doxazosin has been researched along with Liver Cirrhosis in 6 studies
Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study analyzed the effect of bone morphogenetic protein (BMP)‑7 gene therapy with or without co‑treatment with doxazosin in a model of liver cirrhosis in hamsters." | 3.85 | Adenoviral‑bone morphogenetic protein‑7 and/or doxazosin therapies promote the reversion of fibrosis/cirrhosis in a cirrhotic hamster model. ( Aldaba-Muruato, LR; Borrego-Soto, G; Cervantes-Garcia, D; Cuellar-Juarez, AG; Muñoz-Ortega, MH; Rojas-Martinez, A; Salinas, E; Ventura-Juarez, J, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Serna-Salas, SA | 1 |
| Arroyave-Ospina, JC | 1 |
| Zhang, M | 1 |
| Damba, T | 1 |
| Buist-Homan, M | 1 |
| Muñoz-Ortega, MH | 3 |
| Ventura-Juárez, J | 3 |
| Moshage, H | 1 |
| Xiu, AY | 1 |
| Ding, Q | 1 |
| Li, Z | 1 |
| Zhang, CQ | 1 |
| Cervantes-Garcia, D | 2 |
| Cuellar-Juarez, AG | 1 |
| Borrego-Soto, G | 1 |
| Rojas-Martinez, A | 1 |
| Aldaba-Muruato, LR | 1 |
| Salinas, E | 1 |
| Llamas-Ramírez, RW | 1 |
| Romero-Delgadillo, NI | 1 |
| Elías-Flores, TG | 1 |
| Tavares-Rodríguez, Ede J | 1 |
| Campos-Esparza, Mdel R | 1 |
| Muñoz-Fernández, L | 1 |
| Gerardo-Rodríguez, M | 1 |
| Paik, YH | 1 |
| Kalambokis, GN | 1 |
| Pappas, K | 1 |
| Tsianos, EV | 1 |
6 other studies available for doxazosin and Liver Cirrhosis
| Article | Year |
|---|---|
α-1 Adrenergic receptor antagonist doxazosin reverses hepatic stellate cells activation via induction of senescence.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Cell Cycle Checkpoints; | 2022 |
Doxazosin Attenuates Liver Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via Activation of the PI3K/Akt/mTOR Signaling Pathway.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Apoptosis; Autophagy; Carbon Tetrachloride; Cell L | 2021 |
Adenoviral‑bone morphogenetic protein‑7 and/or doxazosin therapies promote the reversion of fibrosis/cirrhosis in a cirrhotic hamster model.
Topics: Adenoviridae; Adrenergic alpha-Antagonists; Animals; Bone Morphogenetic Protein 7; Collagen Type I; | 2017 |
Doxazosin Treatment Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in Hamsters through a Decrease in Transforming Growth Factor β Secretion.
Topics: Adrenergic alpha-1 Receptor Antagonists; Alanine Transaminase; Animals; Aspartate Aminotransferases; | 2016 |
Reappraisal of Antihypertensive Medicine Doxazosin and Carvedilol as a Potential Therapeutic for Hepatic Fibrosis.
Topics: Antihypertensive Agents; Doxazosin; Humans; Liver Cirrhosis | 2016 |
Effect of alpha1-blockade with doxazosin in pulmonary hypertension associated with cirrhosis.
Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Doxazosin; Female; Humans; Hypertension, Pulmonary; L | 2010 |