doxepin and Chronic Kidney Failure studies

Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.

Research Excerpts

Excerpt	Relevance	Reference
"We suggest that doxepin, a tricyclic antidepressant with anti-H1 receptor effect, can help improve pruritus resistant to antihistamines in end-stage renal disease patients who undergo hemodialysis."	9.12	Low-dose doxepin for treatment of pruritus in patients on hemodialysis. ( Farrokhi, F; Firouzan, A; Nasli Esfahani, E; Nasrollahi, A; Pour-Reza-Gholi, F, 2007)
"We suggest that doxepin, a tricyclic antidepressant with anti-H1 receptor effect, can help improve pruritus resistant to antihistamines in end-stage renal disease patients who undergo hemodialysis."	5.12	Low-dose doxepin for treatment of pruritus in patients on hemodialysis. ( Farrokhi, F; Firouzan, A; Nasli Esfahani, E; Nasrollahi, A; Pour-Reza-Gholi, F, 2007)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

doxepin and Chronic Kidney Failure

Research Excerpts

Research

Studies (1)

Authors

Trials

Authors	Studies
Pour-Reza-Gholi, F	1
Nasrollahi, A	1
Firouzan, A	1
Nasli Esfahani, E	1
Farrokhi, F	1