Page last updated: 2024-10-26

doxazosin and Complication, Postoperative

doxazosin has been researched along with Complication, Postoperative in 16 studies

Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.

Research Excerpts

ExcerptRelevanceReference
"No conclusion exists for the optimum duration of preoperative administration of doxazosin (DOX) before adrenalectomy for pheochromocytoma."7.96The use of doxazosin before adrenalectomy for pheochromocytoma: is the duration related to intraoperative hemodynamics and postoperative complications? ( Bao, Z; Fang, D; Gao, Y; Jin, B; Kong, H; Li, N; Liu, L; Tian, J; Wu, K; Zhang, J; Zhang, Z; Zhou, L, 2020)
"To compare phenoxybenzamine (PhB) and doxazosin (DOX) in terms of perioperative haemodynamic status in patients with pheochromocytoma, who have been prepared for adrenalectomy."7.85Comparison of phenoxybenzamine and doxazosin in perioperative management of patients with pheochromocytoma. ( Ambroziak, U; Bednarczuk, T; Gałązka, Z; Kącka, A; Krajewska, E; Malec, K; Miśkiewicz, P; Piotrowski, M; Toutounchi, S; Witkowska, A, 2017)
"Doxazosin GITS is a safe agent which can reduce cardiovascular risk."6.71Doxazosin GITS trough to peak ratio and 24-hour blood pressure monitoring in the management of hypertension in renal transplant patients. ( Grinyó, JM; Ibernón, M; Martínez Castelao, A; Moreso, F; Rama, I; Sanz, V; Sarrias, X, 2003)
"No conclusion exists for the optimum duration of preoperative administration of doxazosin (DOX) before adrenalectomy for pheochromocytoma."3.96The use of doxazosin before adrenalectomy for pheochromocytoma: is the duration related to intraoperative hemodynamics and postoperative complications? ( Bao, Z; Fang, D; Gao, Y; Jin, B; Kong, H; Li, N; Liu, L; Tian, J; Wu, K; Zhang, J; Zhang, Z; Zhou, L, 2020)
"To compare phenoxybenzamine (PhB) and doxazosin (DOX) in terms of perioperative haemodynamic status in patients with pheochromocytoma, who have been prepared for adrenalectomy."3.85Comparison of phenoxybenzamine and doxazosin in perioperative management of patients with pheochromocytoma. ( Ambroziak, U; Bednarczuk, T; Gałązka, Z; Kącka, A; Krajewska, E; Malec, K; Miśkiewicz, P; Piotrowski, M; Toutounchi, S; Witkowska, A, 2017)
" Laboratory tests were performed, adverse events recorded, and prostatic symptomatology examined."2.71Efficacy and safety of doxazosin GITS in hypertensive renal transplant patients: comparison of 8 and 4 mg. ( Hurtado, S; Lloveras, J; Oliveras, A; Puig, JM; Vázquez, S, 2003)
"Doxazosin GITS is a safe agent which can reduce cardiovascular risk."2.71Doxazosin GITS trough to peak ratio and 24-hour blood pressure monitoring in the management of hypertension in renal transplant patients. ( Grinyó, JM; Ibernón, M; Martínez Castelao, A; Moreso, F; Rama, I; Sanz, V; Sarrias, X, 2003)
"In conclusion, intraoperative complications in pheochromocytoma surgery are common and can be potentially life-threatening."1.62Risk factors for intraoperative complications in pheochromocytomas. ( Álvarez-Escolá, C; Araujo-Castro, M; Blanco-Carrera, C; Calatayud Gutiérrez, M; de Miguel Novoa, P; Fernández-Ladreda, MT; Garcia Centeno, R; Gómez Dos Santos, V; Gracia Gimeno, P; Hanzu, FA; Lamas, C; López-García, MC; Mínguez Ojeda, C; Mora, M; Percovich Hualpa, JC; Serrano Romero, A; Valdés, N; Vidal, Ó, 2021)
"The patient demonstrated marked orthostatic hypotension without increment of heart rate, increased variability of blood pressure and abnormal hypertensive surges in a single 24 hour period, and abnormal response of heart rate during Valsalva's maneuver."1.34[Case of baroreflex failure after bilateral revascularization of the cervical carotid artery]. ( Azuma, Y; Imai, K; Makino, M; Niwa, F; Oda, K; Oshima, F, 2007)
"Sirolimus is an immunosuppressive drug which has proved its effectivity to reduce the incidence of acute rejection in renal transplantation receptors."1.32[Interstitial pneumonitis associated with sirolimus administration in a renal transplantation patient: a clinical case]. ( Gentil, MA; González Roncero, FM; López, M; Martínez, M; Mateos, J; Pereira, P; Rodríguez Algarra, G; Toro, J; Valdivia, MA, 2004)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's8 (50.00)29.6817
2010's3 (18.75)24.3611
2020's4 (25.00)2.80

Authors

AuthorsStudies
Kong, H1
Li, N1
Tian, J1
Bao, Z1
Liu, L1
Wu, K1
Gao, Y1
Jin, B1
Zhang, Z1
Fang, D1
Zhang, J1
Zhou, L1
Iglesias, P1
Santacruz, E1
García-Sancho, P1
Marengo, AP1
Guerrero-Pérez, F1
Pian, H1
Fajardo, C1
Villabona, C1
Díez, JJ1
Araujo-Castro, M1
Garcia Centeno, R1
López-García, MC1
Lamas, C1
Álvarez-Escolá, C1
Calatayud Gutiérrez, M1
Blanco-Carrera, C1
de Miguel Novoa, P1
Valdés, N1
Gracia Gimeno, P1
Fernández-Ladreda, MT1
Mínguez Ojeda, C1
Percovich Hualpa, JC1
Mora, M1
Vidal, Ó1
Serrano Romero, A1
Hanzu, FA1
Gómez Dos Santos, V1
Zheng, Y1
Bai, F1
Zhang, N1
Wu, H1
Malec, K1
Miśkiewicz, P1
Witkowska, A1
Krajewska, E1
Toutounchi, S1
Gałązka, Z1
Piotrowski, M1
Kącka, A1
Bednarczuk, T1
Ambroziak, U1
Drzayich Antol, D1
Waldman Casebeer, A1
Khoury, R1
Michael, T1
Renda, A1
Hopson, S1
Parikh, A1
Stein, A1
Costantino, M1
Stemkowski, S1
Bunce, M1
Nevo, N1
Abu-Abeid, S1
Hazzan, D1
Lahat, G1
Nachmani, I1
Eldar, SM1
Zhang, L1
Xia, X1
Zhong, Y1
Xie, D1
Liu, S1
Wang, X1
Tu, J1
Faconti, L1
Mills, CE1
Govoni, V1
Gu, H1
Morant, S1
Jiang, B1
Cruickshank, JK1
Webb, AJ1
Lin, J1
Wu, YJ1
Liang, X1
Ji, M1
Ying, HM1
Wang, XY1
Sun, X1
Shao, CH1
Zhan, LX1
Zhang, Y2
Czamara, K1
Karnas, E1
Majka, Z1
Wojcik, T1
Zuba-Surma, EK1
Baranska, M1
Kaczor, A1
Liu, X1
Zhou, F1
Yang, Y2
Wang, W1
Niu, L1
Zuo, D1
Li, X1
Hua, H1
Zhang, B1
Kou, Y1
Guo, J1
Kong, F1
Pan, W1
Gao, D1
Meves, JM1
Sun, H1
Xue, M1
Zhang, Q1
Wang, Y2
Tang, R1
Iso, T1
Haruyama, H1
Sunaga, H1
Matsui, H1
Matsui, M1
Tanaka, R1
Umbarawan, Y1
Syamsunarno, MRAA1
Putri, M1
Yamaguchi, A1
Hanaoka, H1
Negishi, K1
Yokoyama, T1
Kurabayashi, M1
Palomo-Briones, R1
Esquivel-González, S1
Aizpuru, A1
Gómez-Hernández, N1
Casas-Flores, S1
Barba de la Rosa, AP1
Arriaga, S1
Peterson, ME1
Carothers, MA1
Gamble, DA1
Rishniw, M1
Zhang, P1
Zhang, XD1
Shao, Y1
Chen, R1
Shen, ZJ1
Teng, Y1
Huang, P1
Rui, WB1
Xie, X1
Zhou, WL1
Merrick, GS1
Butler, WM1
Wallner, KE1
Lief, JH1
Galbreath, RW1
Oliveras, A1
Hurtado, S1
Vázquez, S1
Puig, JM1
Lloveras, J1
Martínez Castelao, A1
Ibernón, M1
Sarrias, X1
Sanz, V3
Moreso, F1
Rama, I1
Grinyó, JM3
Martínez, M1
González Roncero, FM1
López, M1
Toro, J1
Valdivia, MA1
Pereira, P1
Gentil, MA1
Rodríguez Algarra, G1
Mateos, J1
Azuma, Y1
Imai, K1
Oda, K1
Niwa, F1
Makino, M1
Oshima, F1
Martínez-Castelao, A2
Hueso, M2
Rejas, J2
Alsina, J2
Blanchard, K1
Hananel, A1
Rutchik, S1
Sullivan, J1
Sarrias, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study for Randomized Controlled Trial on the Effect and Safety of Omitting Preoperative Alpha-adrenergic Blockade for Normotensive Pheochromocytoma[NCT05702944]Phase 424 participants (Anticipated)Interventional2023-01-18Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

6 trials available for doxazosin and Complication, Postoperative

ArticleYear
    Journal of patient-reported outcomes, 2018, Volume: 2

    Topics: Adult; Aged; Animals; Astrocytes; Bariatric Surgery; Beta vulgaris; Bioreactors; Biotechnology; Bloo

2018
Prophylactic versus therapeutic alpha-blockers after permanent prostate brachytherapy.
    Urology, 2002, Volume: 60, Issue:4

    Topics: Adenocarcinoma; Adrenergic alpha-Antagonists; Biopsy; Brachytherapy; Doxazosin; Follow-Up Studies; H

2002
Efficacy and safety of doxazosin GITS in hypertensive renal transplant patients: comparison of 8 and 4 mg.
    Transplantation proceedings, 2003, Volume: 35, Issue:5

    Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Dose-Resp

2003
Doxazosin GITS trough to peak ratio and 24-hour blood pressure monitoring in the management of hypertension in renal transplant patients.
    Transplantation proceedings, 2003, Volume: 35, Issue:5

    Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Doxazosin; Female; H

2003
Treatment of hypertension after renal transplantation: long-term efficacy of verapamil, enalapril, and doxazosin.
    Kidney international. Supplement, 1998, Volume: 68

    Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Doxazosin; Enalapril; Female; Follow-Up St

1998
Double-blind, crossover, comparative study of doxazosin and enalapril in the treatment of hypertension in renal transplant patients under cyclosporine immunosuppression.
    Transplantation proceedings, 2002, Volume: 34, Issue:1

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood Press

2002

Other Studies

10 other studies available for doxazosin and Complication, Postoperative

ArticleYear
The use of doxazosin before adrenalectomy for pheochromocytoma: is the duration related to intraoperative hemodynamics and postoperative complications?
    International urology and nephrology, 2020, Volume: 52, Issue:11

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenergic alpha-1 Receptor Antagonists; Adult; Aged; Doxazo

2020
Pheochromocytoma: A three-decade clinical experience in a multicenter study.
    Revista clinica espanola, 2021, Volume: 221, Issue:1

    Topics: 3-Iodobenzylguanidine; Adolescent; Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adult; Age

2021
Risk factors for intraoperative complications in pheochromocytomas.
    Endocrine-related cancer, 2021, 09-08, Volume: 28, Issue:11

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Doxazosin; Female; Humans; Hydrocortisone; Hypo

2021
Analysis of Voiding Impairment after Prostate Biopsy and the Effect of Doxazosin Treatment: Outcomes from a Regional Cancer Center.
    Urologia internationalis, 2022, Volume: 106, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Doxazosin; Humans; Image-Guided Biopsy; Male; Postope

2022
Comparison of phenoxybenzamine and doxazosin in perioperative management of patients with pheochromocytoma.
    Kardiologia polska, 2017, Volume: 75, Issue:11

    Topics: Adrenalectomy; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Disease Mana

2017
Extended-release doxazosin for treatment of renal transplant recipients with benign prostatic hyperplasia.
    Transplantation proceedings, 2009, Volume: 41, Issue:9

    Topics: Adrenergic alpha-Antagonists; Aged; Blood Urea Nitrogen; Delayed-Action Preparations; Doxazosin; Fam

2009
Preoperative alpha blockade for normotensive pheochromocytoma: is it necessary?
    Journal of hypertension, 2011, Volume: 29, Issue:12

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenergic alpha-Antagonists; Adult; Blood Pressure; Doxazos

2011
[Interstitial pneumonitis associated with sirolimus administration in a renal transplantation patient: a clinical case].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2004, Volume: 24 Suppl 3

    Topics: Aged; Antilymphocyte Serum; Azathioprine; Cyclosporine; Diagnosis, Differential; Diuretics; Doxazosi

2004
[Case of baroreflex failure after bilateral revascularization of the cervical carotid artery].
    Rinsho shinkeigaku = Clinical neurology, 2007, Volume: 47, Issue:10

    Topics: Adrenergic alpha-Antagonists; Aged; Baroreflex; Carotid Artery, Internal; Carotid Stenosis; Diagnosi

2007
Transurethral resection of the prostate: failure patterns and surgical outcomes in patients with symptoms refractory to alpha-antagonists.
    Southern medical journal, 2000, Volume: 93, Issue:12

    Topics: Adrenergic alpha-Antagonists; Aged; Comorbidity; Doxazosin; Humans; Louisiana; Male; Postoperative C

2000