doxepin has been researched along with Anxiety Disorders in 22 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Anxiety Disorders: Persistent and disabling ANXIETY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Doxepin and desipramine at final doses of 188 and 173 mg/day, respectively, were compared in 36 volunteers with major affective or dysthymic disorder and chronic back pain." | 9.05 | Antidepressants in concomitant chronic back pain and depression: doxepin and desipramine compared. ( Benedetti, C; Bokan, JA; Butler, S; Phillips, M; Spengler, D; Ward, N, 1984) |
| "A group of patients with both depression and chronic pain were treated with doxepin for 4 weeks." | 7.66 | Urinary 3-methoxy-4-hydroxyphenethylene glycol in the prediction of pain and depression relief with doxepin: preliminary findings. ( Bloom, VL; Fawcett, J; Friedel, RO; Ward, NG, 1983) |
| "Doxepin and desipramine at final doses of 188 and 173 mg/day, respectively, were compared in 36 volunteers with major affective or dysthymic disorder and chronic back pain." | 5.05 | Antidepressants in concomitant chronic back pain and depression: doxepin and desipramine compared. ( Benedetti, C; Bokan, JA; Butler, S; Phillips, M; Spengler, D; Ward, N, 1984) |
| "A group of patients with both depression and chronic pain were treated with doxepin for 4 weeks." | 3.66 | Urinary 3-methoxy-4-hydroxyphenethylene glycol in the prediction of pain and depression relief with doxepin: preliminary findings. ( Bloom, VL; Fawcett, J; Friedel, RO; Ward, NG, 1983) |
| "A study of 23 patients (16 females, 7 males), diagnosed as suffering from anxiety, was carried out using a flexible dosage regimen of doxepin." | 2.65 | Doxepin plasma levels and anxiolytic response. ( Bianchi, GN; Burrows, GD; Maguire, KP; Norman, TR; Wurm, JM, 1980) |
| "Doctors' prescription and dosing behaviour was investigated using data from 9 clinical trials in 550 patients treated with psychotropics." | 1.29 | Correct titration of non-drugs and some other methodological issues. ( Beneke, M; Fritze, J; Rasmus, W; Rød, IS, 1994) |
| "Desipramine was associated with a much higher frequency of jitteriness than was imipramine." | 1.27 | The jitteriness syndrome in panic disorder patients treated with antidepressants. ( Balon, R; Lycaki, H; Pohl, R; Yeragani, VK, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (81.82) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, M | 1 |
| Huang, F | 1 |
| Jiang, F | 1 |
| Mai, M | 1 |
| Guo, X | 1 |
| Zhang, Y | 1 |
| Xu, Y | 1 |
| Zu, H | 1 |
| Rademacher, S | 1 |
| Dietz, R | 1 |
| Haverkamp, W | 1 |
| Ward, NG | 2 |
| Bloom, VL | 2 |
| Dworkin, S | 1 |
| Fawcett, J | 2 |
| Narasimhachari, N | 1 |
| Friedel, RO | 2 |
| Ward, N | 1 |
| Bokan, JA | 1 |
| Phillips, M | 1 |
| Benedetti, C | 1 |
| Butler, S | 1 |
| Spengler, D | 1 |
| Schwab, JJ | 1 |
| Akiskal, HS | 1 |
| Arana, GW | 1 |
| Baldessarini, RJ | 1 |
| Barreira, PJ | 1 |
| Freinhar, J | 1 |
| Khan, MC | 1 |
| Bennie, EH | 1 |
| Stulemeijer, SM | 1 |
| Ravens, MA | 1 |
| Pishkin, V | 1 |
| Shurley, JT | 1 |
| Hekimian, LJ | 1 |
| Weise, CC | 1 |
| Friedhoff, AJ | 1 |
| Hertrich, O | 1 |
| Norman, TR | 1 |
| Burrows, GD | 1 |
| Bianchi, GN | 2 |
| Maguire, KP | 1 |
| Wurm, JM | 1 |
| Beneke, M | 1 |
| Rasmus, W | 1 |
| Rød, IS | 1 |
| Fritze, J | 1 |
| Fergusson, DM | 1 |
| Smith, JA | 1 |
| Renshaw, DC | 1 |
| Nutzinger, DO | 1 |
| Pohl, R | 1 |
| Yeragani, VK | 1 |
| Balon, R | 1 |
| Lycaki, H | 1 |
| Ciurezu, T | 1 |
| Timofte, G | 1 |
| Goldberg, HL | 1 |
| Finnerty, RJ | 1 |
| Nathan, L | 1 |
| Cole, JO | 1 |
| Downing, RW | 1 |
| Ciureza, T | 1 |
| Tudorache, D | 1 |
| Ionescu, R | 2 |
| Niţurad, A | 1 |
| Nica, S | 1 |
| Oproiu, L | 1 |
| Popovici, I | 1 |
| Roman, I | 1 |
| Curelaru, S | 1 |
9 trials available for doxepin and Anxiety Disorders
| Article | Year |
|---|---|
Clinical efficacy and safety of low-dose doxepin in Chinese patients with generalized anxiety disorder: A before-after study.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety Disorders; Blood Glucose; Body Weight; China; Choleste | 2022 |
Antidepressants in concomitant chronic back pain and depression: doxepin and desipramine compared.
Topics: Adult; Anxiety Disorders; Back Pain; beta-Endorphin; Chronic Disease; Clinical Trials as Topic; Depr | 1984 |
Mianserin and doxepin in the treatment of outpatient depression with anxiety.
Topics: Adult; Aged; Anxiety Disorders; Depressive Disorder; Dibenzazepines; Doxepin; Electrocardiography; F | 1983 |
Doxepin and hydroxyzine in treating anxiety: effects of failure and motivation on cognitive performance.
Topics: Adult; Anxiety Disorders; Cognition; Depressive Disorder; Doxepin; Humans; Hydroxyzine; Male; Middle | 1983 |
Onset of action of amoxapine and doxepin in outpatients with "mixed anxiety/depression".
Topics: Adult; Ambulatory Care; Amoxapine; Anxiety Disorders; Constipation; Depressive Disorder; Dibenzoxaze | 1983 |
Doxepin plasma levels and anxiolytic response.
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Doxepin; Female; Humans; Male; Middle Aged; Time | 1980 |
The effect of mental state on EPI scores.
Topics: Adjustment Disorders; Anxiety; Anxiety Disorders; Clinical Trials as Topic; Double-Blind Method; Dox | 1977 |
A clinical study of insomnia.
Topics: Adult; Aged; Anxiety Disorders; Clinical Trials as Topic; Depression; Doxepin; Drug Therapy, Combina | 1975 |
Doxepin in a single bedtime dose in psychoneurotic outpatients.
Topics: Adjustment Disorders; Administration, Oral; Adult; Ambulatory Care; Anxiety Disorders; Clinical Tria | 1974 |
13 other studies available for doxepin and Anxiety Disorders
| Article | Year |
|---|---|
QT prolongation and syncope with methadone, doxepin, and a beta-blocker.
Topics: Adrenergic beta-Antagonists; Adult; Anxiety Disorders; Doxepin; Electrocardiography; Humans; Long QT | 2005 |
Psychobiological markers in coexisting pain and depression: toward a unified theory.
Topics: Anxiety Disorders; Brain; Depressive Disorder; Doxepin; Humans; Hydroxyindoleacetic Acid; Methoxyhyd | 1982 |
Anxiety in depression.
Topics: Adult; Anxiety Disorders; Combined Modality Therapy; Depressive Disorder; Dose-Response Relationship | 1984 |
A clinical report of thymoleptic-responsive atypical paranoid psychoses.
Topics: Adult; Amitriptyline; Antidepressive Agents; Anxiety Disorders; Delusions; Diagnosis, Differential; | 1983 |
Doxepin's cardiotoxicity reviewed.
Topics: Animals; Anxiety Disorders; Cardiovascular Diseases; Depressive Disorder; Doxepin; Humans; Research | 1984 |
Urinary 3-methoxy-4-hydroxyphenethylene glycol in the prediction of pain and depression relief with doxepin: preliminary findings.
Topics: Adult; Anxiety Disorders; Depressive Disorder; Doxepin; Female; Glycols; Humans; Male; Methoxyhydrox | 1983 |
[Ataractic treatment in psychiatry and general medicine. Review of drugs. 5].
Topics: Acridines; Anxiety Disorders; Dementia; Depression; Doxepin; Humans; Mental Disorders; Mood Disorder | 1983 |
Correct titration of non-drugs and some other methodological issues.
Topics: Administration, Oral; Amitriptyline; Anxiety Disorders; Benperidol; Depressive Disorder; Dose-Respon | 1994 |
[Psychosocial and clinical predictors of the disease course in patients with cardiac phobia and panic attacks].
Topics: Anxiety Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Desensitization, Psychol | 1990 |
The jitteriness syndrome in panic disorder patients treated with antidepressants.
Topics: Adult; Akathisia, Drug-Induced; Antidepressive Agents, Tricyclic; Anxiety Disorders; Depressive Diso | 1988 |
Doxepine therapy in outpatients with depressive anxious states.
Topics: Adjustment Disorders; Adult; Anxiety Disorders; Doxepin; Female; Humans; Male; Mental Disorders; Mid | 1974 |
Mixed anxiety-depression. Fact or myth?
Topics: Adult; Amitriptyline; Anxiety Disorders; Barbiturates; Chlordiazepoxide; Depression; Doxepin; Female | 1974 |
Doxepin in the inpatient treatment of depressive states.
Topics: Adjustment Disorders; Adult; Aged; Alcoholism; Anxiety Disorders; Depression; Doxepin; Drug Evaluati | 1974 |