doxepin has been researched along with Affective Disorders in 4 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A high proportion of affective disorders has been found among opioid-dependent patients; these are responsive to psychotherapy and to antidepressant treatment with doxepin." | 3.67 | Psychiatric disorders in opioid-dependent patients. ( McLellan, AT; O'Brien, CP; Woody, GE, 1984) |
| "In the treatment of depressive disorders the onset of action can be accelerated if the antidepressant drug is initially administered by intravenous infusion." | 2.68 | On the problems of switching from intravenous to oral administration in drug treatment of endogenous depression--a placebo-controlled double-blind trial with doxepin. ( Adler, L; Böke, J; Hajak, G; Hoffmann, G; Huether, G; Issinger, J; Kunert, HJ; Lehmann, K; Rüther, E, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koval'chuk, VV | 1 |
| O'Brien, CP | 1 |
| Woody, GE | 1 |
| McLellan, AT | 1 |
| Hertrich, O | 1 |
| Adler, L | 1 |
| Hajak, G | 1 |
| Lehmann, K | 1 |
| Kunert, HJ | 1 |
| Hoffmann, G | 1 |
| Issinger, J | 1 |
| Böke, J | 1 |
| Huether, G | 1 |
| Rüther, E | 1 |
2 trials available for doxepin and Affective Disorders
| Article | Year |
|---|---|
[Pharmacologic correction of psycho-emotive disorders in the rehabilitation of patients after removal of brain tumors].
Topics: Adult; Alprazolam; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain Neoplas | 2007 |
On the problems of switching from intravenous to oral administration in drug treatment of endogenous depression--a placebo-controlled double-blind trial with doxepin.
Topics: Administration, Oral; Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Met | 1997 |
2 other studies available for doxepin and Affective Disorders
| Article | Year |
|---|---|
Psychiatric disorders in opioid-dependent patients.
Topics: Counseling; Doxepin; Humans; Interview, Psychological; Mental Disorders; Mood Disorders; Opioid-Rela | 1984 |
[Ataractic treatment in psychiatry and general medicine. Review of drugs. 5].
Topics: Acridines; Anxiety Disorders; Dementia; Depression; Doxepin; Humans; Mental Disorders; Mood Disorder | 1983 |