doxazosin has been researched along with Rhinitis, Allergic in 1 studies
Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
Rhinitis, Allergic: An inflammation of the NASAL MUCOSA triggered by ALLERGENS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined the paradoxical hypothesis that the alpha-receptor inverse agonist doxazosin might produce beneficial effects in allergic rhinitis." | 9.22 | Effects of the inverse alpha-agonist doxazosin in allergic rhinitis. ( Lipworth, BJ; Manoharan, A; Morrison, AE, 2016) |
| "We examined the paradoxical hypothesis that the alpha-receptor inverse agonist doxazosin might produce beneficial effects in allergic rhinitis." | 5.22 | Effects of the inverse alpha-agonist doxazosin in allergic rhinitis. ( Lipworth, BJ; Manoharan, A; Morrison, AE, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Manoharan, A | 1 |
| Morrison, AE | 1 |
| Lipworth, BJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Proof of Concept Study in Allergic Rhinitis, to Evaluate the Differential Effects Between Single and Chronic Dosing of Doxazosin on Nasal Airway Calibre[NCT01946035] | Phase 4 | 17 participants (Actual) | Interventional | 2013-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for doxazosin and Rhinitis, Allergic
| Article | Year |
|---|---|
Effects of the inverse alpha-agonist doxazosin in allergic rhinitis.
Topics: Adrenergic alpha-1 Receptor Antagonists; Biomarkers; Doxazosin; Female; Humans; Male; Nasal Provocat | 2016 |