doxazosin has been researched along with Hypotension, Orthostatic in 7 studies
Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
Hypotension, Orthostatic: A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This is an open non-comparative study to evaluate the efficacy and tolerability of doxazosin mesilate in 540 subjects with either history or newly diagnosed mild/moderate hypertension." | 9.08 | [Doxazosin in the treatment of light-to-moderate arterial hypertension in a non-comparative multicenter study]. ( Pessina, AC, 1995) |
| "This is an open non-comparative study to evaluate the efficacy and tolerability of doxazosin mesilate in 540 subjects with either history or newly diagnosed mild/moderate hypertension." | 5.08 | [Doxazosin in the treatment of light-to-moderate arterial hypertension in a non-comparative multicenter study]. ( Pessina, AC, 1995) |
| "dizziness and orthostatic hypotension)." | 2.40 | A meta-analysis on the efficacy and tolerability of alpha1-adrenoceptor antagonists in patients with lower urinary tract symptoms suggestive of benign prostatic obstruction. ( Djavan, B; Marberger, M, 1999) |
| "Patients on alpha-blockers (ABs) treatment may have an increased risk of adverse events (AEs)." | 1.91 | Adverse events related to alpha-blockers: analysis of real-life data from Eudra-Vigilance. ( Baldassarri, V; Cicione, A; D'Annunzio, S; DE Nunzio, C; Franco, A; Guarnotta, G; Lombardo, R; Mancini, E; Nacchia, A; Rovesti, LM; Tema, G; Tubaro, A; Voglino, OA, 2023) |
| "The patient demonstrated marked orthostatic hypotension without increment of heart rate, increased variability of blood pressure and abnormal hypertensive surges in a single 24 hour period, and abnormal response of heart rate during Valsalva's maneuver." | 1.34 | [Case of baroreflex failure after bilateral revascularization of the cervical carotid artery]. ( Azuma, Y; Imai, K; Makino, M; Niwa, F; Oda, K; Oshima, F, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Cicione, A | 1 |
| Nacchia, A | 1 |
| Baldassarri, V | 1 |
| Tema, G | 1 |
| Rovesti, LM | 1 |
| Mancini, E | 1 |
| Guarnotta, G | 1 |
| Voglino, OA | 1 |
| Franco, A | 1 |
| D'Annunzio, S | 1 |
| Lombardo, R | 1 |
| Tubaro, A | 1 |
| DE Nunzio, C | 1 |
| Azuma, Y | 1 |
| Imai, K | 1 |
| Oda, K | 1 |
| Niwa, F | 1 |
| Makino, M | 1 |
| Oshima, F | 1 |
| Pessina, AC | 1 |
| Cosenzi, A | 1 |
| Waltman, FL | 1 |
| van Es, PN | 1 |
| de Leeuw, PW | 1 |
| Djavan, B | 1 |
| Marberger, M | 1 |
| Hasegawa, K | 1 |
| McInnes, GT | 1 |
2 reviews available for doxazosin and Hypotension, Orthostatic
| Article | Year |
|---|---|
A meta-analysis on the efficacy and tolerability of alpha1-adrenoceptor antagonists in patients with lower urinary tract symptoms suggestive of benign prostatic obstruction.
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Controlled Clinical Trials as Topic; Dizzines | 1999 |
The value of alpha-blockers in the management of hypertension: a practical view.
Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Blood Pressure; Coronary Disease; Doxazosin; | 1991 |
2 trials available for doxazosin and Hypotension, Orthostatic
| Article | Year |
|---|---|
[Doxazosin in the treatment of light-to-moderate arterial hypertension in a non-comparative multicenter study].
Topics: Adult; Aged; Cholesterol; Dose-Response Relationship, Drug; Doxazosin; Edema; Female; Headache; Huma | 1995 |
Doxazosin versus nitrendipine: a double-blind comparative study in patients adhering to a sodium-restricted diet.
Topics: Adult; Biomarkers; Blood Glucose; Blood Pressure; Diet, Sodium-Restricted; Double-Blind Method; Doxa | 1994 |
3 other studies available for doxazosin and Hypotension, Orthostatic
| Article | Year |
|---|---|
Adverse events related to alpha-blockers: analysis of real-life data from Eudra-Vigilance.
Topics: Adrenergic alpha-Antagonists; Doxazosin; Humans; Hypotension, Orthostatic; Prazosin; Tamsulosin; Uro | 2023 |
[Case of baroreflex failure after bilateral revascularization of the cervical carotid artery].
Topics: Adrenergic alpha-Antagonists; Aged; Baroreflex; Carotid Artery, Internal; Carotid Stenosis; Diagnosi | 2007 |
[Effect of doxazosin on postural changes in blood pressure using a multibiomedical recorder].
Topics: Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitori | 2001 |