Page last updated: 2024-10-26

doxazosin and Complication, Intraoperative

doxazosin has been researched along with Complication, Intraoperative in 22 studies

Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.

Research Excerpts

ExcerptRelevanceReference
"The association between intraoperative floppy iris syndrome (IFIS) and tamsulosin has been well-described."7.79Intraoperative floppy iris syndrome (IFIS) in patients receiving tamsulosin or doxazosin-a UK-based comparison of incidence and complication rates. ( Al-Ahmar, B; Haridas, A; Hingorani, M; Syrimi, M, 2013)
"The objective of this article is to evaluate the efficacy of Doxazosin Mesylate Controlled Release Tablets for preoperative treatment of patients with pheochromocytoma."5.14Selective α1-adrenoceptor antagonist (controlled release tablets) in preoperative management of pheochromocytoma. ( He, HC; Ning, G; Rui, WB; Shen, Z; Su, TW; Sun, FK; Wang, WQ; Wu, YX; Zhang, CY; Zhao, JP; Zhou, WL; Zhu, Y, 2010)
"To evaluate risk factors (hypertension, diabetes mellitus, and current tamsulosin, alfuzosin, terazosin, or doxazosin use) for intraoperative floppy iris syndrome (IFIS) in patients undergoing phacoemulsification cataract surgery."4.87Risk factors for intraoperative floppy iris syndrome: a meta-analysis. ( Chatziralli, IP; Sergentanis, TN, 2011)
"The association between intraoperative floppy iris syndrome (IFIS) and tamsulosin has been well-described."3.79Intraoperative floppy iris syndrome (IFIS) in patients receiving tamsulosin or doxazosin-a UK-based comparison of incidence and complication rates. ( Al-Ahmar, B; Haridas, A; Hingorani, M; Syrimi, M, 2013)
"In conclusion, intraoperative complications in pheochromocytoma surgery are common and can be potentially life-threatening."1.62Risk factors for intraoperative complications in pheochromocytomas. ( Álvarez-Escolá, C; Araujo-Castro, M; Blanco-Carrera, C; Calatayud Gutiérrez, M; de Miguel Novoa, P; Fernández-Ladreda, MT; Garcia Centeno, R; Gómez Dos Santos, V; Gracia Gimeno, P; Hanzu, FA; Lamas, C; López-García, MC; Mínguez Ojeda, C; Mora, M; Percovich Hualpa, JC; Serrano Romero, A; Valdés, N; Vidal, Ó, 2021)
"As a surgical treatment of pheochromocytomas, laparoscopic adrenalectomy is an effective and safe approach, in selected cases even for PCCs >6 cm in diameter, although patients with such large tumors may have a higher conversion rate and more intraoperative hypertensive crises."1.39Laparoscopic adrenalectomy, a safe procedure for pheochromocytoma. A retrospective review of clinical series. ( Colantuoni, V; Conzo, G; Corcione, F; De Palma, M; Ferraro, F; Milone, M; Musella, M; Napolitano, S; Palazzo, A; Pasquali, D; Santini, L; Sinisi, AA, 2013)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (45.45)29.6817
2010's11 (50.00)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Araujo-Castro, M1
Garcia Centeno, R1
López-García, MC1
Lamas, C1
Álvarez-Escolá, C1
Calatayud Gutiérrez, M1
Blanco-Carrera, C1
de Miguel Novoa, P1
Valdés, N1
Gracia Gimeno, P1
Fernández-Ladreda, MT1
Mínguez Ojeda, C1
Percovich Hualpa, JC1
Mora, M1
Vidal, Ó1
Serrano Romero, A1
Hanzu, FA1
Gómez Dos Santos, V1
Haridas, A1
Syrimi, M1
Al-Ahmar, B1
Hingorani, M1
Grzybowski, A1
Krzyżanowska-Berkowska, P1
Mamalis, N1
Ganesh, HK1
Acharya, SV1
Goerge, J1
Bandgar, TR1
Menon, PS1
Shah, NS1
Nakaigawa, N1
Komatsu, R1
Kamata, K1
Ozaki, M1
Zhu, Y1
He, HC1
Su, TW1
Wu, YX1
Wang, WQ1
Zhao, JP1
Shen, Z1
Zhang, CY1
Rui, WB2
Zhou, WL2
Sun, FK1
Ning, G1
Chatziralli, IP1
Sergentanis, TN1
Scholten, A1
Vriens, MR1
Cromheecke, GJ1
Borel Rinkes, IH1
Valk, GD1
Casuccio, A1
Cillino, G1
Pavone, C1
Spitale, E1
Cillino, S1
Shao, Y1
Chen, R1
Shen, ZJ1
Teng, Y1
Huang, P1
Xie, X1
Groeben, H1
Gkaliagkousi, E1
Gavriilaki, E1
Nikolaidou, B1
Conzo, G1
Musella, M1
Corcione, F1
De Palma, M1
Ferraro, F1
Palazzo, A1
Napolitano, S1
Milone, M1
Pasquali, D1
Sinisi, AA1
Colantuoni, V1
Santini, L1
Schwinn, DA1
Afshari, NA1
El-Ghatit, AM1
Muqit, MM1
Menage, MJ1
Dhingra, N1
Rajkumar, KN1
Kumar, V1
Herd, MK1
Cheung, CM1
Awan, MA1
Peh, KK1
Sandramouli, S1
Taylor, MJ1
McIndoe, A1
Williams, GP1
Tsaloumas, MD1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Systemic Alfuzosin and Tamsulosin Hydrochloride on Choroidal Thickness and Pupil Diameter Sizes in Cases With Benign Prostatic Hyperplasia[NCT03144596]Phase 463 participants (Actual)Interventional2015-10-29Completed
A Pilot Study for Randomized Controlled Trial on the Effect and Safety of Omitting Preoperative Alpha-adrenergic Blockade for Normotensive Pheochromocytoma[NCT05702944]Phase 424 participants (Anticipated)Interventional2023-01-18Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for doxazosin and Complication, Intraoperative

ArticleYear
Risk factors for intraoperative floppy iris syndrome: a meta-analysis.
    Ophthalmology, 2011, Volume: 118, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Diabetes Complications; Doxazosin; Humans; Hypertension; In

2011
[Preoperative α-receptor block in patients with pheochromocytoma? Against].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2012, Volume: 83, Issue:6

    Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Asymptomatic Diseases; Blood Pressure; Catech

2012

Trials

1 trial available for doxazosin and Complication, Intraoperative

ArticleYear
Selective α1-adrenoceptor antagonist (controlled release tablets) in preoperative management of pheochromocytoma.
    Endocrine, 2010, Volume: 38, Issue:2

    Topics: Adolescent; Adrenal Gland Neoplasms; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antag

2010

Other Studies

19 other studies available for doxazosin and Complication, Intraoperative

ArticleYear
Risk factors for intraoperative complications in pheochromocytomas.
    Endocrine-related cancer, 2021, 09-08, Volume: 28, Issue:11

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Doxazosin; Female; Humans; Hydrocortisone; Hypo

2021
Intraoperative floppy iris syndrome (IFIS) in patients receiving tamsulosin or doxazosin-a UK-based comparison of incidence and complication rates.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2013, Volume: 251, Issue:6

    Topics: Adrenergic alpha-1 Receptor Antagonists; Atropine; Doxazosin; Drug Therapy, Combination; Female; Hum

2013
Intraoperative floppy iris syndrome (IFIS): what complication rates can we expect?
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2014, Volume: 252, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Doxazosin; Female; Humans; Intraoperative Complications; Ir

2014
Intraoperative floppy-iris syndrome associated with systemic alpha blockers.
    Journal of cataract and refractive surgery, 2008, Volume: 34, Issue:7

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Cataract Extraction; Doxazosi

2008
Pheochromocytoma in children and adolescents.
    Indian journal of pediatrics, 2009, Volume: 76, Issue:11

    Topics: Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adrenergic alpha-Antagonists; Child; Doxazosin;

2009
[Anesthetic management of a patient with pheochromocytoma and end-stage renal disease].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59, Issue:6

    Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Anesthesia, General; Cervical Vertebrae; Chro

2010
Hemodynamic instability during resection of pheochromocytoma in MEN versus non-MEN patients.
    European journal of endocrinology, 2011, Volume: 165, Issue:1

    Topics: Adrenal Gland Neoplasms; Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagon

2011
Pharmacologic pupil dilation as a predictive test for the risk for intraoperative floppy-iris syndrome.
    Journal of cataract and refractive surgery, 2011, Volume: 37, Issue:8

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Cohort Studies; Doxazosin; Drug Combinations; Humans;

2011
Preoperative alpha blockade for normotensive pheochromocytoma: is it necessary?
    Journal of hypertension, 2011, Volume: 29, Issue:12

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenergic alpha-Antagonists; Adult; Blood Pressure; Doxazos

2011
Clarifying the role of preoperative α-blockade in pheochromocytoma?
    Journal of hypertension, 2012, Volume: 30, Issue:5

    Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Doxazosin; Female; Humans; Intraoperative Com

2012
Laparoscopic adrenalectomy, a safe procedure for pheochromocytoma. A retrospective review of clinical series.
    International journal of surgery (London, England), 2013, Volume: 11, Issue:2

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenergic alpha-1 Receptor Antagonists; Adult; Doxazosin; F

2013
Alpha1-adrenergic antagonists and floppy iris syndrome: tip of the iceberg?
    Ophthalmology, 2005, Volume: 112, Issue:12

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Do

2005
Association of IFIS and vasodepressor medication.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Doxazosin; Humans; Hypertensi

2006
Intraoperative floppy iris syndrome.
    Ophthalmology, 2006, Volume: 113, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Doxazosin; Humans; Hyal

2006
Intraoperative floppy iris syndrome with doxazosin.
    Eye (London, England), 2007, Volume: 21, Issue:5

    Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Doxazosin; Humans; Intraoperative Complicatio

2007
Intraoperative floppy-iris syndrome with doxazosin.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Cataract Extraction; Doxazosi

2007
Incidence of intraoperative floppy iris syndrome in patients on either systemic or topical alpha1-adrenoceptor antagonist.
    American journal of ophthalmology, 2007, Volume: 143, Issue:6

    Topics: Administration, Topical; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adul

2007
Unresponsive asystolic cardiac arrest responding to external cardiac pacing in a patient with phaeochromocytoma.
    Anaesthesia, 2007, Volume: 62, Issue:8

    Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Cardiac Pacing, Artificial; Doxazosin; Female

2007
The use of intracameral phenylephrine in the management of intraoperative floppy-iris syndrome with doxazosin.
    Eye (London, England), 2008, Volume: 22, Issue:8

    Topics: Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Doxazosin; Humans; Intraoperative Compl

2008