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doxazosin and Glomerulosclerosis, Focal Segmental

doxazosin has been researched along with Glomerulosclerosis, Focal Segmental in 1 studies

Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.

Glomerulosclerosis, Focal Segmental: A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.

Research Excerpts

ExcerptRelevanceReference
"Both doxazosin treatment and good glycemic control normalized these abnormalities in diabetic rats."5.29Doxazosin prevents proteinuria and glomerular loss of heparan sulfate in diabetic rats. ( Alluru, I; Jyothirmayi, GN; Reddi, AS, 1996)
"Both doxazosin treatment and good glycemic control normalized these abnormalities in diabetic rats."1.29Doxazosin prevents proteinuria and glomerular loss of heparan sulfate in diabetic rats. ( Alluru, I; Jyothirmayi, GN; Reddi, AS, 1996)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jyothirmayi, GN1
Alluru, I1
Reddi, AS1

Other Studies

1 other study available for doxazosin and Glomerulosclerosis, Focal Segmental

ArticleYear
Doxazosin prevents proteinuria and glomerular loss of heparan sulfate in diabetic rats.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:5

    Topics: Adrenergic alpha-Antagonists; Albuminuria; Animals; Blood Glucose; Blood Pressure; Diabetes Mellitus

1996