doxazosin has been researched along with Chronic Kidney Failure in 12 studies
Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Insulin resistance (IR) in chronic renal failure (CRF) is well-known." | 6.70 | Doxazosin, but not amlodipine decreases insulin resistance in patients with chronic renal failure: a prospective, randomized-controlled study. ( Akkaya, V; Celik, AV; Gürol, AO; Hursit, M; Karsidag, K; Kayacan, SM; Yazici, H; Yildiz, A, 2002) |
| " In this article, doxazosin is reviewed for its efficacy in the treatment of severe essential hypertension and specific complications or conditions of mild or moderate essential hypertension, namely, left ventricular hypertrophy, hyperlipidemia, noninsulin-dependent diabetes mellitus, renal insufficiency, pheochromocytoma, chronic obstructive pulmonary disease, peripheral vascular disease, and smoking." | 4.78 | Efficacy of doxazosin in specific hypertensive patient groups. ( Taylor, SH, 1991) |
| "Doxazosin showed a good antihypertensive effect in CRF patients when used as third drug in resistant severe hypertension." | 3.73 | [Doxazosine associated to renin-angiotensin blockers and calcioantagonists in chronic renal failure patients]. ( Calls, I; Gómez Campderá, F; Herrera, J; Liébana, A; Manjón, M; Marco, I; Martínez Fernández, I; Méndez, ML; Morey, A; Ocón, I; Pastors, L; Rincón, B; Robles, NR; Rodríguez Martínez, MA; Rodríguez Villareal, I; Tornero, F; Torrijos, I; Villatoro, J, 2005) |
| "Insulin resistance (IR) in chronic renal failure (CRF) is well-known." | 2.70 | Doxazosin, but not amlodipine decreases insulin resistance in patients with chronic renal failure: a prospective, randomized-controlled study. ( Akkaya, V; Celik, AV; Gürol, AO; Hursit, M; Karsidag, K; Kayacan, SM; Yazici, H; Yildiz, A, 2002) |
| "To assess the renal benefits of combined angiotensin-converting enzyme inhibition and alpha(1)-adrenergic antagonism, we studied the antihypertensive and renoprotective effects of temocapril (TMP) alone and in combination with doxazosin (DOX) in spontaneously hypertensive rats (SHR)/Izumo rats with renal ablation." | 1.32 | Renoprotective effect of angiotensin-converting enzyme inhibitor combined with alpha1-adrenergic antagonist in spontaneously hypertensive rats with renal ablation. ( Abe, K; Ito, O; Kanazawa, M; Kohzuki, M; Kurosawa, H; Minami, N; Saito, T; Yasujima, M, 2004) |
| "In this study, 15 patients with chronic renal failure were treated only with doxazosin and diuretics for 6 months and their blood pressure, renal parameters and lipid profile were measured." | 1.31 | Safety and availability of doxazosin in treating hypertensive patients with chronic renal failure. ( Amano, K; Fujiyama, S; Hasegawa, T; Iba, O; Iwasaka, T; Kosaki, A; Masaki, H; Matsubara, H; Mori, Y; Nose, A; Okigaki, M; Shibasaki, Y; Tanaka-Uchiyama, Y; Tateishi, E, 2001) |
| " After one dosage with a directly acting venodilator (nitroglycerin 5 mg s." | 1.28 | Compliance and reactivity of the peripheral venous system in chronic intermittent hemodialysis. ( Draaijer, P; Gladziwa, U; Kooman, JP; Leunissen, KM; Peltenburg, HG; Struyker-Boudier, HA; van Bortel, LM; van Hooff, JP; Wijnen, JA, 1992) |
| "Doxazosin was not appreciably dialyzable." | 1.27 | Pharmacokinetics and effect on blood pressure of doxazosin in normal subjects and patients with renal failure. ( Bailey, RR; Begg, EJ; Carlson, RV; Cowlishaw, MG; Sharman, JR, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakaigawa, N | 1 |
| Komatsu, R | 1 |
| Kamata, K | 1 |
| Ozaki, M | 1 |
| Yildiz, A | 1 |
| Hursit, M | 1 |
| Celik, AV | 1 |
| Kayacan, SM | 1 |
| Yazici, H | 1 |
| Akkaya, V | 1 |
| Gürol, AO | 1 |
| Karsidag, K | 1 |
| Kanazawa, M | 1 |
| Kohzuki, M | 1 |
| Kurosawa, H | 1 |
| Minami, N | 1 |
| Ito, O | 1 |
| Saito, T | 1 |
| Yasujima, M | 1 |
| Abe, K | 1 |
| Robles, NR | 1 |
| Gómez Campderá, F | 1 |
| Ocón, I | 1 |
| Manjón, M | 1 |
| Pastors, L | 1 |
| Herrera, J | 1 |
| Villatoro, J | 1 |
| Calls, I | 1 |
| Torrijos, I | 1 |
| Rodríguez Villareal, I | 1 |
| Rodríguez Martínez, MA | 1 |
| Méndez, ML | 1 |
| Morey, A | 1 |
| Martínez Fernández, I | 1 |
| Marco, I | 1 |
| Liébana, A | 1 |
| Rincón, B | 1 |
| Tornero, F | 1 |
| Dhaun, N | 1 |
| Ferro, CJ | 1 |
| Davenport, AP | 1 |
| Haynes, WG | 1 |
| Goddard, J | 1 |
| Webb, DJ | 1 |
| Kooman, JP | 2 |
| van Hooff, JP | 2 |
| Leunissen, KM | 2 |
| Martínez-Castelao, A | 1 |
| Hueso, M | 1 |
| Sanz, V | 1 |
| Rejas, J | 1 |
| Alsina, J | 1 |
| Grinyó, JM | 1 |
| Schwenger, V | 1 |
| Zeier, M | 1 |
| Ritz, E | 1 |
| Mori, Y | 1 |
| Matsubara, H | 1 |
| Nose, A | 1 |
| Shibasaki, Y | 1 |
| Masaki, H | 1 |
| Kosaki, A | 1 |
| Okigaki, M | 1 |
| Fujiyama, S | 1 |
| Tanaka-Uchiyama, Y | 1 |
| Hasegawa, T | 1 |
| Iba, O | 1 |
| Tateishi, E | 1 |
| Amano, K | 1 |
| Iwasaka, T | 1 |
| Wijnen, JA | 1 |
| Draaijer, P | 1 |
| van Bortel, LM | 1 |
| Gladziwa, U | 1 |
| Peltenburg, HG | 1 |
| Struyker-Boudier, HA | 1 |
| Taylor, SH | 1 |
| Carlson, RV | 1 |
| Bailey, RR | 1 |
| Begg, EJ | 1 |
| Cowlishaw, MG | 1 |
| Sharman, JR | 1 |
2 reviews available for doxazosin and Chronic Kidney Failure
| Article | Year |
|---|---|
The venous system and dialysis-associated hypotension.
Topics: Blood Volume; Body Fluid Compartments; Doxazosin; Humans; Hypertension, Renal; Hypotension; Kidney F | 1994 |
Efficacy of doxazosin in specific hypertensive patient groups.
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Cardiomegaly; Diabetes Mellitus, Type 2; Doxazosin | 1991 |
3 trials available for doxazosin and Chronic Kidney Failure
| Article | Year |
|---|---|
Doxazosin, but not amlodipine decreases insulin resistance in patients with chronic renal failure: a prospective, randomized-controlled study.
Topics: Adult; Amlodipine; Antihypertensive Agents; Doxazosin; Female; Homeostasis; Humans; Insulin Resistan | 2002 |
Haemodynamic and renal effects of endothelin receptor antagonism in patients with chronic kidney disease.
Topics: Adult; Blood Pressure; Cross-Over Studies; Double-Blind Method; Doxazosin; Enalapril; Endothelin Rec | 2007 |
Treatment of hypertension after renal transplantation: long-term efficacy of verapamil, enalapril, and doxazosin.
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Doxazosin; Enalapril; Female; Follow-Up St | 1998 |
7 other studies available for doxazosin and Chronic Kidney Failure
| Article | Year |
|---|---|
[Anesthetic management of a patient with pheochromocytoma and end-stage renal disease].
Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Anesthesia, General; Cervical Vertebrae; Chro | 2010 |
Renoprotective effect of angiotensin-converting enzyme inhibitor combined with alpha1-adrenergic antagonist in spontaneously hypertensive rats with renal ablation.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Albuminuria; Angiotensin-Conv | 2004 |
[Doxazosine associated to renin-angiotensin blockers and calcioantagonists in chronic renal failure patients].
Topics: Antihypertensive Agents; Calcium Channel Blockers; Doxazosin; Female; Humans; Hypertension; Kidney F | 2005 |
Antihypertensive therapy in renal patients - benefits and difficulties.
Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive A | 1999 |
Safety and availability of doxazosin in treating hypertensive patients with chronic renal failure.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Biological Availability; Blood P | 2001 |
Compliance and reactivity of the peripheral venous system in chronic intermittent hemodialysis.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Blood Pressure; Compliance; Doxazosin; Female; Humans; Hy | 1992 |
Pharmacokinetics and effect on blood pressure of doxazosin in normal subjects and patients with renal failure.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Doxazosin; F | 1986 |