Page last updated: 2024-10-26

doxazosin and Brain Neoplasms

doxazosin has been researched along with Brain Neoplasms in 2 studies

Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
" This includes less toxic drugs, more selective towards tumor cells, causing less damage to the patient."5.43Phosphatidylinositol 3-Kinase/AKT Pathway Inhibition by Doxazosin Promotes Glioblastoma Cells Death, Upregulation of p53 and Triggers Low Neurotoxicity. ( Battastini, AM; Coelho, BP; de Quadros, AH; Gaelzer, MM; Gonçalves, CA; Guerra, MC; Guma, FC; Hoppe, JB; Salbego, CG; Setton-Avruj, P; Terra, SR; Usach, V, 2016)
" This includes less toxic drugs, more selective towards tumor cells, causing less damage to the patient."1.43Phosphatidylinositol 3-Kinase/AKT Pathway Inhibition by Doxazosin Promotes Glioblastoma Cells Death, Upregulation of p53 and Triggers Low Neurotoxicity. ( Battastini, AM; Coelho, BP; de Quadros, AH; Gaelzer, MM; Gonçalves, CA; Guerra, MC; Guma, FC; Hoppe, JB; Salbego, CG; Setton-Avruj, P; Terra, SR; Usach, V, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Staudacher, I1
Jehle, J1
Staudacher, K1
Pledl, HW1
Lemke, D1
Schweizer, PA1
Becker, R1
Katus, HA1
Thomas, D1
Gaelzer, MM1
Coelho, BP1
de Quadros, AH1
Hoppe, JB1
Terra, SR1
Guerra, MC1
Usach, V1
Guma, FC1
Gonçalves, CA1
Setton-Avruj, P1
Battastini, AM1
Salbego, CG1

Other Studies

2 other studies available for doxazosin and Brain Neoplasms

ArticleYear
HERG K+ channel-dependent apoptosis and cell cycle arrest in human glioblastoma cells.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Caspase 9; Cell Cycle Checkpoints; Cell Line, Tumor; Cytoprotection; Des

2014
Phosphatidylinositol 3-Kinase/AKT Pathway Inhibition by Doxazosin Promotes Glioblastoma Cells Death, Upregulation of p53 and Triggers Low Neurotoxicity.
    PloS one, 2016, Volume: 11, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Astrocytes; Brain Neoplasms; Caspase 3; Cell Line, Tumor;

2016