse-dosing and conventional application of doxepin: effects on psychopathology and hypothalamus-pituitary-adrenal (HPA) system.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:3

    Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Dexamethasone; Double-Blind Method; Do

1997
Pulse-dosing and conventional application of doxepin: effects on psychopathology and hypothalamus-pituitary-adrenal (HPA) system.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:3

    Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Dexamethasone; Double-Blind Method; Do

1997
Doxepin and its metabolites in plasma and cerebrospinal fluid in depressed patients.
    Psychopharmacology, 1997, Volume: 131, Issue:1

    Topics: Adult; Cerebrospinal Fluid; Depressive Disorder; Doxepin; Female; Humans; Male; Middle Aged

1997
Doxepin and its metabolites in plasma and cerebrospinal fluid in depressed patients.
    Psychopharmacology, 1997, Volume: 131, Issue:1

    Topics: Adult; Cerebrospinal Fluid; Depressive Disorder; Doxepin; Female; Humans; Male; Middle Aged

1997
Autonomic correlates of antidepressant treatment using heart-rate variability analysis.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1998, Volume: 43, Issue:2

    Topics: Analysis of Variance; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Au

1998
Autonomic correlates of antidepressant treatment using heart-rate variability analysis.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1998, Volume: 43, Issue:2

    Topics: Analysis of Variance; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Au

1998
Effectiveness of fluoxetine and doxepin in treatment of melancholia in depressed patients.
    Depression and anxiety, 1998, Volume: 7, Issue:2

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disord

1998
Effectiveness of fluoxetine and doxepin in treatment of melancholia in depressed patients.
    Depression and anxiety, 1998, Volume: 7, Issue:2

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disord

1998
Two combined, multicenter double-blind studies of paroxetine and doxepin in geriatric patients with major depression.
    The Journal of clinical psychiatry, 1992, Volume: 53 Suppl

    Topics: Age Factors; Aged; Ambulatory Care; Antidepressive Agents; Depressive Disorder; Double-Blind Method;

1992
Two combined, multicenter double-blind studies of paroxetine and doxepin in geriatric patients with major depression.
    The Journal of clinical psychiatry, 1992, Volume: 53 Suppl

    Topics: Age Factors; Aged; Ambulatory Care; Antidepressive Agents; Depressive Disorder; Double-Blind Method;

1992
[Intravenous versus oral treatment of endogenously depressed patients with doxepin--a double-blind study with plasma level determination].
    Wiener medizinische Wochenschrift (1946), 1989, Nov-30, Volume: 139, Issue:22

    Topics: Administration, Oral; Adult; Aged; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans

1989
[Intravenous versus oral treatment of endogenously depressed patients with doxepin--a double-blind study with plasma level determination].
    Wiener medizinische Wochenschrift (1946), 1989, Nov-30, Volume: 139, Issue:22

    Topics: Administration, Oral; Adult; Aged; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans

1989
Comparative trial of trimipramine versus doxepin in depressed hospitalised patients.
    Drugs, 1989, Volume: 38 Suppl 1

    Topics: Clinical Trials as Topic; Depressive Disorder; Dibenzazepines; Double-Blind Method; Doxepin; Female;

1989
Comparative trial of trimipramine versus doxepin in depressed hospitalised patients.
    Drugs, 1989, Volume: 38 Suppl 1

    Topics: Clinical Trials as Topic; Depressive Disorder; Dibenzazepines; Double-Blind Method; Doxepin; Female;

1989
A double-blind parallel study to compare fluoxetine with doxepin in the treatment of major depressive disorders.
    International clinical psychopharmacology, 1989, Volume: 4 Suppl 1

    Topics: Adult; Depressive Disorder; Double-Blind Method; Doxepin; Female; Fluoxetine; Humans; Male; Middle A

1989
A double-blind parallel study to compare fluoxetine with doxepin in the treatment of major depressive disorders.
    International clinical psychopharmacology, 1989, Volume: 4 Suppl 1

    Topics: Adult; Depressive Disorder; Double-Blind Method; Doxepin; Female; Fluoxetine; Humans; Male; Middle A

1989
A comparative trial of the antidepressant, anxiolytic, and cardiovascular effects of trimipramine and doxepin in depressed hospitalized patients.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:3

    Topics: Anorexia; Anti-Anxiety Agents; Clinical Trials as Topic; Depressive Disorder; Dibenzazepines; Dizzin

1985
A comparative trial of the antidepressant, anxiolytic, and cardiovascular effects of trimipramine and doxepin in depressed hospitalized patients.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:3

    Topics: Anorexia; Anti-Anxiety Agents; Clinical Trials as Topic; Depressive Disorder; Dibenzazepines; Dizzin

1985
Alprazolam, amitriptyline, doxepin, and placebo in the treatment of depression.
    Archives of general psychiatry, 1985, Volume: 42, Issue:2

    Topics: Adult; Alcoholism; Alprazolam; Ambulatory Care; Amitriptyline; Anti-Anxiety Agents; Benzodiazepines;

1985
Alprazolam, amitriptyline, doxepin, and placebo in the treatment of depression.
    Archives of general psychiatry, 1985, Volume: 42, Issue:2

    Topics: Adult; Alcoholism; Alprazolam; Ambulatory Care; Amitriptyline; Anti-Anxiety Agents; Benzodiazepines;

1985
Tricyclic antidepressants for chronic low-back pain. Mechanisms of action and predictors of response.
    Spine, 1986, Volume: 11, Issue:7

    Topics: Adult; Back Pain; Chronic Disease; Clinical Trials as Topic; Depressive Disorder; Desipramine; Doubl

1986
Tricyclic antidepressants for chronic low-back pain. Mechanisms of action and predictors of response.
    Spine, 1986, Volume: 11, Issue:7

    Topics: Adult; Back Pain; Chronic Disease; Clinical Trials as Topic; Depressive Disorder; Desipramine; Doubl

1986
Double-blind comparison of doxepin versus bupropion in outpatients with a major depressive disorder.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:1

    Topics: Adult; Aged; Antidepressive Agents; Body Weight; Bupropion; Clinical Trials as Topic; Depressive Dis

1986
Double-blind comparison of doxepin versus bupropion in outpatients with a major depressive disorder.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:1

    Topics: Adult; Aged; Antidepressive Agents; Body Weight; Bupropion; Clinical Trials as Topic; Depressive Dis

1986
Antidepressant plasma levels and clinical response in depressed patients treated with oxaprotiline and doxepin.
    International clinical psychopharmacology, 1988, Volume: 3, Issue:3

    Topics: Adult; Antidepressive Agents; Depressive Disorder; Doxepin; Female; Humans; Male; Maprotiline; Middl

1988
Antidepressant plasma levels and clinical response in depressed patients treated with oxaprotiline and doxepin.
    International clinical psychopharmacology, 1988, Volume: 3, Issue:3

    Topics: Adult; Antidepressive Agents; Depressive Disorder; Doxepin; Female; Humans; Male; Maprotiline; Middl

1988
Doxepin treatment of depressed patients with chronic obstructive pulmonary disease.
    Archives of internal medicine, 1986, Volume: 146, Issue:7

    Topics: Aged; Anxiety; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Doxepin; Emotions

1986
Doxepin treatment of depressed patients with chronic obstructive pulmonary disease.
    Archives of internal medicine, 1986, Volume: 146, Issue:7

    Topics: Aged; Anxiety; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Doxepin; Emotions

1986
Clovoxamine and doxepin in major depressive disorder: a double-blind controlled trial.
    The British journal of psychiatry : the journal of mental science, 1986, Volume: 148

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Blood Pressure; Body Weight; Clinical Trials as Topi

1986
Clovoxamine and doxepin in major depressive disorder: a double-blind controlled trial.
    The British journal of psychiatry : the journal of mental science, 1986, Volume: 148

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Blood Pressure; Body Weight; Clinical Trials as Topi

1986
Effective low dose tricyclic antidepressant treatment for depressed geriatric rehabilitation patients. A double-blind study.
    Journal of the American Geriatrics Society, 1986, Volume: 34, Issue:6

    Topics: Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Doxepin; Female; H

1986
Effective low dose tricyclic antidepressant treatment for depressed geriatric rehabilitation patients. A double-blind study.
    Journal of the American Geriatrics Society, 1986, Volume: 34, Issue:6

    Topics: Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Doxepin; Female; H

1986
Double-blind comparative trials of fluoxetine and doxepin in geriatric patients with major depressive disorder.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:3 Pt 2

    Topics: Age Factors; Aged; Anxiety; Blood Pressure; Body Weight; Clinical Trials as Topic; Depressive Disord

1985
Double-blind comparative trials of fluoxetine and doxepin in geriatric patients with major depressive disorder.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:3 Pt 2

    Topics: Age Factors; Aged; Anxiety; Blood Pressure; Body Weight; Clinical Trials as Topic; Depressive Disord

1985
Behavioral effects of tricyclic drugs in depressed inpatients.
    Journal of consulting and clinical psychology, 1985, Volume: 53, Issue:1

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Female; Humans

1985
Behavioral effects of tricyclic drugs in depressed inpatients.
    Journal of consulting and clinical psychology, 1985, Volume: 53, Issue:1

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Female; Humans

1985
Orthostatic effect of imipramine and doxepin in depressed geriatric outpatients.
    Journal of clinical psychopharmacology, 1985, Volume: 5, Issue:2

    Topics: Age Factors; Aged; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans; Hypotension, O

1985
Orthostatic effect of imipramine and doxepin in depressed geriatric outpatients.
    Journal of clinical psychopharmacology, 1985, Volume: 5, Issue:2

    Topics: Age Factors; Aged; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans; Hypotension, O

1985

Other Studies

60 other studies available for doxepin and Depressive Disorder

ArticleYear
Doxepin-Associated Hypoglycemia in an Ambulatory Nondiabetic Patient.
    The primary care companion for CNS disorders, 2023, 07-06, Volume: 25, Issue:4

    Topics: Depressive Disorder; Doxepin; Humans; Hypoglycemia

2023
Doxepin-Associated Hypoglycemia in an Ambulatory Nondiabetic Patient.
    The primary care companion for CNS disorders, 2023, 07-06, Volume: 25, Issue:4

    Topics: Depressive Disorder; Doxepin; Humans; Hypoglycemia

2023
Comparative efficacy and acceptability of antidepressant treatment in poststroke depression: a multiple-treatments meta-analysis.
    BMJ open, 2017, Aug-03, Volume: 7, Issue:8

    Topics: Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Depression; Depre

2017
Comparative efficacy and acceptability of antidepressant treatment in poststroke depression: a multiple-treatments meta-analysis.
    BMJ open, 2017, Aug-03, Volume: 7, Issue:8

    Topics: Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Depression; Depre

2017
Doxepin concentrations in plasma and cerebrospinal fluid.
    Journal of neural transmission (Vienna, Austria : 1996), 2011, Volume: 118, Issue:4

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Female; Humans; Male; M

2011
Doxepin concentrations in plasma and cerebrospinal fluid.
    Journal of neural transmission (Vienna, Austria : 1996), 2011, Volume: 118, Issue:4

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Female; Humans; Male; M

2011
Psychobiological markers in coexisting pain and depression: toward a unified theory.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:8 Pt 2

    Topics: Anxiety Disorders; Brain; Depressive Disorder; Doxepin; Humans; Hydroxyindoleacetic Acid; Methoxyhyd

1982
Psychobiological markers in coexisting pain and depression: toward a unified theory.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:8 Pt 2

    Topics: Anxiety Disorders; Brain; Depressive Disorder; Doxepin; Humans; Hydroxyindoleacetic Acid; Methoxyhyd

1982
Anxiety in depression.
    Clinical therapeutics, 1984, Volume: 6, Issue:4

    Topics: Adult; Anxiety Disorders; Combined Modality Therapy; Depressive Disorder; Dose-Response Relationship

1984
Anxiety in depression.
    Clinical therapeutics, 1984, Volume: 6, Issue:4

    Topics: Adult; Anxiety Disorders; Combined Modality Therapy; Depressive Disorder; Dose-Response Relationship

1984
Doxepin and tinnitus.
    Southern medical journal, 1983, Volume: 76, Issue:9

    Topics: Aged; Depressive Disorder; Doxepin; Female; Humans; Tinnitus

1983
Doxepin and tinnitus.
    Southern medical journal, 1983, Volume: 76, Issue:9

    Topics: Aged; Depressive Disorder; Doxepin; Female; Humans; Tinnitus

1983
Multiple-dose doxepin kinetics in depressed patients.
    Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:4

    Topics: Adult; Depressive Disorder; Dose-Response Relationship, Drug; Doxepin; Humans; Kinetics; Male; Middl

1983
Multiple-dose doxepin kinetics in depressed patients.
    Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:4

    Topics: Adult; Depressive Disorder; Dose-Response Relationship, Drug; Doxepin; Humans; Kinetics; Male; Middl

1983
Ventricular arrhythmias induced by doxepin and amitriptyline: case report.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:11

    Topics: Amitriptyline; Arrhythmias, Cardiac; Depressive Disorder; Doxepin; Humans; Male; Middle Aged

1983
Ventricular arrhythmias induced by doxepin and amitriptyline: case report.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:11

    Topics: Amitriptyline; Arrhythmias, Cardiac; Depressive Disorder; Doxepin; Humans; Male; Middle Aged

1983
Doxepin's cardiotoxicity reviewed.
    The American journal of psychiatry, 1984, Volume: 141, Issue:3

    Topics: Animals; Anxiety Disorders; Cardiovascular Diseases; Depressive Disorder; Doxepin; Humans; Research

1984
Doxepin's cardiotoxicity reviewed.
    The American journal of psychiatry, 1984, Volume: 141, Issue:3

    Topics: Animals; Anxiety Disorders; Cardiovascular Diseases; Depressive Disorder; Doxepin; Humans; Research

1984
The dexamethasone suppression test in depressive illness: clinical correlates.
    Psychoneuroendocrinology, 1982, Volume: 7, Issue:4

    Topics: Depressive Disorder; Desipramine; Dexamethasone; Diagnosis, Differential; Double-Blind Method; Doxep

1982
The dexamethasone suppression test in depressive illness: clinical correlates.
    Psychoneuroendocrinology, 1982, Volume: 7, Issue:4

    Topics: Depressive Disorder; Desipramine; Dexamethasone; Diagnosis, Differential; Double-Blind Method; Doxep

1982
Urinary 3-methoxy-4-hydroxyphenethylene glycol in the prediction of pain and depression relief with doxepin: preliminary findings.
    The Journal of nervous and mental disease, 1983, Volume: 171, Issue:1

    Topics: Adult; Anxiety Disorders; Depressive Disorder; Doxepin; Female; Glycols; Humans; Male; Methoxyhydrox

1983
Urinary 3-methoxy-4-hydroxyphenethylene glycol in the prediction of pain and depression relief with doxepin: preliminary findings.
    The Journal of nervous and mental disease, 1983, Volume: 171, Issue:1

    Topics: Adult; Anxiety Disorders; Depressive Disorder; Doxepin; Female; Glycols; Humans; Male; Methoxyhydrox

1983
Tricyclic antidepressants and supine, standing, and exercise plasma norepinephrine levels.
    Clinical pharmacology and therapeutics, 1983, Volume: 33, Issue:6

    Topics: Adult; Amitriptyline; Blood Pressure; Depressive Disorder; Doxepin; Epinephrine; Female; Heart Rate;

1983
Tricyclic antidepressants and supine, standing, and exercise plasma norepinephrine levels.
    Clinical pharmacology and therapeutics, 1983, Volume: 33, Issue:6

    Topics: Adult; Amitriptyline; Blood Pressure; Depressive Disorder; Doxepin; Epinephrine; Female; Heart Rate;

1983
Is amitriptyline + perphenazine superior to doxepin?
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5

    Topics: Ambulatory Care; Amitriptyline; Depressive Disorder; Doxepin; Drug Combinations; Drug Therapy, Combi

1983
Is amitriptyline + perphenazine superior to doxepin?
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5

    Topics: Ambulatory Care; Amitriptyline; Depressive Disorder; Doxepin; Drug Combinations; Drug Therapy, Combi

1983
Relationship between tricyclic antidepressant plasma levels and clinical response in patients treated with desipramine or doxepin.
    Acta psychiatrica Scandinavica, 1983, Volume: 67, Issue:6

    Topics: Adult; Depressive Disorder; Desipramine; Doxepin; Female; Humans; Male; Middle Aged; Random Allocati

1983
Relationship between tricyclic antidepressant plasma levels and clinical response in patients treated with desipramine or doxepin.
    Acta psychiatrica Scandinavica, 1983, Volume: 67, Issue:6

    Topics: Adult; Depressive Disorder; Desipramine; Doxepin; Female; Humans; Male; Middle Aged; Random Allocati

1983
Depression in a patient with dementia secondary to cerebrotendinous xanthomatosis.
    The Journal of nervous and mental disease, 1983, Volume: 171, Issue:9

    Topics: Depressive Disorder; Doxepin; Haloperidol; Humans; Lipidoses; Male; Middle Aged; Neurocognitive Diso

1983
Depression in a patient with dementia secondary to cerebrotendinous xanthomatosis.
    The Journal of nervous and mental disease, 1983, Volume: 171, Issue:9

    Topics: Depressive Disorder; Doxepin; Haloperidol; Humans; Lipidoses; Male; Middle Aged; Neurocognitive Diso

1983
The use of antidepressants with methadone in depressed maintenance patients.
    Annals of the New York Academy of Sciences, 1982, Volume: 398

    Topics: Depressive Disorder; Doxepin; Female; Humans; Imipramine; Male; Methadone; Middle Aged; Opioid-Relat

1982
The use of antidepressants with methadone in depressed maintenance patients.
    Annals of the New York Academy of Sciences, 1982, Volume: 398

    Topics: Depressive Disorder; Doxepin; Female; Humans; Imipramine; Male; Methadone; Middle Aged; Opioid-Relat

1982
TCA-induced mania: differences between switchers and nonswitchers.
    Biological psychiatry, 1982, Volume: 17, Issue:2

    Topics: Adult; Affective Disorders, Psychotic; Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic;

1982
TCA-induced mania: differences between switchers and nonswitchers.
    Biological psychiatry, 1982, Volume: 17, Issue:2

    Topics: Adult; Affective Disorders, Psychotic; Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic;

1982
The effects of doxepin HCl on sleep and depression.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:9

    Topics: Adult; Circadian Rhythm; Depressive Disorder; Dose-Response Relationship, Drug; Doxepin; Female; Hum

1982
The effects of doxepin HCl on sleep and depression.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:9

    Topics: Adult; Circadian Rhythm; Depressive Disorder; Dose-Response Relationship, Drug; Doxepin; Female; Hum

1982
Treating geriatric depression: a 26-week interim analysis.
    Journal of the American Geriatrics Society, 1982, Volume: 30, Issue:11

    Topics: Antidepressive Agents, Tricyclic; Behavior Therapy; Cognition; Depressive Disorder; Double-Blind Met

1982
Treating geriatric depression: a 26-week interim analysis.
    Journal of the American Geriatrics Society, 1982, Volume: 30, Issue:11

    Topics: Antidepressive Agents, Tricyclic; Behavior Therapy; Cognition; Depressive Disorder; Double-Blind Met

1982
The relationship of therapeutic response to antidepressant plasma levels: an update.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:11 Pt 2

    Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Biological Availability; Depressive

1982
The relationship of therapeutic response to antidepressant plasma levels: an update.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:11 Pt 2

    Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Biological Availability; Depressive

1982
Effects of doxepin on blood pressure and heart rate in patients with primary major affective disorder.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:6

    Topics: Adult; Aged; Blood Pressure; Depressive Disorder; Doxepin; Female; Heart Rate; Humans; Male; Middle

1982
Effects of doxepin on blood pressure and heart rate in patients with primary major affective disorder.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:6

    Topics: Adult; Aged; Blood Pressure; Depressive Disorder; Doxepin; Female; Heart Rate; Humans; Male; Middle

1982
Correct titration of non-drugs and some other methodological issues.
    Neuropsychobiology, 1994, Volume: 30, Issue:1

    Topics: Administration, Oral; Amitriptyline; Anxiety Disorders; Benperidol; Depressive Disorder; Dose-Respon

1994
Correct titration of non-drugs and some other methodological issues.
    Neuropsychobiology, 1994, Volume: 30, Issue:1

    Topics: Administration, Oral; Amitriptyline; Anxiety Disorders; Benperidol; Depressive Disorder; Dose-Respon

1994
Tricyclic-induced seizures and absent ECT response.
    The British journal of psychiatry : the journal of mental science, 1994, Volume: 164, Issue:3

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Electroconvulsive The

1994
Tricyclic-induced seizures and absent ECT response.
    The British journal of psychiatry : the journal of mental science, 1994, Volume: 164, Issue:3

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Electroconvulsive The

1994
Somatisation as a presentation in depression and post-traumatic stress disorder among Cambodian refugees.
    The Australian and New Zealand journal of psychiatry, 1993, Volume: 27, Issue:3

    Topics: Adult; Cambodia; Combined Modality Therapy; Depressive Disorder; Doxepin; Ethnicity; Female; Humans;

1993
Somatisation as a presentation in depression and post-traumatic stress disorder among Cambodian refugees.
    The Australian and New Zealand journal of psychiatry, 1993, Volume: 27, Issue:3

    Topics: Adult; Cambodia; Combined Modality Therapy; Depressive Disorder; Doxepin; Ethnicity; Female; Humans;

1993
Platelet serotonergic indices in major depression: up-regulation of 5-HT2A receptors unchanged by antidepressant treatment.
    Psychiatry research, 1997, Feb-07, Volume: 66, Issue:2-3

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Blood Platelets; Carrier Proteins; De

1997
Platelet serotonergic indices in major depression: up-regulation of 5-HT2A receptors unchanged by antidepressant treatment.
    Psychiatry research, 1997, Feb-07, Volume: 66, Issue:2-3

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Blood Platelets; Carrier Proteins; De

1997
[Current therapeutic possibilities with tricyclic antidepressive agents].
    Der Nervenarzt, 1994, Volume: 65, Issue:8 Suppl

    Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Humans

1994
[Current therapeutic possibilities with tricyclic antidepressive agents].
    Der Nervenarzt, 1994, Volume: 65, Issue:8 Suppl

    Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Humans

1994
A Markov process analysis comparing the cost effectiveness of maintenance therapy with citalopram versus standard therapy in major depression.
    PharmacoEconomics, 1995, Volume: 8, Issue:2

    Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Citalopram; Cost-Benefit Ana

1995
A Markov process analysis comparing the cost effectiveness of maintenance therapy with citalopram versus standard therapy in major depression.
    PharmacoEconomics, 1995, Volume: 8, Issue:2

    Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Citalopram; Cost-Benefit Ana

1995
Could you be blamed for a patient's suicide?
    Medical economics, 1999, Apr-26, Volume: 76, Issue:8

    Topics: Adult; Antidepressive Agents; Depressive Disorder; Doxepin; Drug Prescriptions; Family Practice; Fem

1999
Could you be blamed for a patient's suicide?
    Medical economics, 1999, Apr-26, Volume: 76, Issue:8

    Topics: Adult; Antidepressive Agents; Depressive Disorder; Doxepin; Drug Prescriptions; Family Practice; Fem

1999
[Depression of a developmentally retarded patient].
    Duodecim; laaketieteellinen aikakauskirja, 1996, Volume: 112, Issue:3

    Topics: Abnormalities, Multiple; Antidepressive Agents, Tricyclic; Depressive Disorder; Disease Progression;

1996
[Depression of a developmentally retarded patient].
    Duodecim; laaketieteellinen aikakauskirja, 1996, Volume: 112, Issue:3

    Topics: Abnormalities, Multiple; Antidepressive Agents, Tricyclic; Depressive Disorder; Disease Progression;

1996
'Everybody looks at my pubic bone'--a case report of an adolescent patient with body dysmorphic disorder.
    Acta psychiatrica Scandinavica, 2000, Volume: 101, Issue:1

    Topics: Adolescent; Antidepressive Agents, Tricyclic; Combined Modality Therapy; Comorbidity; Depressive Dis

2000
'Everybody looks at my pubic bone'--a case report of an adolescent patient with body dysmorphic disorder.
    Acta psychiatrica Scandinavica, 2000, Volume: 101, Issue:1

    Topics: Adolescent; Antidepressive Agents, Tricyclic; Combined Modality Therapy; Comorbidity; Depressive Dis

2000
Managing depression in outpatients.
    The New England journal of medicine, 2001, Apr-19, Volume: 344, Issue:16

    Topics: Alcoholism; Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Drug Approval; Humans

2001
Managing depression in outpatients.
    The New England journal of medicine, 2001, Apr-19, Volume: 344, Issue:16

    Topics: Alcoholism; Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Drug Approval; Humans

2001
Doxepin plasma concentrations: is there really a therapeutic range?
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:4

    Topics: Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Female; Germany; Health Knowle

2001
Doxepin plasma concentrations: is there really a therapeutic range?
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:4

    Topics: Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Female; Germany; Health Knowle

2001
[Tricyclic antidepressants as inhibitors of brain glutathione-S-transferase].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2001, Volume: 11, Issue:66

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Autopsy; Binding Sites; Brain; Clomipramine; Depres

2001
[Tricyclic antidepressants as inhibitors of brain glutathione-S-transferase].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2001, Volume: 11, Issue:66

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Autopsy; Binding Sites; Brain; Clomipramine; Depres

2001
The effect of fluoxetine in depression associated with multiple sclerosis.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1992, Volume: 37, Issue:2

    Topics: Adult; Cognition Disorders; Depressive Disorder; Doxepin; Female; Fluoxetine; Humans; Multiple Scler

1992
The effect of fluoxetine in depression associated with multiple sclerosis.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1992, Volume: 37, Issue:2

    Topics: Adult; Cognition Disorders; Depressive Disorder; Doxepin; Female; Fluoxetine; Humans; Multiple Scler

1992
Effects of carbamazepine on serum antidepressant concentrations in psychiatric patients.
    Journal of clinical psychopharmacology, 1991, Volume: 11, Issue:5

    Topics: Adult; Age Factors; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Carbamazepine; Depressiv

1991
Effects of carbamazepine on serum antidepressant concentrations in psychiatric patients.
    Journal of clinical psychopharmacology, 1991, Volume: 11, Issue:5

    Topics: Adult; Age Factors; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Carbamazepine; Depressiv

1991
Is doxepin a safer tricyclic for the heart?
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:8

    Topics: Aged; Arrhythmias, Cardiac; Blood Pressure; Depressive Disorder; Dose-Response Relationship, Drug; D

1991
Is doxepin a safer tricyclic for the heart?
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:8

    Topics: Aged; Arrhythmias, Cardiac; Blood Pressure; Depressive Disorder; Dose-Response Relationship, Drug; D

1991
Tricyclics and heart failure.
    The American journal of psychiatry, 1991, Volume: 148, Issue:11

    Topics: Aged; Depressive Disorder; Doxepin; Heart Failure; Humans; Male; Myocardial Contraction; Nortriptyli

1991
Tricyclics and heart failure.
    The American journal of psychiatry, 1991, Volume: 148, Issue:11

    Topics: Aged; Depressive Disorder; Doxepin; Heart Failure; Humans; Male; Myocardial Contraction; Nortriptyli

1991
Prediction of steady-state plasma levels of doxepin and imipramine from single dose levels in depressed outpatients.
    Journal of psychiatry & neuroscience : JPN, 1991, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Ambulatory Care; Depressive Disorder; Dose-Response Relationship, Drug; Doxepin;

1991
Prediction of steady-state plasma levels of doxepin and imipramine from single dose levels in depressed outpatients.
    Journal of psychiatry & neuroscience : JPN, 1991, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Ambulatory Care; Depressive Disorder; Dose-Response Relationship, Drug; Doxepin;

1991
Cis- and trans-isomers of doxepin and desmethyldoxepin in the plasma of depressed patients treated with doxepin.
    Therapeutic drug monitoring, 1990, Volume: 12, Issue:2

    Topics: Chromatography, Gas; Depressive Disorder; Doxepin; Humans; Stereoisomerism

1990
Cis- and trans-isomers of doxepin and desmethyldoxepin in the plasma of depressed patients treated with doxepin.
    Therapeutic drug monitoring, 1990, Volume: 12, Issue:2

    Topics: Chromatography, Gas; Depressive Disorder; Doxepin; Humans; Stereoisomerism

1990
Rhabdomyolysis in a depressed patient following overdose with combined drug therapy and alcohol.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:2

    Topics: Adult; Alcoholic Intoxication; Depressive Disorder; Diazepam; Doxepin; Fluoxetine; Humans; Male; Rha

1990
Rhabdomyolysis in a depressed patient following overdose with combined drug therapy and alcohol.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:2

    Topics: Adult; Alcoholic Intoxication; Depressive Disorder; Diazepam; Doxepin; Fluoxetine; Humans; Male; Rha

1990
Doxepin-induced cardiac dysrhythmia.
    Journal of clinical psychopharmacology, 1988, Volume: 8, Issue:2

    Topics: Adult; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Depressive Disorder; Doxepin; Female; Hea

1988
Doxepin-induced cardiac dysrhythmia.
    Journal of clinical psychopharmacology, 1988, Volume: 8, Issue:2

    Topics: Adult; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Depressive Disorder; Doxepin; Female; Hea

1988
Comparative plasma levels of doxepin and desipramine in the elderly.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1989, Volume: 34, Issue:9

    Topics: Administration, Oral; Aged; Aged, 80 and over; Depressive Disorder; Desipramine; Dose-Response Relat

1989
Comparative plasma levels of doxepin and desipramine in the elderly.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1989, Volume: 34, Issue:9

    Topics: Administration, Oral; Aged; Aged, 80 and over; Depressive Disorder; Desipramine; Dose-Response Relat

1989
Depression-dependent exacerbation of tardive dyskinesia.
    The British journal of psychiatry : the journal of mental science, 1989, Volume: 155

    Topics: Depressive Disorder; Doxepin; Dyskinesia, Drug-Induced; Electroconvulsive Therapy; Female; Follow-Up

1989
Depression-dependent exacerbation of tardive dyskinesia.
    The British journal of psychiatry : the journal of mental science, 1989, Volume: 155

    Topics: Depressive Disorder; Doxepin; Dyskinesia, Drug-Induced; Electroconvulsive Therapy; Female; Follow-Up

1989
Antidepressants and cessation of smoking.
    The American journal of psychiatry, 1989, Volume: 146, Issue:9

    Topics: Antidepressive Agents; Depressive Disorder; Doxepin; Humans; Smoking Prevention; Tobacco Use Disorde

1989
Antidepressants and cessation of smoking.
    The American journal of psychiatry, 1989, Volume: 146, Issue:9

    Topics: Antidepressive Agents; Depressive Disorder; Doxepin; Humans; Smoking Prevention; Tobacco Use Disorde

1989
A case of immune complex hemolytic anemia, thrombocytopenia, and acute renal failure associated with doxepin use.
    The Journal of clinical psychiatry, 1989, Volume: 50, Issue:3

    Topics: Acute Kidney Injury; Anemia, Hemolytic, Autoimmune; Depressive Disorder; Doxepin; Humans; Male; Midd

1989
A case of immune complex hemolytic anemia, thrombocytopenia, and acute renal failure associated with doxepin use.
    The Journal of clinical psychiatry, 1989, Volume: 50, Issue:3

    Topics: Acute Kidney Injury; Anemia, Hemolytic, Autoimmune; Depressive Disorder; Doxepin; Humans; Male; Midd

1989
[Psychopathologic prediction of ambulatory doxepin response. A replication trial].
    Der Nervenarzt, 1988, Volume: 59, Issue:8

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Depressive Disorder; Doxepin; Female; Humans; Male; Middle

1988
[Psychopathologic prediction of ambulatory doxepin response. A replication trial].
    Der Nervenarzt, 1988, Volume: 59, Issue:8

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Depressive Disorder; Doxepin; Female; Humans; Male; Middle

1988
A replication study for the prediction of doxepine-response in depressed outpatients.
    Pharmacopsychiatry, 1988, Volume: 21, Issue:6

    Topics: Depressive Disorder; Doxepin; Humans; Outpatients; Psychiatric Status Rating Scales

1988
A replication study for the prediction of doxepine-response in depressed outpatients.
    Pharmacopsychiatry, 1988, Volume: 21, Issue:6

    Topics: Depressive Disorder; Doxepin; Humans; Outpatients; Psychiatric Status Rating Scales

1988
The jitteriness syndrome in panic disorder patients treated with antidepressants.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:3

    Topics: Adult; Akathisia, Drug-Induced; Antidepressive Agents, Tricyclic; Anxiety Disorders; Depressive Diso

1988
The jitteriness syndrome in panic disorder patients treated with antidepressants.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:3

    Topics: Adult; Akathisia, Drug-Induced; Antidepressive Agents, Tricyclic; Anxiety Disorders; Depressive Diso

1988
Tricyclic antidepressant blood levels.
    American family physician, 1988, Volume: 37, Issue:3

    Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Female; Humans; Male

1988
Tricyclic antidepressant blood levels.
    American family physician, 1988, Volume: 37, Issue:3

    Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Female; Humans; Male

1988
Dystonic reactions to amitriptyline and doxepin.
    The American journal of psychiatry, 1988, Volume: 145, Issue:5

    Topics: Adult; Amitriptyline; Basal Ganglia Diseases; Depressive Disorder; Doxepin; Dystonia; Female; Humans

1988
Dystonic reactions to amitriptyline and doxepin.
    The American journal of psychiatry, 1988, Volume: 145, Issue:5

    Topics: Adult; Amitriptyline; Basal Ganglia Diseases; Depressive Disorder; Doxepin; Dystonia; Female; Humans

1988
Doxepin-cholestyramine interaction.
    Psychosomatics, 1988,Spring, Volume: 29, Issue:2

    Topics: Aged; Cholestyramine Resin; Depressive Disorder; Doxepin; Drug Interactions; Humans; Male

1988
Doxepin-cholestyramine interaction.
    Psychosomatics, 1988,Spring, Volume: 29, Issue:2

    Topics: Aged; Cholestyramine Resin; Depressive Disorder; Doxepin; Drug Interactions; Humans; Male

1988
Selected tricyclic antidepressants in the management of chronic benign pain.
    Southern medical journal, 1988, Volume: 81, Issue:5

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chronic Disease; Depressive Disorder; Doxepin; Huma

1988
Selected tricyclic antidepressants in the management of chronic benign pain.
    Southern medical journal, 1988, Volume: 81, Issue:5

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chronic Disease; Depressive Disorder; Doxepin; Huma

1988
Combined drug therapy for an elderly depressed patient.
    The American journal of psychiatry, 1988, Volume: 145, Issue:8

    Topics: Aged; Depressive Disorder; Doxepin; Drug Therapy, Combination; Female; Humans; Lithium; Phenelzine

1988
Combined drug therapy for an elderly depressed patient.
    The American journal of psychiatry, 1988, Volume: 145, Issue:8

    Topics: Aged; Depressive Disorder; Doxepin; Drug Therapy, Combination; Female; Humans; Lithium; Phenelzine

1988
Five to fifteen years' maintenance doxepin therapy.
    International clinical psychopharmacology, 1986, Volume: 1, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Depressive Disorder; Doxepin; Drug Interactions; Fe

1986
Five to fifteen years' maintenance doxepin therapy.
    International clinical psychopharmacology, 1986, Volume: 1, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Depressive Disorder; Doxepin; Drug Interactions; Fe

1986
Profound hypoglycemia with the addition of a tricyclic antidepressant to maintenance sulfonylurea therapy.
    The American journal of psychiatry, 1987, Volume: 144, Issue:9

    Topics: Aged; Chlorpropamide; Depressive Disorder; Diabetes Complications; Diabetes Mellitus; Doxepin; Drug

1987
Profound hypoglycemia with the addition of a tricyclic antidepressant to maintenance sulfonylurea therapy.
    The American journal of psychiatry, 1987, Volume: 144, Issue:9

    Topics: Aged; Chlorpropamide; Depressive Disorder; Diabetes Complications; Diabetes Mellitus; Doxepin; Drug

1987
Acupuncture and myofascial pain: treatment failure after administration of tricyclic antidepressants.
    Medical hypotheses, 1986, Volume: 19, Issue:4

    Topics: Acupuncture Therapy; Depressive Disorder; Doxepin; Endorphins; Female; Humans; Hyperalgesia; Middle

1986
Acupuncture and myofascial pain: treatment failure after administration of tricyclic antidepressants.
    Medical hypotheses, 1986, Volume: 19, Issue:4

    Topics: Acupuncture Therapy; Depressive Disorder; Doxepin; Endorphins; Female; Humans; Hyperalgesia; Middle

1986
Trazodone-induced mania.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:10

    Topics: Alcoholism; Bipolar Disorder; Depressive Disorder; Doxepin; Humans; Male; Middle Aged; Trazodone

1987
Trazodone-induced mania.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:10

    Topics: Alcoholism; Bipolar Disorder; Depressive Disorder; Doxepin; Humans; Male; Middle Aged; Trazodone

1987
Antidepressant treatment of medical-surgical inpatients by nonpsychiatric physicians.
    Archives of general psychiatry, 1987, Volume: 44, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents; Chronic Disease; Depressive Di

1987
Antidepressant treatment of medical-surgical inpatients by nonpsychiatric physicians.
    Archives of general psychiatry, 1987, Volume: 44, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents; Chronic Disease; Depressive Di

1987
Patient with chronic and apparently treatment-resistant dysthymia.
    The American journal of psychiatry, 1986, Volume: 143, Issue:2

    Topics: Adult; Amoxapine; Antidepressive Agents; Chronic Disease; Depressive Disorder; Doxepin; Humans; Male

1986
Patient with chronic and apparently treatment-resistant dysthymia.
    The American journal of psychiatry, 1986, Volume: 143, Issue:2

    Topics: Adult; Amoxapine; Antidepressive Agents; Chronic Disease; Depressive Disorder; Doxepin; Humans; Male

1986
Excretion of doxepin and N-desmethyldoxepin in human milk.
    British journal of clinical pharmacology, 1985, Volume: 20, Issue:5

    Topics: Adult; Breast Feeding; Depressive Disorder; Doxepin; Female; Humans; Infant; Milk, Human

1985
Excretion of doxepin and N-desmethyldoxepin in human milk.
    British journal of clinical pharmacology, 1985, Volume: 20, Issue:5

    Topics: Adult; Breast Feeding; Depressive Disorder; Doxepin; Female; Humans; Infant; Milk, Human

1985