doxazosin has been researched along with Brain Neoplasms in 2 studies
Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This includes less toxic drugs, more selective towards tumor cells, causing less damage to the patient." | 5.43 | Phosphatidylinositol 3-Kinase/AKT Pathway Inhibition by Doxazosin Promotes Glioblastoma Cells Death, Upregulation of p53 and Triggers Low Neurotoxicity. ( Battastini, AM; Coelho, BP; de Quadros, AH; Gaelzer, MM; Gonçalves, CA; Guerra, MC; Guma, FC; Hoppe, JB; Salbego, CG; Setton-Avruj, P; Terra, SR; Usach, V, 2016) |
| " This includes less toxic drugs, more selective towards tumor cells, causing less damage to the patient." | 1.43 | Phosphatidylinositol 3-Kinase/AKT Pathway Inhibition by Doxazosin Promotes Glioblastoma Cells Death, Upregulation of p53 and Triggers Low Neurotoxicity. ( Battastini, AM; Coelho, BP; de Quadros, AH; Gaelzer, MM; Gonçalves, CA; Guerra, MC; Guma, FC; Hoppe, JB; Salbego, CG; Setton-Avruj, P; Terra, SR; Usach, V, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Staudacher, I | 1 |
| Jehle, J | 1 |
| Staudacher, K | 1 |
| Pledl, HW | 1 |
| Lemke, D | 1 |
| Schweizer, PA | 1 |
| Becker, R | 1 |
| Katus, HA | 1 |
| Thomas, D | 1 |
| Gaelzer, MM | 1 |
| Coelho, BP | 1 |
| de Quadros, AH | 1 |
| Hoppe, JB | 1 |
| Terra, SR | 1 |
| Guerra, MC | 1 |
| Usach, V | 1 |
| Guma, FC | 1 |
| Gonçalves, CA | 1 |
| Setton-Avruj, P | 1 |
| Battastini, AM | 1 |
| Salbego, CG | 1 |
2 other studies available for doxazosin and Brain Neoplasms
| Article | Year |
|---|---|
HERG K+ channel-dependent apoptosis and cell cycle arrest in human glioblastoma cells.
Topics: Apoptosis; Brain Neoplasms; Caspase 9; Cell Cycle Checkpoints; Cell Line, Tumor; Cytoprotection; Des | 2014 |
Phosphatidylinositol 3-Kinase/AKT Pathway Inhibition by Doxazosin Promotes Glioblastoma Cells Death, Upregulation of p53 and Triggers Low Neurotoxicity.
Topics: Animals; Antineoplastic Agents; Apoptosis; Astrocytes; Brain Neoplasms; Caspase 3; Cell Line, Tumor; | 2016 |