Page last updated: 2024-10-26

doxepin and Bipolar Disorder

doxepin has been researched along with Bipolar Disorder in 12 studies

Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's4 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nasrallah, HA1
Lyskowksi, J1
Schroeder, D1
Jefferson, JW1
Galynker, II1
Rosenthal, RN1
Perkel, C1
Shwartz, A1
Evidente, VG1
Caviness, JN1
Amin, MM1
Ban, TA1
Lehmann, HE1
Marcotte, E1
Ayd, FJ1
Warneke, L1
Leinonen, E1
Lillsunde, P1
Laukkanen, V1
Ylitalo, P1
Kaye, NS1
Lennhoff, M1
Ewert, EG1
Murphy, HB1

Trials

1 trial available for doxepin and Bipolar Disorder

ArticleYear
Doxepin and imipramine in the treatment of depression: a double-blind crossover clinical study with EKG recordings.
    Psychopharmacology bulletin, 1978, Volume: 14, Issue:1

    Topics: Adjustment Disorders; Adult; Bipolar Disorder; Clinical Trials as Topic; Depression; Double-Blind Me

1978

Other Studies

11 other studies available for doxepin and Bipolar Disorder

ArticleYear
TCA-induced mania: differences between switchers and nonswitchers.
    Biological psychiatry, 1982, Volume: 17, Issue:2

    Topics: Adult; Affective Disorders, Psychotic; Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic;

1982
Tamoxifen-associated reduction in tricyclic antidepressant levels in blood.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:3

    Topics: Aged; Bipolar Disorder; Doxepin; Drug Interactions; Female; Humans; Tamoxifen

1995
Doxepin withdrawal mania.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:3

    Topics: Bipolar Disorder; Doxepin; Drug Therapy, Combination; Female; Humans; Lithium; Lorazepam; Middle Age

1995
Focal cortical transient preceding myoclonus during lithium and tricyclic antidepressant therapy.
    Neurology, 1999, Jan-01, Volume: 52, Issue:1

    Topics: Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain Chemistry; Doxepin; Drug Therapy, Co

1999
Maintenance doxepin (sinequan) therapy for depressive illness.
    Diseases of the nervous system, 1975, Volume: 36, Issue:3

    Topics: Adult; Aged; Bipolar Disorder; Chemical and Drug Induced Liver Injury; Chronic Disease; Depression;

1975
A case of manic-depressive illness in childhood.
    Canadian Psychiatric Association journal, 1975, Volume: 20, Issue:3

    Topics: Adolescent; Age Factors; Alberta; Bipolar Disorder; Child; Chlorpromazine; Doxepin; Electroconvulsiv

1975
Effects of carbamazepine on serum antidepressant concentrations in psychiatric patients.
    Journal of clinical psychopharmacology, 1991, Volume: 11, Issue:5

    Topics: Adult; Age Factors; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Carbamazepine; Depressiv

1991
Doxepin for treatment of mania.
    The American journal of psychiatry, 1989, Volume: 146, Issue:6

    Topics: Bipolar Disorder; Doxepin; Female; Humans; Middle Aged

1989
Trazodone-induced mania.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:10

    Topics: Alcoholism; Bipolar Disorder; Depressive Disorder; Doxepin; Humans; Male; Middle Aged; Trazodone

1987
[Corticoid-induced psychovegetative disorders and their therapy using Sinquan].
    Therapie der Gegenwart, 1973, Volume: 112, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Bipolar Disorder; Doxepin; Female; Humans; Long-Term Care; Male; Mid

1973
Differences between mental disorders of French Canadians and British Canadians.
    Canadian Psychiatric Association journal, 1974, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Alcoholism; Bipolar Disorder; Canada; Chlordiazepoxide; Cranio

1974