Page last updated: 2024-10-26

doxepin and Aging

doxepin has been researched along with Aging in 5 studies

Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" For clinical studies, molecular imaging technique such as positron emission tomography (PET), with ligands such as [11C]doxepin and [11C]pyrilamine, has been a useful tool."8.84[Molecular imaging of histamine receptors in the human brain]. ( Tashiro, M; Yanai, K, 2007)
" For clinical studies, molecular imaging technique such as positron emission tomography (PET), with ligands such as [11C]doxepin and [11C]pyrilamine, has been a useful tool."4.84[Molecular imaging of histamine receptors in the human brain]. ( Tashiro, M; Yanai, K, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tashiro, M1
Yanai, K2
Rao, ML1
Deister, A1
Laux, G1
Staberock, U1
Höflich, G1
Möller, HJ1
Schiffman, SS1
Graham, BG1
Suggs, MS1
Sattely-Miller, EA1
Higuchi, M1
Okamura, N1
Meguro, K1
Arai, H1
Itoh, M1
Iwata, R1
Ido, T1
Watanabe, T1
Sasaki, H1
Roth, N1

Reviews

1 review available for doxepin and Aging

ArticleYear
[Molecular imaging of histamine receptors in the human brain].
    Brain and nerve = Shinkei kenkyu no shinpo, 2007, Volume: 59, Issue:3

    Topics: Aging; Animals; Arousal; Blood-Brain Barrier; Brain; Brain Diseases; Carbon Radioisotopes; Cognition

2007

Trials

1 trial available for doxepin and Aging

ArticleYear
Low serum levels of tricyclic antidepressants in amitriptyline- and doxepin-treated inpatients with depressive syndromes are associated with nonresponse.
    Pharmacopsychiatry, 1996, Volume: 29, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Amitriptyline; Antidepressive Agents, Tricyclic; Body Mass In

1996

Other Studies

3 other studies available for doxepin and Aging

ArticleYear
Effect of psychotropic drugs on taste responses in young and elderly persons.
    Annals of the New York Academy of Sciences, 1998, Nov-30, Volume: 855

    Topics: Adult; Aged; Aging; Amitriptyline; Clomipramine; Desipramine; Doxepin; Female; Humans; Imipramine; M

1998
Histamine H(1) receptors in patients with Alzheimer's disease assessed by positron emission tomography.
    Neuroscience, 2000, Volume: 99, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain Chemistry; Carbon Radioisotopes; Cer

2000
Fear of death in the aging.
    American journal of psychotherapy, 1978, Volume: 32, Issue:4

    Topics: Aged; Aging; Anxiety; Attitude to Death; Culture; Depression; Doxepin; Fear; Female; Humans; Male; M

1978