Page last updated: 2024-10-26

doxazosin and Prostatism

doxazosin has been researched along with Prostatism in 8 studies

Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.

Prostatism: Lower urinary tract symptom, such as slow urinary stream, associated with PROSTATIC HYPERPLASIA in older men.

Research Excerpts

ExcerptRelevanceReference
"Both doxazosin and terazosin were significantly more likely than finasteride to improve peak urine flow and nocturia, versus finasteride."6.46Finasteride for benign prostatic hyperplasia. ( Fink, HA; Macdonald, R; Rutks, I; Tacklind, J; Wilt, TJ, 2010)
"Doxazosin was given for 30 days, and at the second visit IPSS, NIH-CPSI and IIEF-5 scores, Qmax and PMR were once more analysed."5.37Effectiveness of doxazosin on erectile dysfunction in patients with lower urinary tract symptoms. ( Aktas, A; Eryildirim, B; Faydaci, G; Kuyumcuoglu, U; Tarhan, F; Tuncer, M, 2011)
"Both doxazosin and terazosin were significantly more likely than finasteride to improve peak urine flow and nocturia, versus finasteride."2.46Finasteride for benign prostatic hyperplasia. ( Fink, HA; Macdonald, R; Rutks, I; Tacklind, J; Wilt, TJ, 2010)
"Doxazosin was given for 30 days, and at the second visit IPSS, NIH-CPSI and IIEF-5 scores, Qmax and PMR were once more analysed."1.37Effectiveness of doxazosin on erectile dysfunction in patients with lower urinary tract symptoms. ( Aktas, A; Eryildirim, B; Faydaci, G; Kuyumcuoglu, U; Tarhan, F; Tuncer, M, 2011)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's7 (87.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barkin, J1
Diles, D1
Franks, B1
Berner, T1
Fusco, F1
Palmieri, A1
Ficarra, V1
Giannarini, G1
Novara, G1
Longo, N1
Verze, P1
Creta, M1
Mirone, V1
Liu, Q1
Zhu, Y1
Liu, J1
Qi, J1
Kang, J1
Kaplan, SA1
Lavallée, LT1
Dahm, P1
Breau, RH1
Tacklind, J1
Fink, HA1
Macdonald, R1
Rutks, I1
Wilt, TJ1
Faydaci, G1
Kuyumcuoglu, U1
Eryildirim, B1
Aktas, A1
Tarhan, F1
Tuncer, M1
Liao, CH1
Lin, VC1
Chung, SD1
Kuo, HC1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prophylactic Tamsulosin in Prevention of Post-operative Urinary Retention in Men After Transanal Endoscopic Microsurgery: A Multicenter Randomized, Double-blind, Placebo-controlled Clinical Trial[NCT03314025]Phase 2158 participants (Anticipated)Interventional2017-10-06Recruiting
The Effect of Traditional Chinese Medicine VGH-BPH1 on Patients With Benign Prostatic Hyperplasia: A Double-blinded Randomized Placebo-controlled Cross-over Study[NCT03829904]Phase 1/Phase 223 participants (Actual)Interventional2019-03-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for doxazosin and Prostatism

ArticleYear
α1-Blockers Improve Benign Prostatic Obstruction in Men with Lower Urinary Tract Symptoms: A Systematic Review and Meta-analysis of Urodynamic Studies.
    European urology, 2016, Volume: 69, Issue:6

    Topics: Adrenergic alpha-1 Receptor Antagonists; Clinical Trials as Topic; Doxazosin; Humans; Indoles; Male;

2016
Current role of alpha-blockers in the treatment of benign prostatic hyperplasia.
    BJU international, 2008, Volume: 102 Suppl 2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Clinical Trials as Topic; Doxazosin; Drug Administration

2008
Finasteride for benign prostatic hyperplasia.
    The Cochrane database of systematic reviews, 2010, Oct-06, Issue:10

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Disease Progression; Doxazosin; Drug The

2010

Other Studies

5 other studies available for doxazosin and Prostatism

ArticleYear
Alpha blocker monotherapy versus combination therapy with antimuscarinics in men with persistent LUTS refractory to alpha-adrenergic treatment: patterns of persistence.
    The Canadian journal of urology, 2015, Volume: 22, Issue:4

    Topics: Administrative Claims, Healthcare; Adrenergic alpha-Antagonists; Aged; Benzofurans; Doxazosin; Drug

2015
Ultrasound image features of intravesical prostatic protrusion indicated failure of medication therapy of finasteride and doxazosin in patients with benign prostatic hyperplasia (LUTS/BPH).
    International urology and nephrology, 2017, Volume: 49, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Doxazosin; Drug Therapy, Combination; Finasteride; Hu

2017
Evidence-based urology in practice: composite endpoints.
    BJU international, 2010, Volume: 106, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Doxazosin; Drug Therapy, Combination; Endpoint Determination; Evidence

2010
Effectiveness of doxazosin on erectile dysfunction in patients with lower urinary tract symptoms.
    International urology and nephrology, 2011, Volume: 43, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Doxazosin; Erectile Dysfunction; Humans; Male; Middle Aged;

2011
Therapeutic effect of α-blockers and antimuscarinics in male lower urinary tract symptoms based on the International Prostate Symptom Score subscore ratio.
    International journal of clinical practice, 2012, Volume: 66, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Benzhydryl Compounds; Cresols; Doxazosin; Feasibility

2012