doxepin has been researched along with Burns in 4 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effect of doxepin hydrochloride 5% cream on reducing pruritus in burn scar patients compared to a placebo cream." | 5.34 | Doxepin cream is not effective in reducing itch in burn scar patients: A multicenter triple-blind randomized clinical crossover trial. ( Breederveld, RS; Kwa, KAA; Legemate, CM; Meij-de Vries, A; Middelkoop, E; Nieuwenhuis, MK; Pijpe, A; van Baar, ME, 2020) |
| "Because PTSD may become chronic and difficult to treat if unrecognized, early intervention is desirable." | 1.27 | Treatment of acute posttraumatic stress disorder with tricyclic antidepressants. ( Blake, DJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kwa, KAA | 1 |
| Legemate, CM | 1 |
| Pijpe, A | 1 |
| Meij-de Vries, A | 1 |
| Middelkoop, E | 1 |
| van Baar, ME | 1 |
| Breederveld, RS | 1 |
| Nieuwenhuis, MK | 1 |
| Queruel, P | 1 |
| Bartholomei, MN | 1 |
| Chauvineau-Mortelette, V | 1 |
| Cabaret, E | 1 |
| Bartoli, JL | 1 |
| Naville, L | 1 |
| Laveix, I | 1 |
| Arnaudo, L | 1 |
| Orłowski, T | 1 |
| Struzyna, J | 1 |
| Badowski, A | 1 |
| Daciewicz, Z | 1 |
| Blake, DJ | 1 |
1 trial available for doxepin and Burns
| Article | Year |
|---|---|
Doxepin cream is not effective in reducing itch in burn scar patients: A multicenter triple-blind randomized clinical crossover trial.
Topics: Administration, Cutaneous; Adult; Body Surface Area; Burns; Cicatrix; Cross-Over Studies; Double-Bli | 2020 |
3 other studies available for doxepin and Burns
| Article | Year |
|---|---|
Use of topical doxepin for the treatment of burn scar pruritus in adults: An inaccessible therapeutic alternative?
Topics: Administration, Cutaneous; Adult; Burns; Cicatrix; Doxepin; Drug Costs; France; Histamine Antagonist | 2020 |
[Use of sinequan during dressing change in burns].
Topics: Adolescent; Adult; Bandages; Burns; Doxepin; Female; Humans; Hypnotics and Sedatives; Male; Middle A | 1979 |
Treatment of acute posttraumatic stress disorder with tricyclic antidepressants.
Topics: Accidents, Occupational; Accidents, Traffic; Acute Disease; Adult; Antidepressive Agents, Tricyclic; | 1986 |