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doxazosin and Liver Cirrhosis, Alcoholic

doxazosin has been researched along with Liver Cirrhosis, Alcoholic in 1 studies

Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.

Liver Cirrhosis, Alcoholic: FIBROSIS of the hepatic parenchyma due to chronic excess ALCOHOL DRINKING.

Research Excerpts

ExcerptRelevanceReference
"The pharmacokinetics of doxazosin was determined in an open-label study of 12 male volunteers with hepatic impairment (stable alcoholic cirrhosis) and 12 healthy male volunteers."5.09The effects of hepatic impairment on the pharmacokinetics of doxazosin. ( Chung, M; Penenberg, D; Vashi, V; Walmsley, P, 2000)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Penenberg, D1
Chung, M1
Walmsley, P1
Vashi, V1

Trials

1 trial available for doxazosin and Liver Cirrhosis, Alcoholic

ArticleYear
The effects of hepatic impairment on the pharmacokinetics of doxazosin.
    Journal of clinical pharmacology, 2000, Volume: 40, Issue:1

    Topics: Blood Pressure; Doxazosin; Electrocardiography; Heart Rate; Humans; Liver Cirrhosis, Alcoholic; Male

2000