doxepin has been researched along with Anxiety in 26 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-one patients with endoscopically proven active duodenal ulcers were studied in a double-blind randomized trial comparing doxepin hydrochloride (50 mg during the first week, and 100 mg thereafter, at bedtime) and cimetidine (1,200 mg/day in four divided doses)." | 9.05 | Doxepin and cimetidine in the treatment of duodenal ulcer: a double-blind comparative study. ( Shah, BK; Shrivastava, RK; Siegal, H, 1985) |
| "Fluoxetine was compared to doxepin in geriatric out-patients with major depressive illness." | 6.66 | Double-blind comparative trials of fluoxetine and doxepin in geriatric patients with major depressive disorder. ( Cohn, JB; Feighner, JP, 1985) |
| "Twenty-one patients with endoscopically proven active duodenal ulcers were studied in a double-blind randomized trial comparing doxepin hydrochloride (50 mg during the first week, and 100 mg thereafter, at bedtime) and cimetidine (1,200 mg/day in four divided doses)." | 5.05 | Doxepin and cimetidine in the treatment of duodenal ulcer: a double-blind comparative study. ( Shah, BK; Shrivastava, RK; Siegal, H, 1985) |
| "Trebenzomine, a new psychotropic drug, was compared with doxepin in the treatment of anxiety and depression." | 5.04 | Controlled comparison of trebenzomine with doxepin as an antidepressant-anxiolytic. ( Borgen, LA; Goodman, LI; Muniz, C; Pena-Ramos, A, 1979) |
| "The effects of doxepin on the circulation and its anxiety relieving properties were studied in 67 patients who were premedicated with this drug before surgical operations." | 5.04 | [Premedication with doxepin (author's transl)]. ( Manz, R; Welsch, C, 1975) |
| "Fluoxetine was compared to doxepin in geriatric out-patients with major depressive illness." | 2.66 | Double-blind comparative trials of fluoxetine and doxepin in geriatric patients with major depressive disorder. ( Cohn, JB; Feighner, JP, 1985) |
| "Diazepam treated patients improved significantly more early in the trial, according to a few measures." | 2.64 | Doxepin or diazepam for anxious and anxious-depressed outpatients? ( Fisher, S; Gambill, JD; Gardos, G; Haskell, DS; McNair, DM, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (88.46) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshizawa, M | 1 |
| Tashiro, M | 1 |
| Fukudo, S | 1 |
| Yanai, K | 1 |
| Utsumi, A | 1 |
| Kano, M | 1 |
| Karahasi, M | 1 |
| Endo, Y | 1 |
| Morisita, J | 1 |
| Sato, Y | 1 |
| Adachi, M | 1 |
| Itoh, M | 1 |
| Hongo, M | 1 |
| Meagher, LJ | 1 |
| McKay, D | 1 |
| Herkes, GK | 1 |
| Needham, M | 1 |
| Koval'chuk, VV | 1 |
| Persson, G | 3 |
| Pinder, RM | 1 |
| Brogden, RN | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Bianchi, GN | 1 |
| Fergusson, DM | 1 |
| Haskell, DS | 1 |
| Gambill, JD | 1 |
| Gardos, G | 1 |
| McNair, DM | 1 |
| Fisher, S | 1 |
| Pena-Ramos, A | 1 |
| Muniz, C | 1 |
| Goodman, LI | 1 |
| Borgen, LA | 1 |
| Orłowski, T | 1 |
| Gil, J | 1 |
| Badowski, A | 1 |
| Finnerty, RJ | 2 |
| Goldberg, HL | 2 |
| Rickels, K | 2 |
| Roth, N | 1 |
| Manz, R | 1 |
| Welsch, C | 1 |
| Planche, R | 1 |
| Gathier, MC | 1 |
| Lambert, J | 1 |
| Woody, GE | 1 |
| O'Brien, CP | 1 |
| Mendels, J | 1 |
| Schless, A | 1 |
| Spensley, J | 1 |
| Light, RW | 1 |
| Merrill, EJ | 1 |
| Despars, J | 1 |
| Gordon, GH | 1 |
| Mutalipassi, LR | 1 |
| Feighner, JP | 1 |
| Cohn, JB | 1 |
| Shrivastava, RK | 1 |
| Shah, BK | 1 |
| Siegal, H | 1 |
| Grof, P | 1 |
| Saxena, B | 1 |
| Cantor, R | 1 |
| Daigle, L | 1 |
| Hetherington, D | 1 |
| Haines, T | 1 |
| Pigott, PV | 1 |
| Hollister, LE | 1 |
| Cole, JO | 1 |
| d'Elia, G | 1 |
| von Knorring, L | 1 |
| Marcusson, J | 1 |
| Mattsson, B | 1 |
| Perris, C | 1 |
| Haslam, MT | 1 |
1 review available for doxepin and Anxiety
| Article | Year |
|---|---|
Doxepin up-to-date: a review of its pharmacological properties and therapeutic efficacy with particular reference to depression.
Topics: Alcoholism; Amitriptyline; Animals; Anxiety; Cardiovascular Diseases; Depression; Doxepin; Drug Inte | 1977 |
17 trials available for doxepin and Anxiety
| Article | Year |
|---|---|
[Pharmacologic correction of psycho-emotive disorders in the rehabilitation of patients after removal of brain tumors].
Topics: Adult; Alprazolam; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain Neoplas | 2007 |
The effect of mental state on EPI scores.
Topics: Adjustment Disorders; Anxiety; Anxiety Disorders; Clinical Trials as Topic; Double-Blind Method; Dox | 1977 |
Doxepin or diazepam for anxious and anxious-depressed outpatients?
Topics: Adolescent; Adult; Aged; Ambulatory Care; Anxiety; Body Weight; Clinical Trials as Topic; Depression | 1978 |
Controlled comparison of trebenzomine with doxepin as an antidepressant-anxiolytic.
Topics: Adult; Anxiety; Benzopyrans; Chromans; Clinical Trials as Topic; Depression; Double-Blind Method; Do | 1979 |
Doxepin versus imipramine in psychoneurotic depressed patients with sleep disturbance: a double-blind study.
Topics: Adjustment Disorders; Adult; Aged; Anxiety; Cognition; Double-Blind Method; Doxepin; Drug Evaluation | 1978 |
[Premedication with doxepin (author's transl)].
Topics: Adult; Aged; Anxiety; Central Venous Pressure; Clinical Trials as Topic; Doxepin; Drug Evaluation; H | 1975 |
Depression and anxiety in heroin addicts: a placebo-controlled study of doxepin in combination with methadone.
Topics: Administration, Oral; Adult; Alcoholic Intoxication; Amphetamine; Anxiety; Barbiturates; Capsules; C | 1975 |
A controlled comparison of doxepin h.s. and doxepin q.i.d.
Topics: Adult; Anxiety; Depression; Doxepin; Female; Humans; Male; Middle Aged; Placebos; Psychiatric Status | 1975 |
Doxepin treatment of depressed patients with chronic obstructive pulmonary disease.
Topics: Aged; Anxiety; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Doxepin; Emotions | 1986 |
Double-blind comparative trials of fluoxetine and doxepin in geriatric patients with major depressive disorder.
Topics: Age Factors; Aged; Anxiety; Blood Pressure; Body Weight; Clinical Trials as Topic; Depressive Disord | 1985 |
Doxepin and cimetidine in the treatment of duodenal ulcer: a double-blind comparative study.
Topics: Adult; Aged; Anxiety; Cimetidine; Clinical Trials as Topic; Depression; Double-Blind Method; Doxepin | 1985 |
Doxepin versus amitriptyline in depression: a sequential double-blind study.
Topics: Amitriptyline; Anxiety; Depression; Doxepin; Female; Humans; Hypochondriasis; Intellectual Disabilit | 1974 |
A review of clinical studies with combinations of fluphenazine and nortriptyline.
Topics: Amitriptyline; Anxiety; Central Nervous System; Clinical Trials as Topic; Depression; Diazepam; Doxe | 1972 |
Doxepin hydrochloride.
Topics: Alcoholism; Amitriptyline; Anxiety; Clinical Trials as Topic; Depression; Doxepin; Drug Evaluation; | 1974 |
Doxepin: is a single daily dose enough?
Topics: Administration, Oral; Adult; Anxiety; Clinical Trials as Topic; Depression; Doxepin; Drug Evaluation | 1974 |
A double blind comparison between doxepin and diazepam in the treatment of states of anxiety.
Topics: Adolescent; Adult; Aged; Anxiety; Body Weight; Clinical Trials as Topic; Depression; Diazepam; Doxep | 1974 |
A comparative trial of lorazepam and doxepin in the treatment of anxiety.
Topics: Administration, Oral; Anxiety; Benzodiazepinones; Doxepin; Humans; Statistics as Topic | 1974 |
8 other studies available for doxepin and Anxiety
| Article | Year |
|---|---|
Increased brain histamine H1 receptor binding in patients with anorexia nervosa.
Topics: Anorexia Nervosa; Antidepressive Agents, Tricyclic; Anxiety; Brain; Brain Chemistry; Data Interpreta | 2009 |
Parkinsonism-hyperpyrexia syndrome: the role of electroconvulsive therapy.
Topics: Acetaminophen; Acyclovir; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Anxiety Agents; Anti-Ba | 2006 |
Non-pharmacological factors in drug treatment of anxiety states.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Attitude to Health; Diazepam; Doxepin; Evalua | 1976 |
Factors related to drug compliance and attrition in neurotic outpatients treated with anxiolytics.
Topics: Adult; Age Factors; Anxiety; Attitude to Health; Diazepam; Double-Blind Method; Doxepin; Educational | 1979 |
[Use of sinequan as a premedication agent in endoscopic examinations].
Topics: Adult; Aged; Anxiety; Doxepin; Endoscopy; Female; Humans; Male; Middle Aged; Premedication | 1979 |
Fear of death in the aging.
Topics: Aged; Aging; Anxiety; Attitude to Death; Culture; Depression; Doxepin; Fear; Female; Humans; Male; M | 1978 |
[Description of a simple graphic model permitting the comparison of the course of depressive states].
Topics: Adjustment Disorders; Adult; Antidepressive Agents; Anxiety; Clomipramine; Depression; Doxepin; Fema | 1976 |
Doxepin: a useful adjunct in the treatment of heroin addicts in a methadone program.
Topics: Adult; Aged; Anxiety; California; Doxepin; Female; Heroin Dependence; Humans; Male; Methadone; Middl | 1976 |