doxazosin has been researched along with Diabetes Mellitus, Type 1 in 6 studies
Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Doxazosin was generally well-tolerated; four patients (29%) reported mild-to-moderate treatment-related adverse events." | 6.69 | Hand vein responses to noradrenaline in normotensive patients with insulin-dependent diabetes mellitus and microalbuminuria: effects of alpha-adrenoceptor blockade with doxazosin. ( Bodmer, CW; Lake, D; Savage, MW; Williams, G, 1999) |
| "Enalapril, but not doxazosin, reduces albuminuria in insulin dependent diabetes mellitus patients with nephropathy." | 5.08 | Contrasting effects of angiotensin converting inhibitor and alpha-1-antagonist on albuminuria in insulin-dependent diabetes mellitus patients with nephropathy. ( Berg, KJ; Blystad, L; Fauchald, P; Hartmann, A; Holdaas, H; Langberg, H, 1995) |
| "The effect of doxazosin versus captopril on blood pressure, albuminuria, and left ventricular mass was studied in 33 hypertensive type-1 diabetic patients randomized to 6 months treatment with captopril (17 patients, mean daily dose 100 mg) or doxazosin (16 patients, mean daily dose 9 mg)." | 5.08 | Factors influencing reduction in blood pressure and left ventricular mass in hypertensive type-1 diabetic patients using captopril or doxazosin for 6 months. ( Aanderud, S; Gerdts, E; Lund-Johansen, P; Myking, OL; Omvik, P; Svarstad, E, 1998) |
| "Doxazosin was generally well-tolerated; four patients (29%) reported mild-to-moderate treatment-related adverse events." | 2.69 | Hand vein responses to noradrenaline in normotensive patients with insulin-dependent diabetes mellitus and microalbuminuria: effects of alpha-adrenoceptor blockade with doxazosin. ( Bodmer, CW; Lake, D; Savage, MW; Williams, G, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Holdaas, H | 1 |
| Hartmann, A | 1 |
| Berg, KJ | 1 |
| Langberg, H | 1 |
| Blystad, L | 1 |
| Fauchald, P | 1 |
| Calò, L | 1 |
| Davis, PA | 1 |
| Cantaro, S | 1 |
| Bonfante, L | 1 |
| Castrignano, R | 1 |
| Carraro, G | 1 |
| D'Angelo, A | 2 |
| Gerdts, E | 2 |
| Svarstad, E | 2 |
| Aanderud, S | 1 |
| Myking, OL | 1 |
| Lund-Johansen, P | 1 |
| Omvik, P | 2 |
| Bodmer, CW | 1 |
| Lake, D | 1 |
| Savage, MW | 1 |
| Williams, G | 1 |
| Ofstad, J | 1 |
| Iversen, BM | 1 |
| Nosadini, R | 1 |
| Crepaldi, G | 1 |
4 trials available for doxazosin and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Contrasting effects of angiotensin converting inhibitor and alpha-1-antagonist on albuminuria in insulin-dependent diabetes mellitus patients with nephropathy.
Topics: Adult; Albuminuria; Creatinine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Doxazosin; Enalap | 1995 |
Effect of doxazosin in mild to moderate hypertensive patients with insulin-dependent diabetes mellitus.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Blood Pressure; Coronary Disease; Diabetes Me | 1998 |
Factors influencing reduction in blood pressure and left ventricular mass in hypertensive type-1 diabetic patients using captopril or doxazosin for 6 months.
Topics: Adult; Albuminuria; Antihypertensive Agents; Blood Pressure; Captopril; Diabetes Mellitus, Type 1; D | 1998 |
Hand vein responses to noradrenaline in normotensive patients with insulin-dependent diabetes mellitus and microalbuminuria: effects of alpha-adrenoceptor blockade with doxazosin.
Topics: Adrenergic alpha-Antagonists; Adult; Albuminuria; Analysis of Variance; Consumer Product Safety; Dia | 1999 |
2 other studies available for doxazosin and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Renal hemodynamic effects of captopril and doxazosin during slight physical activity in hypertensive patients with type-1 diabetes mellitus.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Captopril; Diabetes Mellitus, Type 1; Doxazosi | 2001 |
Diabetes mellitus and hypertension: a physiologic basis for a rational therapeutic approach.
Topics: Antihypertensive Agents; Biological Transport; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; | 1991 |