doxazosin has been researched along with Liver Cirrhosis in 6 studies
Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
Excerpt | Relevance | Reference |
---|---|---|
" The present study analyzed the effect of bone morphogenetic protein (BMP)‑7 gene therapy with or without co‑treatment with doxazosin in a model of liver cirrhosis in hamsters." | 3.85 | Adenoviral‑bone morphogenetic protein‑7 and/or doxazosin therapies promote the reversion of fibrosis/cirrhosis in a cirrhotic hamster model. ( Aldaba-Muruato, LR; Borrego-Soto, G; Cervantes-Garcia, D; Cuellar-Juarez, AG; Muñoz-Ortega, MH; Rojas-Martinez, A; Salinas, E; Ventura-Juarez, J, 2017) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 4 (66.67) | 24.3611 |
2020's | 2 (33.33) | 2.80 |
Authors | Studies |
---|---|
Serna-Salas, SA | 1 |
Arroyave-Ospina, JC | 1 |
Zhang, M | 1 |
Damba, T | 1 |
Buist-Homan, M | 1 |
Muñoz-Ortega, MH | 3 |
Ventura-Juárez, J | 3 |
Moshage, H | 1 |
Xiu, AY | 1 |
Ding, Q | 1 |
Li, Z | 1 |
Zhang, CQ | 1 |
Cervantes-Garcia, D | 2 |
Cuellar-Juarez, AG | 1 |
Borrego-Soto, G | 1 |
Rojas-Martinez, A | 1 |
Aldaba-Muruato, LR | 1 |
Salinas, E | 1 |
Llamas-Ramírez, RW | 1 |
Romero-Delgadillo, NI | 1 |
Elías-Flores, TG | 1 |
Tavares-Rodríguez, Ede J | 1 |
Campos-Esparza, Mdel R | 1 |
Muñoz-Fernández, L | 1 |
Gerardo-Rodríguez, M | 1 |
Paik, YH | 1 |
Kalambokis, GN | 1 |
Pappas, K | 1 |
Tsianos, EV | 1 |
6 other studies available for doxazosin and Liver Cirrhosis
Article | Year |
---|---|
α-1 Adrenergic receptor antagonist doxazosin reverses hepatic stellate cells activation via induction of senescence.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Cell Cycle Checkpoints; | 2022 |
Doxazosin Attenuates Liver Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via Activation of the PI3K/Akt/mTOR Signaling Pathway.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Apoptosis; Autophagy; Carbon Tetrachloride; Cell L | 2021 |
Adenoviral‑bone morphogenetic protein‑7 and/or doxazosin therapies promote the reversion of fibrosis/cirrhosis in a cirrhotic hamster model.
Topics: Adenoviridae; Adrenergic alpha-Antagonists; Animals; Bone Morphogenetic Protein 7; Collagen Type I; | 2017 |
Doxazosin Treatment Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in Hamsters through a Decrease in Transforming Growth Factor β Secretion.
Topics: Adrenergic alpha-1 Receptor Antagonists; Alanine Transaminase; Animals; Aspartate Aminotransferases; | 2016 |
Reappraisal of Antihypertensive Medicine Doxazosin and Carvedilol as a Potential Therapeutic for Hepatic Fibrosis.
Topics: Antihypertensive Agents; Doxazosin; Humans; Liver Cirrhosis | 2016 |
Effect of alpha1-blockade with doxazosin in pulmonary hypertension associated with cirrhosis.
Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Doxazosin; Female; Humans; Hypertension, Pulmonary; L | 2010 |