doxepin has been researched along with Cardiac Complex, Premature in 4 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The doxepin patient was withdrawn from the study after 21 days of treatment when the PVC's became increasingly frequent." | 2.67 | A comparison of the cardiac safety and therapeutic efficacy of trimipramine versus doxepin in geriatric depressed patients. ( Amin, M; Dastoor, D; MacDonald, C; Mirmiran, J; Nair, NP; Phillips, R; Schwartz, G; Thavundayil, JX, 1993) |
| "Maprotiline was associated with decreased PVCs in patients with a "high" baseline rate, while doxepin was associated with increased PVCs in this group." | 2.65 | Comparative cardiac effects of maprotiline and doxepin in elderly depressed patients. ( Ahles, S; Gwirtsman, H; Halaris, A; Hill, MA; Schwarcz, G; Shah, P, 1984) |
| " The toxic arrhythmogenic effects of the tricyclic antidepressants can be measured by RET and are partly autonomic tone manipulation." | 1.26 | Cardiotoxicity of amitriptyline and doxepin. ( Aronow, WS; Tobis, JM, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tobis, JM | 1 |
| Aronow, WS | 1 |
| Ahles, S | 1 |
| Gwirtsman, H | 1 |
| Halaris, A | 1 |
| Shah, P | 1 |
| Schwarcz, G | 1 |
| Hill, MA | 1 |
| Nair, NP | 1 |
| Amin, M | 1 |
| Schwartz, G | 1 |
| Dastoor, D | 1 |
| Thavundayil, JX | 1 |
| Mirmiran, J | 1 |
| MacDonald, C | 1 |
| Phillips, R | 1 |
| Meador-Woodruff, JH | 1 |
| Majchrzak, MJ | 1 |
2 trials available for doxepin and Cardiac Complex, Premature
| Article | Year |
|---|---|
Comparative cardiac effects of maprotiline and doxepin in elderly depressed patients.
Topics: Aged; Angina Pectoris; Anthracenes; Blood Pressure; Cardiac Complexes, Premature; Clinical Trials as | 1984 |
A comparison of the cardiac safety and therapeutic efficacy of trimipramine versus doxepin in geriatric depressed patients.
Topics: Age Factors; Aged; Analysis of Variance; Blood Pressure; Cardiac Complexes, Premature; Cognition; De | 1993 |
2 other studies available for doxepin and Cardiac Complex, Premature
| Article | Year |
|---|---|
Cardiotoxicity of amitriptyline and doxepin.
Topics: Amitriptyline; Animals; Bicarbonates; Cardiac Complexes, Premature; Dogs; Doxepin; Heart; Physostigm | 1981 |
Doxepin-induced cardiac dysrhythmia.
Topics: Adult; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Depressive Disorder; Doxepin; Female; Hea | 1988 |