doxazosin has been researched along with Genetic Predisposition in 3 studies
Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the present study was to analyse the nitric oxide (NO)/cyclic GMP (cGMP) relaxing system in spontaneously hypertensive rats of the stroke-prone substrain (SHRSP)." | 7.71 | Reduction of the soluble cyclic GMP vasorelaxing system in the vascular wall of stroke-prone spontaneously hypertensive rats: effect of the alpha1 -receptor blocker doxazosin. ( Casado, S; de Andrés, R; Fortes, J; García-Colis, E; Gomez, J; López-Blaya, A; López-Farré, A; Rico, L; Rodriguez-Feo, JA, 2002) |
| "The aim of the present study was to analyse the nitric oxide (NO)/cyclic GMP (cGMP) relaxing system in spontaneously hypertensive rats of the stroke-prone substrain (SHRSP)." | 3.71 | Reduction of the soluble cyclic GMP vasorelaxing system in the vascular wall of stroke-prone spontaneously hypertensive rats: effect of the alpha1 -receptor blocker doxazosin. ( Casado, S; de Andrés, R; Fortes, J; García-Colis, E; Gomez, J; López-Blaya, A; López-Farré, A; Rico, L; Rodriguez-Feo, JA, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fernández-Cruz, L | 1 |
| Puig-Domingo, M | 1 |
| Halperin, I | 1 |
| Sesmilo, G | 1 |
| Davis, BR | 1 |
| Arnett, DK | 1 |
| Boerwinkle, E | 1 |
| Ford, CE | 1 |
| Leiendecker-Foster, C | 1 |
| Miller, MB | 1 |
| Black, H | 1 |
| Eckfeldt, JH | 1 |
| López-Farré, A | 1 |
| Rodriguez-Feo, JA | 1 |
| García-Colis, E | 1 |
| Gomez, J | 1 |
| López-Blaya, A | 1 |
| Fortes, J | 1 |
| de Andrés, R | 1 |
| Rico, L | 1 |
| Casado, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| GenHAT - Genetics of Hypertension Associated Treatments - Ancillary to ALLHAT[NCT00563901] | 37,939 participants (Actual) | Observational | 2000-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for doxazosin and Genetic Predisposition
| Article | Year |
|---|---|
Pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; alpha-Methyltyrosine; Calcium Channel Blockers; Combined Mo | 2004 |
1 trial available for doxazosin and Genetic Predisposition
| Article | Year |
|---|---|
Antihypertensive therapy, the alpha-adducin polymorphism, and cardiovascular disease in high-risk hypertensive persons: the Genetics of Hypertension-Associated Treatment Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Chlorthalido | 2007 |
1 other study available for doxazosin and Genetic Predisposition
| Article | Year |
|---|---|
Reduction of the soluble cyclic GMP vasorelaxing system in the vascular wall of stroke-prone spontaneously hypertensive rats: effect of the alpha1 -receptor blocker doxazosin.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Aorta; Cyclic GMP; Doxazosin; Endothelium, Vas | 2002 |