doxepin has been researched along with Cicatrix in 2 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Cicatrix: The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effect of doxepin hydrochloride 5% cream on reducing pruritus in burn scar patients compared to a placebo cream." | 5.34 | Doxepin cream is not effective in reducing itch in burn scar patients: A multicenter triple-blind randomized clinical crossover trial. ( Breederveld, RS; Kwa, KAA; Legemate, CM; Meij-de Vries, A; Middelkoop, E; Nieuwenhuis, MK; Pijpe, A; van Baar, ME, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kwa, KAA | 1 |
| Legemate, CM | 1 |
| Pijpe, A | 1 |
| Meij-de Vries, A | 1 |
| Middelkoop, E | 1 |
| van Baar, ME | 1 |
| Breederveld, RS | 1 |
| Nieuwenhuis, MK | 1 |
| Queruel, P | 1 |
| Bartholomei, MN | 1 |
| Chauvineau-Mortelette, V | 1 |
| Cabaret, E | 1 |
| Bartoli, JL | 1 |
| Naville, L | 1 |
| Laveix, I | 1 |
| Arnaudo, L | 1 |
1 trial available for doxepin and Cicatrix
| Article | Year |
|---|---|
Doxepin cream is not effective in reducing itch in burn scar patients: A multicenter triple-blind randomized clinical crossover trial.
Topics: Administration, Cutaneous; Adult; Body Surface Area; Burns; Cicatrix; Cross-Over Studies; Double-Bli | 2020 |
1 other study available for doxepin and Cicatrix
| Article | Year |
|---|---|
Use of topical doxepin for the treatment of burn scar pruritus in adults: An inaccessible therapeutic alternative?
Topics: Administration, Cutaneous; Adult; Burns; Cicatrix; Doxepin; Drug Costs; France; Histamine Antagonist | 2020 |