Page last updated: 2024-10-26

doxazosin and Ureteral Calculi

doxazosin has been researched along with Ureteral Calculi in 15 studies

Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.

Ureteral Calculi: Stones in the URETER that are formed in the KIDNEY. They are rarely more than 5 mm in diameter for larger renal stones cannot enter ureters. They are often lodged at the ureteral narrowing and can cause excruciating renal colic.

Research Excerpts

ExcerptRelevanceReference
"Doxazosin dose was approximately 0."2.74Effectiveness of doxazosin in treatment of distal ureteral stones in children. ( Aydogdu, O; Burgu, B; Gucuk, A; Soygur, T; Suer, E, 2009)
"Doxazosin treatment proved to be safe and effective for distal-ureteral stones, as determined by earlier expulsion, decreased colic frequency, and absence of side effects."2.73Doxazosin for the management of distal-ureteral stones. ( Assimakopoulos, K; Athanasopoulos, A; Constantinides, C; Kallidonis, P; Katsakiori, PF; Liatsikos, EN; Perimenis, P; Stolzenburg, JU; Voudoukis, T, 2007)
" Although doxazosin resulted in significantly more adverse effects compared with the placebo, the patient's symptoms were mild and no further medical interventions were required."2.72The safety and efficacy of doxazosin in medical expulsion therapy for distal ureteric calculi: A meta-analysis. ( Cao, H; Cao, P; Gao, Z; Sun, Z; Wang, W; Yu, B; Zhang, F; Zhang, J; Zheng, X, 2021)
" Meanwhile the number of pain episodes, analgesic dosage and the number of days for spontaneous passage of the calculi through the ureter were also recorded."2.71The comparison and efficacy of 3 different alpha1-adrenergic blockers for distal ureteral stones. ( Basar, H; Basar, MM; Batislam, E; Ferhat, M; Tuglu, D; Yilmaz, E, 2005)
" The outcome measures were stone expulsive rate (SER), stone expulsive time (SET), pain episodes, analgesics consumption, and adverse events."2.66Efficacy and Safety of Doxazosin in Medical Expulsive Therapy for Distal Ureteral Stones: A Systematic Review and Meta-analysis. ( Ma, L; Wang, F; Yang, L; Zou, S, 2020)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.67)18.2507
2000's3 (20.00)29.6817
2010's8 (53.33)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Ma, L1
Zou, S1
Yang, L1
Wang, F1
Oestreich, MC1
Vernooij, RW1
Sathianathen, NJ1
Hwang, EC1
Kuntz, GM1
Koziarz, A1
Scales, CD1
Dahm, P1
Yu, B1
Zheng, X1
Sun, Z1
Cao, P1
Zhang, J1
Gao, Z1
Cao, H1
Zhang, F1
Wang, W1
Çelik, S1
Akdeniz, F1
Afsar Yildirim, M1
Bozkurt, O1
Gursoy Bulut, M1
Hacihasanoglu, ML1
Demir, O1
Erturhan, S3
Bayrak, O3
Sarica, K3
Prakash, J1
Singh, V1
Sharma, P1
Sen, H2
Sadioglu, E1
Seckiner, İ2
Aydogdu, O1
Burgu, B1
Gucuk, A1
Suer, E1
Soygur, T1
Zehri, AA1
Ather, MH1
Abbas, F1
Biyabani, SR1
Resorlu, B1
Bozkurt, OF1
Senocak, C1
Unsal, A1
Ateş, F1
Eryıldırım, B1
Öztürk, MI1
Turan, T1
Gürbüz, C1
Ekinci, MO1
Yıldırım, A1
Göktaş, C1
Şenkul, T1
Baturu, M1
Yilmaz, E1
Batislam, E1
Basar, MM1
Tuglu, D1
Ferhat, M1
Basar, H1
Liatsikos, EN1
Katsakiori, PF1
Assimakopoulos, K1
Voudoukis, T1
Kallidonis, P1
Constantinides, C1
Athanasopoulos, A1
Stolzenburg, JU1
Perimenis, P1
Ukhal', MI1
Malomuzh, OI1
Strashnyĭ, VV1
Shumilin, MV1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Use of Tamsulosin in Treatment of (10-15 mm) Lower Ureteric Stones in Adults With Non-emergent Symptoms: A Prospective Randomized Study[NCT03274700]Early Phase 180 participants (Anticipated)Interventional2017-10-01Not yet recruiting
[NCT00451061]Phase 4120 participants (Anticipated)Interventional2007-04-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for doxazosin and Ureteral Calculi

ArticleYear
Efficacy and Safety of Doxazosin in Medical Expulsive Therapy for Distal Ureteral Stones: A Systematic Review and Meta-analysis.
    Urology journal, 2020, 08-25, Volume: 17, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Doxazosin; Humans; Treatment Outcome; Ureteral Calculi

2020
Alpha-blockers after shock wave lithotripsy for renal or ureteral stones in adults.
    The Cochrane database of systematic reviews, 2020, 11-12, Volume: 11

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Chemotherapy, Adjuvant; Combined Modality Therapy; D

2020
The safety and efficacy of doxazosin in medical expulsion therapy for distal ureteric calculi: A meta-analysis.
    PloS one, 2021, Volume: 16, Issue:1

    Topics: Doxazosin; Humans; Randomized Controlled Trials as Topic; Safety; Ureteral Calculi

2021

Trials

8 trials available for doxazosin and Ureteral Calculi

ArticleYear
A comparison of efficacy of doxazosin 4 and 8 mg in medical expulsive therapy of distal ureteral stones: a prospective randomized clinical trial.
    Urolithiasis, 2017, Volume: 45, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Analgesics; Diclofenac; Dose-Response Relationship,

2017
Effectiveness of doxazosin in treatment of distal ureteral stones in children.
    The Journal of urology, 2009, Volume: 182, Issue:6

    Topics: Adolescent; Adrenergic alpha-Antagonists; Child; Child, Preschool; Doxazosin; Female; Humans; Male;

2009
Preliminary study of efficacy of doxazosin as a medical expulsive therapy of distal ureteric stones in a randomized clinical trial.
    Urology, 2010, Volume: 75, Issue:6

    Topics: Adult; Chi-Square Distribution; Diclofenac; Dose-Response Relationship, Drug; Doxazosin; Drug Admini

2010
Does the use of doxazosin influence the success of SWL in the treatment of upper ureteral stones? A multicenter, prospective and randomized study.
    Urological research, 2012, Volume: 40, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Doxazosin; Female; Humans; Lithotripsy; Male; Middle

2012
Efficacy of medical expulsive treatment with doxazosin in pediatric patients.
    Urology, 2013, Volume: 81, Issue:3

    Topics: Adolescent; Adrenergic alpha-1 Receptor Antagonists; Child; Child, Preschool; Doxazosin; Female; Hum

2013
The comparison and efficacy of 3 different alpha1-adrenergic blockers for distal ureteral stones.
    The Journal of urology, 2005, Volume: 173, Issue:6

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Doxazosin; Female; Hum

2005
The comparison and efficacy of 3 different alpha1-adrenergic blockers for distal ureteral stones.
    The Journal of urology, 2005, Volume: 173, Issue:6

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Doxazosin; Female; Hum

2005
The comparison and efficacy of 3 different alpha1-adrenergic blockers for distal ureteral stones.
    The Journal of urology, 2005, Volume: 173, Issue:6

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Doxazosin; Female; Hum

2005
The comparison and efficacy of 3 different alpha1-adrenergic blockers for distal ureteral stones.
    The Journal of urology, 2005, Volume: 173, Issue:6

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Doxazosin; Female; Hum

2005
Doxazosin for the management of distal-ureteral stones.
    Journal of endourology, 2007, Volume: 21, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adult; Colic; Doxazosin; Female; Humans; Male; Middle Aged; Models, St

2007
[The use of the alpha 1-adrenoblocker doxazosin in the pharmacotherapy of disorders of urine outflow of spastic origin].
    Likars'ka sprava, 1998, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Delayed-Action Preparations; Doxazosin; Humans; Male; Midd

1998

Other Studies

4 other studies available for doxazosin and Ureteral Calculi

ArticleYear
Tadalafil versus alpha blockers (alfuzosin, doxazosin, tamsulosin and silodosin) as medical expulsive therapy for < 10 mm distal and proximal ureteral stones.
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2018, Jun-30, Volume: 90, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Doxazosin; Female; Flank Pain; Humans;

2018
Reply by the authors.
    Urology, 2013, Volume: 81, Issue:6

    Topics: Adrenergic alpha-1 Receptor Antagonists; Doxazosin; Female; Humans; Male; Ureteral Calculi

2013
Re: Erturhan et al.: Efficacy of medical expulsive treatment with doxazosin in pediatric patients (Urology 2013;81:640-643).
    Urology, 2013, Volume: 81, Issue:6

    Topics: Adrenergic alpha-1 Receptor Antagonists; Doxazosin; Female; Humans; Male; Ureteral Calculi

2013
Effectiveness of doxazosin in the management of lower ureteral stones in male and female patients.
    International urology and nephrology, 2011, Volume: 43, Issue:3

    Topics: Adolescent; Adrenergic alpha-1 Receptor Antagonists; Adult; Anti-Inflammatory Agents, Non-Steroidal;

2011