Page last updated: 2024-10-26

doxazosin and Cirrhosis, Liver

doxazosin has been researched along with Cirrhosis, Liver in 6 studies

Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.

Research Excerpts

ExcerptRelevanceReference
" The present study analyzed the effect of bone morphogenetic protein (BMP)‑7 gene therapy with or without co‑treatment with doxazosin in a model of liver cirrhosis in hamsters."3.85Adenoviral‑bone morphogenetic protein‑7 and/or doxazosin therapies promote the reversion of fibrosis/cirrhosis in a cirrhotic hamster model. ( Aldaba-Muruato, LR; Borrego-Soto, G; Cervantes-Garcia, D; Cuellar-Juarez, AG; Muñoz-Ortega, MH; Rojas-Martinez, A; Salinas, E; Ventura-Juarez, J, 2017)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Serna-Salas, SA1
Arroyave-Ospina, JC1
Zhang, M1
Damba, T1
Buist-Homan, M1
Muñoz-Ortega, MH3
Ventura-Juárez, J3
Moshage, H1
Xiu, AY1
Ding, Q1
Li, Z1
Zhang, CQ1
Cervantes-Garcia, D2
Cuellar-Juarez, AG1
Borrego-Soto, G1
Rojas-Martinez, A1
Aldaba-Muruato, LR1
Salinas, E1
Llamas-Ramírez, RW1
Romero-Delgadillo, NI1
Elías-Flores, TG1
Tavares-Rodríguez, Ede J1
Campos-Esparza, Mdel R1
Muñoz-Fernández, L1
Gerardo-Rodríguez, M1
Paik, YH1
Kalambokis, GN1
Pappas, K1
Tsianos, EV1

Other Studies

6 other studies available for doxazosin and Cirrhosis, Liver

ArticleYear
α-1 Adrenergic receptor antagonist doxazosin reverses hepatic stellate cells activation via induction of senescence.
    Mechanisms of ageing and development, 2022, Volume: 201

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Cell Cycle Checkpoints;

2022
Doxazosin Attenuates Liver Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via Activation of the PI3K/Akt/mTOR Signaling Pathway.
    Drug design, development and therapy, 2021, Volume: 15

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Apoptosis; Autophagy; Carbon Tetrachloride; Cell L

2021
Adenoviral‑bone morphogenetic protein‑7 and/or doxazosin therapies promote the reversion of fibrosis/cirrhosis in a cirrhotic hamster model.
    Molecular medicine reports, 2017, Volume: 16, Issue:6

    Topics: Adenoviridae; Adrenergic alpha-Antagonists; Animals; Bone Morphogenetic Protein 7; Collagen Type I;

2017
Doxazosin Treatment Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in Hamsters through a Decrease in Transforming Growth Factor β Secretion.
    Gut and liver, 2016, Volume: 10, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Alanine Transaminase; Animals; Aspartate Aminotransferases;

2016
Reappraisal of Antihypertensive Medicine Doxazosin and Carvedilol as a Potential Therapeutic for Hepatic Fibrosis.
    Gut and liver, 2016, Volume: 10, Issue:1

    Topics: Antihypertensive Agents; Doxazosin; Humans; Liver Cirrhosis

2016
Effect of alpha1-blockade with doxazosin in pulmonary hypertension associated with cirrhosis.
    Scandinavian journal of gastroenterology, 2010, Volume: 45, Issue:9

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Doxazosin; Female; Humans; Hypertension, Pulmonary; L

2010