Page last updated: 2024-10-26

doxepin and Burns

doxepin has been researched along with Burns in 4 studies

Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.

Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effect of doxepin hydrochloride 5% cream on reducing pruritus in burn scar patients compared to a placebo cream."5.34Doxepin cream is not effective in reducing itch in burn scar patients: A multicenter triple-blind randomized clinical crossover trial. ( Breederveld, RS; Kwa, KAA; Legemate, CM; Meij-de Vries, A; Middelkoop, E; Nieuwenhuis, MK; Pijpe, A; van Baar, ME, 2020)
"Because PTSD may become chronic and difficult to treat if unrecognized, early intervention is desirable."1.27Treatment of acute posttraumatic stress disorder with tricyclic antidepressants. ( Blake, DJ, 1986)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Kwa, KAA1
Legemate, CM1
Pijpe, A1
Meij-de Vries, A1
Middelkoop, E1
van Baar, ME1
Breederveld, RS1
Nieuwenhuis, MK1
Queruel, P1
Bartholomei, MN1
Chauvineau-Mortelette, V1
Cabaret, E1
Bartoli, JL1
Naville, L1
Laveix, I1
Arnaudo, L1
Orłowski, T1
Struzyna, J1
Badowski, A1
Daciewicz, Z1
Blake, DJ1

Trials

1 trial available for doxepin and Burns

ArticleYear
Doxepin cream is not effective in reducing itch in burn scar patients: A multicenter triple-blind randomized clinical crossover trial.
    Burns : journal of the International Society for Burn Injuries, 2020, Volume: 46, Issue:2

    Topics: Administration, Cutaneous; Adult; Body Surface Area; Burns; Cicatrix; Cross-Over Studies; Double-Bli

2020

Other Studies

3 other studies available for doxepin and Burns

ArticleYear
Use of topical doxepin for the treatment of burn scar pruritus in adults: An inaccessible therapeutic alternative?
    Burns : journal of the International Society for Burn Injuries, 2020, Volume: 46, Issue:1

    Topics: Administration, Cutaneous; Adult; Burns; Cicatrix; Doxepin; Drug Costs; France; Histamine Antagonist

2020
[Use of sinequan during dressing change in burns].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1979, Dec-01, Volume: 32, Issue:23

    Topics: Adolescent; Adult; Bandages; Burns; Doxepin; Female; Humans; Hypnotics and Sedatives; Male; Middle A

1979
Treatment of acute posttraumatic stress disorder with tricyclic antidepressants.
    Southern medical journal, 1986, Volume: 79, Issue:2

    Topics: Accidents, Occupational; Accidents, Traffic; Acute Disease; Adult; Antidepressive Agents, Tricyclic;

1986