doxazosin has been researched along with Cardiac Output, Low in 4 studies
Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
Cardiac Output, Low: A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In high-risk patients with hypertension, the higher risk for heart failure while taking doxazosin compared with chlorthalidone is attenuated but not eliminated by adding other antihypertensive drugs." | 5.10 | Relationship of antihypertensive treatment regimens and change in blood pressure to risk for heart failure in hypertensive patients randomly assigned to doxazosin or chlorthalidone: further analyses from the Antihypertensive and Lipid-Lowering treatment t ( Cutler, JA; Davis, BR; Farber, MA; Felicetta, JV; Furberg, CD; Stokes, JD; Wright, JT, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, BR | 1 |
| Cutler, JA | 1 |
| Furberg, CD | 1 |
| Wright, JT | 1 |
| Farber, MA | 1 |
| Felicetta, JV | 1 |
| Stokes, JD | 1 |
| Witte, KK | 1 |
| Thackray, SD | 1 |
| Nikitin, NP | 1 |
| Cleland, JG | 1 |
| Clark, AL | 1 |
| Verma, SP | 1 |
| Silke, B | 1 |
| Reynolds, GW | 1 |
| Kelly, JG | 1 |
| Richmond, A | 1 |
| Taylor, SH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000542] | Phase 3 | 0 participants | Interventional | 1993-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for doxazosin and Cardiac Output, Low
| Article | Year |
|---|---|
Relationship of antihypertensive treatment regimens and change in blood pressure to risk for heart failure in hypertensive patients randomly assigned to doxazosin or chlorthalidone: further analyses from the Antihypertensive and Lipid-Lowering treatment t
Topics: Antihypertensive Agents; Blood Pressure; Cardiac Output, Low; Chlorthalidone; Double-Blind Method; D | 2002 |
The effects of alpha and beta blockade on ventilatory responses to exercise in chronic heart failure.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Blood Pressure; Cardiac Output, Low; Chro | 2003 |
2 other studies available for doxazosin and Cardiac Output, Low
| Article | Year |
|---|---|
Summaries for patients. Blood pressure drugs and heart failure.
Topics: Antihypertensive Agents; Blood Pressure; Cardiac Output, Low; Chlorthalidone; Double-Blind Method; D | 2002 |
Vasodilator therapy for acute heart failure: haemodynamic comparison of hydralazine/isosorbide, alpha-adrenoceptor blockade, and angiotensin-converting enzyme inhibition.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Cardiac Output, | 1992 |