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doxepin and Acute Kidney Failure

doxepin has been researched along with Acute Kidney Failure in 4 studies

Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.

Research Excerpts

ExcerptRelevanceReference
"Hypothermia (instead of the expected hyperthermia) is described for the first time as a persistent symptom during the course of a combined moclobemide-doxepin intoxication in an attempted suicide of a 16-year-old adolescent."7.76Hypothermia in a combined intoxication with doxepin and moclobemide in an adolescent. ( Armbrust, S; Bielstein, A; Franzelius, C; Kramer, HH; Nikischin, W; Rochholz, G, 2010)
"A 46-year-old man suffering from neurotic depression complicated by alcohol and benzodiazepine dependence developed Coombs'-positive hemolytic anemia and thrombocytopenia with acute renal failure after 5 weeks of monotherapy with doxepin at a final dosage of 100 mg daily."7.67A case of immune complex hemolytic anemia, thrombocytopenia, and acute renal failure associated with doxepin use. ( Conradty, M; Grohmann, R; Londong, V; Rüther, E; Witzgall, H; Wolf, B, 1989)
"A 50-year-old woman developed rhabdomyolysis and myoglobinuric renal impairment after an oral dose of 250 mg nitrazepam and 1,250 mg doxepin."7.67Rhabdomyolysis and acute renal failure following an overdose of doxepine and nitrazepam. ( Andersen, PT; Højgaard, AD; Møller-Petersen, J, 1988)
"Hypothermia (instead of the expected hyperthermia) is described for the first time as a persistent symptom during the course of a combined moclobemide-doxepin intoxication in an attempted suicide of a 16-year-old adolescent."3.76Hypothermia in a combined intoxication with doxepin and moclobemide in an adolescent. ( Armbrust, S; Bielstein, A; Franzelius, C; Kramer, HH; Nikischin, W; Rochholz, G, 2010)
"A 46-year-old man suffering from neurotic depression complicated by alcohol and benzodiazepine dependence developed Coombs'-positive hemolytic anemia and thrombocytopenia with acute renal failure after 5 weeks of monotherapy with doxepin at a final dosage of 100 mg daily."3.67A case of immune complex hemolytic anemia, thrombocytopenia, and acute renal failure associated with doxepin use. ( Conradty, M; Grohmann, R; Londong, V; Rüther, E; Witzgall, H; Wolf, B, 1989)
"A 50-year-old woman developed rhabdomyolysis and myoglobinuric renal impairment after an oral dose of 250 mg nitrazepam and 1,250 mg doxepin."3.67Rhabdomyolysis and acute renal failure following an overdose of doxepine and nitrazepam. ( Andersen, PT; Højgaard, AD; Møller-Petersen, J, 1988)
"During hospitalization he developed acute renal failure secondary to acute tubular necrosis."2.43Nephrogenic fibrosing dermopathy in a patient with acute renal failure never requiring dialysis. ( Callen, JP; Cassis, TB; Jackson, JM; Sonnier, GB, 2006)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Armbrust, S1
Nikischin, W1
Rochholz, G1
Franzelius, C1
Bielstein, A1
Kramer, HH1
Cassis, TB1
Jackson, JM1
Sonnier, GB1
Callen, JP1
Wolf, B1
Conradty, M1
Grohmann, R1
Rüther, E1
Witzgall, H1
Londong, V1
Højgaard, AD1
Andersen, PT1
Møller-Petersen, J1

Reviews

1 review available for doxepin and Acute Kidney Failure

ArticleYear
Nephrogenic fibrosing dermopathy in a patient with acute renal failure never requiring dialysis.
    International journal of dermatology, 2006, Volume: 45, Issue:1

    Topics: Acute Kidney Injury; Aged; Biopsy, Needle; Doxepin; Fibrosis; Follow-Up Studies; Humans; Immunohisto

2006

Other Studies

3 other studies available for doxepin and Acute Kidney Failure

ArticleYear
Hypothermia in a combined intoxication with doxepin and moclobemide in an adolescent.
    Forensic science international, 2010, Feb-25, Volume: 195, Issue:1-3

    Topics: Acute Kidney Injury; Adolescent; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Coma; Dox

2010
A case of immune complex hemolytic anemia, thrombocytopenia, and acute renal failure associated with doxepin use.
    The Journal of clinical psychiatry, 1989, Volume: 50, Issue:3

    Topics: Acute Kidney Injury; Anemia, Hemolytic, Autoimmune; Depressive Disorder; Doxepin; Humans; Male; Midd

1989
Rhabdomyolysis and acute renal failure following an overdose of doxepine and nitrazepam.
    Acta medica Scandinavica, 1988, Volume: 223, Issue:1

    Topics: Acute Kidney Injury; Creatine Kinase; Creatinine; Doxepin; Female; Humans; Middle Aged; Myoglobin; N

1988